Abstract: Systems and methods are provided for automatically grouping branch devices based on device information (e.g., IPSec tunnel connectivity, etc.). The devices with similar branch gateways which would customarily receive similar route information and/or properties (e.g., AS-PATH, cost, MED, Metric1, Metric2, community/extended community) and/or devices with similar connectivity graphs can be grouped together. This can reduce the number of electronic communications transmitted throughout the network and increase computational efficiency for the controller and devices.

Abstract: Systems and methods are provided for automatically grouping branch devices based on device information (e.g., IPSec tunnel connectivity, etc.). The devices with similar branch gateways which would customarily receive similar route information and/or properties (e.g., AS-PATH, cost, MED, Metric1, Metric2, community/extended community) and/or devices with similar connectivity graphs can be grouped together. This can reduce the number of electronic communications transmitted throughout the network and increase computational efficiency for the controller and devices.

Abstract: Systems and methods are provided for automatically grouping branch devices based on device information (e.g., IPSec tunnel connectivity, etc.). The devices with similar branch gateways which would customarily receive similar route information and/or properties (e.g., AS-PATH, cost, MED, Metric1, Metric2, community/extended community) and/or devices with similar connectivity graphs can be grouped together. This can reduce the number of electronic communications transmitted throughout the network and increase computational efficiency for the controller and devices.

Abstract: Systems and methods are provided for automatically grouping branch devices based on device information (e.g., IPSec tunnel connectivity, etc.). The devices with similar branch gateways which would customarily receive similar route information and/or properties (e.g., AS-PATH, cost, MED, Metric1, Metric2, community/extended community) and/or devices with similar connectivity graphs can be grouped together. This can reduce the number of electronic communications transmitted throughout the network and increase computational efficiency for the controller and devices.

Abstract: An example network infrastructure device of a software defined wide area network (SD-WAN) comprises processing circuitry and a memory including instructions that cause the network infrastructure device to advertise a set of SD-WAN overlay tunnels terminating at the network infrastructure device, receive a network connectivity graph including a categorized set of network infrastructure devices that are members of an advertisement area and links between the set of network infrastructure devices, receive data traffic intended for a destination device of the set of network infrastructure devices, determine, based on the network connectivity graph, a preferred path to the destination device, and transmit the data traffic via an interface associated with the preferred path.

Abstract: Systems and methods of software-defined wide area network (SDWAN) device routing are provided using a cloud-based overlay routing service that utilizes, a cloud-BGP service (CBS), and a path computation module (PCM), and overlay agents (OAs) implemented on the tenant side. The Oas, CBS, and PCM may interact with each other, e.g., publish/update local states, route prefixes, etc. to create/maintain routing in the SDWAN.

Abstract: Systems and methods of software-defined wide area network (SDWAN) device routing are provided using a cloud-based overlay routing service that utilizes, a cloud-BGP service (CBS), and a path computation module (PCM), and overlay agents (OAs) implemented on the tenant side. The Oas, CBS, and PCM may interact with each other, e.g., publish/update local states, route prefixes, etc. to create/maintain routing in the SDWAN.

Abstract: In some examples, a computing device comprises a virtual network endpoint; a network interface card (NIC) comprising a first hardware component and a second hardware component, wherein the first hardware component and the second hardware component provide separate packet input/output access to a physical network interface of the NIC, wherein the NIC is configured to receive a packet inbound from the physical network interface; and a virtual router to receive the packet from the NIC and output, using the first hardware component, in response to determining a destination endpoint of the packet is the virtual network endpoint, the packet back to the NIC, wherein the NIC is further configured to switch, in response to receiving the packet from the virtual router, the packet to the virtual network endpoint and to output, using the second hardware component, the packet to the virtual network endpoint.

Abstract: In some examples, a computing device comprises a virtual network endpoint; a network interface card (NIC) comprising a first hardware component and a second hardware component, wherein the first hardware component and the second hardware component provide separate packet input/output access to a physical network interface of the NIC, wherein the NIC is configured to receive a packet inbound from the physical network interface; and a virtual router to receive the packet from the NIC and output, using the first hardware component, in response to determining a destination endpoint of the packet is the virtual network endpoint, the packet back to the NIC, wherein the NIC is further configured to switch, in response to receiving the packet from the virtual router, the packet to the virtual network endpoint and to output, using the second hardware component, the packet to the virtual network endpoint.

Abstract: In some examples, a computing device comprises a virtual network endpoint; a network interface card (NIC) comprising a first hardware component and a second hardware component, wherein the first hardware component and the second hardware component provide separate packet input/output access to a physical network interface of the NIC, wherein the NIC is configured to receive a packet inbound from the physical network interface; and a virtual router to receive the packet from the NIC and output, using the first hardware component, in response to determining a destination endpoint of the packet is the virtual network endpoint, the packet back to the NIC, wherein the NIC is further configured to switch, in response to receiving the packet from the virtual router, the packet to the virtual network endpoint and to output, using the second hardware component, the packet to the virtual network endpoint.

Abstract: In some examples, a computing device comprises a virtual network endpoint; a network interface card (NIC) comprising a first hardware component and a second hardware component, wherein the first hardware component and the second hardware component provide separate packet input/output access to a physical network interface of the NIC, wherein the NIC is configured to receive a packet inbound from the physical network interface; and a virtual router to receive the packet from the NIC and output, using the first hardware component, in response to determining a destination endpoint of the packet is the virtual network endpoint, the packet back to the NIC, wherein the NIC is further configured to switch, in response to receiving the packet from the virtual router, the packet to the virtual network endpoint and to output, using the second hardware component, the packet to the virtual network endpoint.

Abstract: Provided herein are tandem Fcs and tandem Fc antibodies (“TFcAs”), e.g., tandem Fc bispecific antibodies (“TFcBAs”), which comprise one or at least two binding sites that specifically bind to one or more cell surface receptors. The binding sites are connected through a TFc, which TFc comprises a first Fc region and a second Fc region, wherein the first and the second Fc regions are linked through a TFc linker to form a contiguous polypeptide and dimerize to form an Fc dimer. Exemplary TFcBAs inhibit signal transduction through the cell surface receptor(s) for which the binding sites of the TFcBA are specific.

Abstract: Provided herein are tandem Fcs and tandem Fc antibodies (“TFcAs”), e.g., tandem Fc bispecific antibodies (“TFcBAs”), which comprise one or at least two binding sites that specifically bind to one or more cell surface receptors. The binding sites are connected through a TFc, which TFc comprises a first Fc region and a second Fc region, wherein the first and the second Fc regions are linked through a TFc linker to form a contiguous polypeptide and dimerize to form an Fc dimer. Exemplary TFcBAs bind to the cell surface receptors c-Met and EpCam and inhibit signal transduction through the cell surface receptor(s) for which the binding sites of the TFcBA are specific.

Abstract: Provided herein are tandem Fcs and tandem Fc antibodies (“TFcAs”), e.g., tandem Fc bispecific antibodies (“TFcBAs”), which comprise one or at least two binding sites that specifically bind to one or more cell surface receptors. The binding sites are connected through a TFc, which TFc comprises a first Fc region and a second Fc region, wherein the first and the second Fc regions are linked through a TFc linker to form a contiguous polypeptide and dimerize to form an Fc dimer. Exemplary TFcBAs bind to the cell surface receptors c-Met and EpCam and inhibit signal transduction through the cell surface receptor(s) for which the binding sites of the TFcBA are specific.

Abstract: Provided herein are tandem Fcs and tandem Fc antibodies (“TFcAs”), e.g., tandem Fc bispecific antibodies (“TFcBAs”), which comprise one or at least two binding sites that specifically bind to one or more cell surface receptors. The binding sites are connected through a TFc, which TFc comprises a first Fc region and a second Fc region, wherein the first and the second Fc regions are linked through a TFc linker to form a contiguous polypeptide and dimerize to form an Fc dimer. Exemplary TFcBAs bind to the cell surface receptors c-Met and EpCam and inhibit signal transduction through the cell surface receptor(s) for which the binding sites of the TFcBA are specific.

Abstract: Provided herein are tandem Fcs and tandem Fc antibodies (“TFcAs”), e.g., tandem Fc bispecific antibodies (“TFcBAs”), which comprise one or at least two binding sites that specifically bind to one or more cell surface receptors. The binding sites are connected through a TFc, which TFc comprises a first Fc region and a second Fc region, wherein the first and the second Fc regions are linked through a TFc linker to form a contiguous polypeptide and dimerize to form an Fc dimer. Exemplary TFcBAs inhibit signal transduction through the cell surface receptor(s) for which the binding sites of the TFcBA are specific.

Abstract: Methods, systems, configurations, and computer program products create, represent, and manage Business Object Documents (BODs), coordinating the interfaces between two or more computer systems exchanging transactions thru a messaging architecture. The online validation of a BOD to prevent spoofing is performed by use of a relational database. While some aspects of the invention deal with the general e-business exchange of documents, others add versioning and verification to transactions via a repository that is used for that purpose. The repository is also used for the management of design of the electronic documents during the creations of the system between systems. Thru the use of a relational database business object document verification by relational repository (BODVRR) is able to perform automated validation of a versioned BOD in a business environment.

Abstract: A control circuit for switching AC or DC loads and for automatically discerning the presence of an AC or a DC power supply via a switch has been provided. The control circuit is coupled to alternately render a switch operative and non-operative wherein the switch is coupled across a load which is powered up by either an AC or a DC power supply. The control circuit includes an AC/DC discernment circuit for ascertaining whether the load is powered up by an AC or a DC power supply. The control circuit also includes circuitry for comparing signals sensed by the switch with predetermined thresholds (which are a function of whether an AC or DC determination has been made) for providing logic signals to control the operation of the switch.

Abstract: A low impedance load is switched between a power supply source and ground through a series connected power MOSFET the conduction of which is controlled by a switching circuit. The switching circuit includes a linear loop that regulates the switch voltage to a minimum value to produce current flow through the load and the MOSFET. In addition, the switching circuit includes a current supply placed in parallel to the MOSFET which is set to supply a minimum predetermined current that is representative of the value of current flow through the load under an open load condition. If the load current falls below this set current value an open load status flag is provided by the switching circuit as the loop is no longer in regulation.