Patents by Inventor Stephen Swisher

Stephen Swisher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods involving MDA-7 for the treatment of cancer
    Publication number: 20070009484
    Abstract: The present invention concerns methods and compositions involving MDA-7 protein or an MDA-7-encoding nucleic acid in combination with either 1) a COX-2 selective inhibitor, such as celecoxib, 2) an Hsp90 inhibitor, such as geldanamycin, or a geldanamycin derivative or analog, 3) a vitamin E compound, for the treatment of cancer, 4) a TNF, such as TNF-alpha, 5) a VEGF inhibitor, or 6) an inhibitor of IL-10. In certain examples, a treatment for breast cancer is provided. In other examples a treatment for lung cancer is provided. Such examples involve, in some cases, an adenovirus vector that expresses MDA-7 protein.
    Type: Application
    Filed: February 8, 2006
    Publication date: January 11, 2007
    Inventors: Kelly Hunt, Young-Jin Suh, Stephen Swisher, Abujiang Pataer, Rajagopal Ramesh, Manish Shanker
  • Induction of apoptic or cytotoxic gene expression by adenoviral mediated gene codelivery
    Publication number: 20060002895
    Abstract: The present invention generally relates to viral vectors and their use as expression vectors for transforming human cells, both in vitro and in vivo. More particularly, the present invention relates to adenoviral vectors containing propapoptotic genes and their use in cancer therapy.
    Type: Application
    Filed: May 31, 2005
    Publication date: January 5, 2006
    Inventors: Timothy McDonnell, Stephen Swisher, Bingliang Fang, Elizabeth Bruckheimer, Mona Sarkiss, Lin Ji, Jack Roth