Patents by Inventor Stephen Taro JOY

Stephen Taro JOY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALPHA3BETA HYDROGEN BOND SURROGATE MACROCYCLES AS MODULATORS OF RAS
    Publication number: 20170066801
    Abstract: The present invention relates to peptides having a stable, internally-constrained HBS ?-helix, where the peptide mimics at least a portion of the ?-H helix of the Sos protein and contains a mixture of alpha and beta amino acid residues in the pattern ?3/?1. Methods using the peptides of the present invention for inhibiting Ras signaling in a cell, promoting cell death, and treating, preventing, and/or diagnosing a cellular proliferative disorder, differentiative disorder, and/or neoplastic condition in a subject in need thereof are also disclosed.
    Type: Application
    Filed: February 23, 2015
    Publication date: March 9, 2017
    Applicant: NEW YORK UNIVERSITY
    Inventors: Paramjit S. ARORA, Dafna BAR-SAGI, Stephen Taro JOY, Seth NICKERSON