Patents by Inventor Stephen Thibodeau

Stephen Thibodeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF DIFFERENTIALLY EXPRESSED NUCLEIC ACID SEQUENCES AS BIOMARKERS FOR CANCER
    Publication number: 20080233585
    Abstract: The present invention relates to novel marker sequences that are differentially expressed in cancer cells or tissue of a subject with cancerous conditions. The present invention also relates to assays for diagnosis, prognosis, staging, monitoring, therapeutic treatment, and marker sequence related agents including probes, primers, antibodies, and therapeutic compositions.
    Type: Application
    Filed: March 13, 2008
    Publication date: September 25, 2008
    Inventors: Christopher Burgess, Susan Myerow, Arunthathi Thiagalingam, Peter Maimonis, Gary Molino, Lawrence Burgart, Lisa Allyn Boardman, Stephen Thibodeau, Marcia Lewis
  • Method for detecting a differentially expressed sequence
    Patent number: 7258973
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 21, 2007
    Assignees: Mayo Foundation for Medical Education & Research, Bayer Healthcare, LLC
    Inventors: Jon H. Astle, Christopher C. Burgess, Theodore J. Catino, Poornima Dwivedi, Marcia E. Lewis, Gary A. Molino, Susan H. Myerow, Arunthathi Thiagalingam, Stephen Thibodeau, Lawrence J. Burgart, Lisa Allyn Boardman
  • Alterations in the Copy Number of the SULT1A1 Gene
    Publication number: 20070178493
    Abstract: Methods are described for determining sulfonator status of a patient and determining dosages of drugs based on copy number of the SULT1A1 gene.
    Type: Application
    Filed: November 14, 2006
    Publication date: August 2, 2007
    Inventors: Richard Weinshilboum, Araba Adjei, Scott Hebbring, Stephen Thibodeau
  • Alterations in the copy number of the SULT1A1 gene
    Publication number: 20070134675
    Abstract: Methods are described for determining sulfonator status of a patient and determining dosages of drugs based on copy number of the SULT1A1 gene.
    Type: Application
    Filed: December 8, 2005
    Publication date: June 14, 2007
    Inventors: Scott Hebbring, Stephen Thibodeau, Araba Adjei, Richard Weinshilboum
  • Human genes and gene expression products: II
    Patent number: 7211398
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 1, 2007
    Assignees: Bayer Corporation, Mayo Foundation for Medical Education and Research
    Inventors: Jon H. Astle, Christopher C. Burgess, Theodore J. Catino, Poornima Dwivedi, Marcia E. Lewis, Gary A. Molino, Susan H. Myerow, Arunthathi Thiagalingam, Stephen Thibodeau, Lawrence J. Burgart, Lisa Allyn Boardman
  • Use of differentially expressed nucleic acid sequences as biomarkers for cancer
    Publication number: 20060188889
    Abstract: The present invention relates to novel marker sequences that are differentially expressed in cancer cells or tissue of a subject with cancerous conditions. The present invention also relates to assays for diagnosis, prognosis, staging, monitoring, therapeutic treatment, and marker sequence related agents including probes, primers, antibodies, and therapeutic compositions.
    Type: Application
    Filed: November 4, 2003
    Publication date: August 24, 2006
    Inventors: Christopher Burgess, Susan Myerow, Arunthathi Thiagalingam, Peter Maimonis, Gary Molino, Lawrence Burgart, Lisa Boardman, Stephen Thibodeau, Marcia Lewis
  • Nucleic acid sequences differentially expressed in cancer tissue
    Publication number: 20060179496
    Abstract: This invention relates to novel nucleic acid sequences which are differentially expressed in cancer cells. The invention also relates to proteins and peptides encoded by the sequences, to diagnostic assays and therapeutic agents based on the sequences and proteins, and to probes, antisense constructs, and antibodies derived from the sequences and proteins or peptides. The subject nucleic acids have been found to be differentially expressed by tumor cells, particularly in colon cancer tissue.
    Type: Application
    Filed: July 26, 2005
    Publication date: August 10, 2006
    Inventors: Christopher Burgess, Jon Astle, Eddie Carroll, Theodore Catino, Poornima Dwivedi, Gary Molino, Arunthathi Thiagalingam, Marcia Lewis, Stephen Thibodeau, Lawrence Burgart, Lisa Boardman
  • Differential expression of genes in microsatellite instability
    Publication number: 20060134653
    Abstract: The present invention relates to nucleic acid sequences which are overexpressed in colorectal tumors which display a high level of microsatellite instability (MSI-H) vs. tumors displaying a low level of microsatellite instability (MSS), and can thus be used to identify MSI-H in a patient, and be used further to facilitate patient prognosis, monitor disease progression/regression, identify appropriate treatment regimes, and evaluate the efficacy of treatment.
    Type: Application
    Filed: April 13, 2005
    Publication date: June 22, 2006
    Inventors: Christopher Burgess, Theodore Catino, Gary Molino, Susan Myerow, Arunthathi Thiagalingam, Marcia Lewis, Stephen Thibodeau, Lisa Boardman, Lawrence Burgart
  • Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer
    Publication number: 20050266493
    Abstract: The invention relates to newly discovered nucleic acid molecules and proteins associated with colon cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human colon cancers are provided.
    Type: Application
    Filed: July 21, 2005
    Publication date: December 1, 2005
    Inventors: Allison Berger, Tracy Guillemette, Robert Schlegel, John Monahan, Shubhangi Kamatkar, Stephen Thibodeau, Lawrence Burgart