Patents by Inventor Stephen Wald

Stephen Wald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal salts and uses thereof
    Patent number: 12258303
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: December 7, 2023
    Date of Patent: March 25, 2025
    Assignee: Inspirna, Inc.
    Inventors: Stephen Wald, Eduardo J. Martinez, Samuel Stratford, Amanda Buist, Joseph Benson, Jonathan Loughrey
  • METAL SALTS AND USES THEREOF
    Publication number: 20240174595
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Application
    Filed: December 7, 2023
    Publication date: May 30, 2024
    Inventors: Stephen WALD, Eduardo J. MARTINEZ, Samuel STRATFORD, Amanda BUIST, Joseph BENSON, Jonathan LOUGHREY
  • Metal salts and uses thereof
    Patent number: 11878956
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: January 23, 2024
    Assignee: Inspirna, Inc.
    Inventors: Stephen Wald, Eduardo J. Martinez, Samuel Stratford, Amanda Buist, Joseph Benson, Jonathan Loughrey
  • METAL SALTS AND USES THEREOF
    Publication number: 20230095288
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Application
    Filed: August 23, 2022
    Publication date: March 30, 2023
    Inventors: Stephen WALD, Eduardo J. MARTINEZ, Samuel STRATFORD, Amanda BUIST, Joseph BENSON, Jonathan LOUGHREY
  • Metal salts and uses thereof
    Patent number: 11459292
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: October 4, 2022
    Assignee: Inspirna, Inc.
    Inventors: Stephen Wald, Eduardo J. Martinez, Samuel Stratford, Amanda Buist, Joseph Benson, Jonathan Loughrey
  • METAL SALTS AND USES THEREOF
    Publication number: 20220041541
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Application
    Filed: August 20, 2021
    Publication date: February 10, 2022
    Inventors: Stephen WALD, Eduardo J. MARTINEZ, Samuel STRATFORD, Amanda BUIST, Joseph BENSON, Jonathan LOUGHREY
  • Polymorphs and uses thereof
    Patent number: 11214536
    Abstract: The present invention relates to new polymorphs of LXR? agonists which exhibit improved physical properties. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of an LXR? agonist, as well as methods of treating cancer including administration of a formulation including an LXR? agonist to a subject in need thereof.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: January 4, 2022
    Assignee: Inspirna, Inc.
    Inventors: Saurabh Chitre, Hayley Reece, Stephen Wald
  • Metal salts and uses thereof
    Patent number: 11174220
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: November 16, 2021
    Assignee: Inspirna, Inc.
    Inventors: Stephen Wald, Eduardo J. Martinez, Samuel Stratford, Amanda Buist, Joseph Benson, Jonathan Loughrey
  • METAL SALTS AND USES THEREOF
    Publication number: 20210179539
    Abstract: The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 17, 2021
    Inventors: Stephen WALD, Eduardo J. MARTINEZ, Samuel STRATFORD, Amanda BUIST, Joseph BENSON, Jonathan LOUGHREY
  • POLYMORPHS AND USES THEREOF
    Publication number: 20200317605
    Abstract: The present invention relates to new polymorphs of LXRP agonists which exhibit improved physical properties. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of an LXRP agonist, as well as methods of treating cancer including administration of a formulation including an LXRP agonist to a subject in need thereof.
    Type: Application
    Filed: November 20, 2018
    Publication date: October 8, 2020
    Inventors: Saurabh CHITRE, Hayley REECE, Stephen WALD
  • AUTOMATED COMPUTING SYSTEM PERSONALIZATION
    Publication number: 20160094391
    Abstract: The personalization of the functionality of a computing system. In response to identifying the user to personalize its functionality to, the computing system self-personalizes by automatically requesting personalization information for the identified user from a remote personalization engine. The resulting received personalized information is then applied to the computing system to at least partially personalize the functionality of the computing system to the identified user.
    Type: Application
    Filed: September 30, 2014
    Publication date: March 31, 2016
    Inventors: Bahram Bahram Pour, Stephen Wald
  • Lactose-free, non-hygroscopic and anhydrous pharmaceutical compositions of descarboethoxyloratadine
    Publication number: 20060079489
    Abstract: Stable pharmaceutical compositions of descarboethoxyloratadine (DCL), a metabolic derivative of loratadine, for the treatment of allergic rhinitis and other histamine-induced disorders are disclosed. The compositions are formulated to avoid the incompatibility between DCL and reactive excipients such as lactose and other mono- and di-saccharides. Disclosed compositions include lactose-free, non-hygroscopic and anhydrous stable pharmaceutical compositions of DCL.
    Type: Application
    Filed: December 2, 2005
    Publication date: April 13, 2006
    Applicant: Sepracor Inc.
    Inventors: Martin Redmon, Hal Butler, Stephen Wald, Paul Rubin