Patents by Inventor Stephen Wank

Stephen Wank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of pentagastrin to inhibit gastric acid secretion or as a diuretic
    Patent number: 8853356
    Abstract: This invention pertains to the discovery that pentagastrin, when administered in conjunction with a proton pump inhibitor (PPI) is synergistic with the PPI and significantly increases the efficacy of the PPI in reducing/mitigating excess gastric acid secretion.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: October 7, 2014
    Assignee: The Regents of the University of California
    Inventors: Joseph R. Pisegna, Stephen Wank
  • Use of pentagastrin to inhibit gastric acid secretion or as a diuretic
    Patent number: 7807623
    Abstract: This invention pertains to the discovery administration of a CCK receptor agonist can increase urinary sodium excretion and/or free water excretion in a mammal. CCK receptor agonist can thereby be used in the treatment of conditions such high blood pressure, fluid retention associated with heart failure, fluid retention associated with acute or chronic kidney failure, fluid retention associated with cirrhosis, fluid retention associated with liver failure, calcium kidney stones, nephrogenic diabetes insipidus, and renal tubular acidosis.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: October 5, 2010
    Assignee: The Regents of the University of California
    Inventors: Joseph R. Pisegna, Stephen Wank
  • USE OF PENTAGASTRIN TO INHIBIT GASTRIC ACID SECRETION OR AS A DIURETIC
    Publication number: 20080045462
    Abstract: This invention pertains to the discovery that pentagastrin, when administered in conjunction with a proton pump inhibitor (PPI) is synergistic with the PPI and significantly increases the efficacy of the PPI in reducing/mitigating excess gastric acid secretion.
    Type: Application
    Filed: July 30, 2007
    Publication date: February 21, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Joseph Pisegna, Stephen Wank
  • USE OF PENTAGASTRIN TO INHIBIT GASTRIC ACID SECRETION OR AS A DIURETIC
    Publication number: 20070207959
    Abstract: This invention pertains to the discovery that pentagastrin, when administered in conjunction with a proton pump inhibitor (PPI) is synergistic with the PPI and significantly increases the efficacy of the PPI in reducing/mitigating excess gastric acid secretion.
    Type: Application
    Filed: December 8, 2006
    Publication date: September 6, 2007
    Inventors: JOSEPH PISEGNA, STEPHEN WANK
  • Cloning and characterization of calcitonin gene related peptide receptors
    Publication number: 20040110170
    Abstract: This invention provides CGRP receptors (including both amino acid and nucleic acid sequences). Compositions which include these polypeptides, proteins, nucleic acids, recombinant cells, transgenic animals, and antibodies to the receptors are also provided.
    Type: Application
    Filed: May 16, 2003
    Publication date: June 10, 2004
    Applicant: The Regents of the University of California
    Inventors: Joseph R. Pisegna, Stephen A. Wank
  • Cloning and functional expression of cholecystokinin/gastrin receptor-encoding DNA
    Patent number: 6169173
    Abstract: An unconventional approach to purifying CCK receptor protein to sequenceable-grade homogeneity has been discovered. By this approach, CCK receptor protein can be obtained and sequenced routinely from a variety sources, and from the sequence information thus obtained it is possible to prepare oligonucleotides suitable for cloning CCK receptor genes. “CCK receptor” in this context denotes, any from a group of proteins that displays a characteristic CCK binding affinity and that is encoded by a nucleotide sequence which hybridizes a oligonucleotide probe designed in accordance with the criteria elaborated herein.
    Type: Grant
    Filed: March 10, 1993
    Date of Patent: January 2, 2001
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Stephen A. Wank
  • Method of purifying cholecystokinin receptor protein
    Patent number: 5319073
    Abstract: An unconventional approach to purifying CCK receptor protein to sequenceable-grade homogeneity has been discovered. By this approach, CCK receptor protein can be obtained and sequenced routinely from a variety sources, and from the sequence information thus obtained it is possible to prepare oligonucleotides suitable for cloning CCK receptor genes. "CCK receptor" in this context denotes any from a group of proteins that displays a characteristic CCK binding affinity and that is encoded by a nucleotide sequence which hybridizes a oligonucleotide probe designed in accordance with the criteria elaborated herein.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: June 7, 1994
    Assignee: The United States of America, as represented by the Department of Health & Human Services
    Inventor: Stephen A. Wank