Abstract: Compositions and methods of use thereof for delivering an insecticide to water-borne insect larvae are provided. Whereas individual cells of the insecticidal bacteria such as Bacillus thuringiensis israelensis (Bti), are effective in killing insect larvae when ingested by same, their use in aqueous environments is restricted by the time that the bacterial cells remain suspended in water and hence available for ingestion by the larvae. To increase the time that the insecticidal bacteria remain in suspension, it has now been found advantageous to mix bacterial suspensions with nanoparticles comprising carbon that attach to the external surface of the cells.

Abstract: In some examples, a first electronic control unit (ECU) receives zone sensor data of a plurality of zones associated with a vehicle. For instance, a respective second ECU and a respective set of zone sensors is associated with each respective zone of the plurality of zones. Based on an indicated driving mode of the vehicle, the first ECU may perform recognition on the zone sensor data from a first zone of the plurality of zones to determine first recognition information. The first ECU receives second recognition information from the respective second ECUs of the respective zones. For instance, the respective second ECUs are configured to perform recognition processing on respective zone sensor data from the set of zone sensors of the respective zones. Based on the first recognition information and the second recognition information, the first ECU sends at least one control signal to at least one vehicle actuator.

Abstract: Systems and methods for provisioning system components to execute jobs are provided. In one embodiment, a method is provided that includes receiving a request to provision system components for executing a job. Aggregate latencies for computing units may be calculated based on startup latencies for jobs executing on the computing units. A particular computing unit may be selected from among the plurality of computing units based on the aggregate latencies, and system components may be provisioned from the computing unit.

Abstract: A method performed by a computing system includes detecting that a removable data volume has been attached to the computing system, the removable data volume being identified by a unique label. The method further includes, in response to determining that a portion of the unique label matches a predefined value, invoking a catalog container based on a rule within a first rule database. The method further includes, with the catalog container, obtaining metadata stored on the removable data volume, the metadata including characteristics of a first application associated with a first piece of data that is stored on the removable data volume. The method further includes, with the catalog container, creating an application container having the first application with the characteristics. The method further includes, with the application container, processing the removable data volume.

Abstract: This invention relates to cocrystals of naloxone and of naltrexone and their use as opioid antagonists. The cocrystals of the invention include naloxone isonicotinamide cocrystal, naloxone hydrochloride piperazine cocrystal, naltrexone menthol cocrystal, naltrexone thymine cocrystal, naltrexone 2,5-dihydroxybenzoic acid cocrystal, naltrexone salicylic acid cocrystal, naltrexone hydrochloride piperazine cocrystal and naltrexone hydrochloride sulfathiazole cocrystal. A drug-in¬ adhesive transdermal patch containing the opioid analgesic fentanyl or an analog thereof and a cocrystal of naloxone or naltrexone is disclosed. Also disclosed is a method of treating pain, such as acute, chronic or intermittent pain, by applying a drug-in-adhesive transdermal patch of the invention to the skin of a patient in need thereof.

Abstract: Systems and methods for provisioning system components to execute jobs are provided. In one embodiment, a method is provided that includes receiving a request to provision system components for executing a job. Aggregate latencies for computing units may be calculated based on startup latencies for jobs executing on the computing units. A particular computing unit may be selected from among the plurality of computing units based on the aggregate latencies, and system components may be provisioned from the computing unit.

Abstract: Systems and methods for provisioning system components to execute jobs are provided. In one embodiment, receiving a request to provision system components of computing units for executing a job. An aggregate latency may be calculated for each of the computing units based on a startup latency for each job executing on the computing units. A computing unit with a lowest aggregate latency may be identified, and system components may be provisioned from the computing unit with the lowest aggregate latency.

Abstract: This invention relates to crystalline salts of naloxone and of naltrexone and their use as opioid antagonists. The crystalline salts of the invention include naloxone saccharinate, naltrexone succinate and a methanol solvate of naltrexone succinate. A drug-in-adhesive transdermal patch containing the opioid analgesic fentanyl or an analog thereof and a crystalline salts of naloxone or naltrexone is disclosed. Also disclosed is a method of treating pain, such as acute, chronic or intermittent pain, by applying a drug-in-adhesive transdermal patch of the invention to the skin of a patient in need thereof.

Abstract: Systems and methods for provisioning system components to execute jobs are provided. In one embodiment, receiving a request to provision system components of computing units for executing a job. An aggregate latency may be calculated for each of the computing units based on a startup latency for each job executing on the computing units. A computing unit with a lowest aggregate latency may be identified, and system components may be provisioned from the computing unit with the lowest aggregate latency.

Abstract: A bracket for extensibly mounting a medical or surgical apparatus, and more particularly a humidification apparatus, to a support structure. The bracket comprises a base member securable to the support structure, a mounting member to which the humidification apparatus may be secured, and an extension mechanism moveably engaging the base member and the mounting member. The mounting member is reversibly extensible from a retracted position substantially proximate the base member to an extended position projecting beyond the base member. Also disclosed are a humidification apparatus and a support stand each comprising the extensible bracket.

Abstract: Compositions and methods of use thereof for delivering an insecticide to water-borne insect larvae are provided. Whereas individual cells of the insecticidal bacteria such as Bacillus thuringiensis israelensis (Bti), are effective in killing insect larvae when ingested by same, their use in aqueous environments is restricted by the time that the bacterial cells remain suspended in water and hence available for ingestion by the larvae. To increase the time that the insecticidal bacteria remain in suspension, it has now been found advantageous to mix bacterial suspensions with nanoparticles comprising carbon that attach to the external surface of the cells.

Abstract: This invention relates to crystalline salts of naloxone and of naltrexone and their use as opioid antagonists. The crystalline salts of the invention include naloxone saccharinate, naltrexone succinate and a methanol solvate of naltrexone succinate. A drug-in-adhesive transdermal patch containing the opioid analgesic fentanyl or an analog thereof and a crystalline salts of naloxone or naltrexone is disclosed. Also disclosed is a method of treating pain, such as acute, chronic or intermittent pain, by applying a drug-in-adhesive transdermal patch of the invention to the skin of a patient in need thereof.

Abstract: This invention relates to cocrystals of naloxone and of naltrexone and their use as opioid antagonists. The cocrystals of the invention include naloxone isonicotinamide cocrystal, naloxone hydrochloride piperazine cocrystal, naltrexone menthol cocrystal, naltrexone thymine cocrystal, naltrexone 2,5-dihydroxybenzoic acid cocrystal, naltrexone salicylic acid cocrystal, naltrexone hydrochloride piperazine cocrystal and naltrexone hydrochloride sulfathiazole cocrystal. A drug-in¬ adhesive transdermal patch containing the opioid analgesic fentanyl or an analog thereof and a cocrystal of naloxone or naltrexone is disclosed. Also disclosed is a method of treating pain, such as acute, chronic or intermittent pain, by applying a drug-in-adhesive transdermal patch of the invention to the skin of a patient in need thereof.

Abstract: A method performed by a computing system includes detecting that a removable data volume has been attached to the computing system, the removable data volume being identified by a unique label. The method further includes, in response to determining that a portion of the unique label matches a predefined value, invoking a catalog container based on a rule within a first rule database. The method further includes, with the catalog container, obtaining metadata stored on the removable data volume, the metadata including characteristics of a first application associated with a first piece of data that is stored on the removable data volume. The method further includes, with the catalog container, creating an application container having the first application with the characteristics. The method further includes, with the application container, processing the removable data volume.

Abstract: A bracket for extensibly mounting a medical or surgical apparatus, and more particularly a humidification apparatus, to a support structure. The bracket comprises a base member securable to the support structure, a mounting member to which the humidification apparatus may be secured, and an extension mechanism moveably engaging the base member and the mounting member. The mounting member is reversibly extensible from a retracted position substantially proximate the base member to an extended position projecting beyond the base member. Also disclosed are a humidification apparatus and a support stand each comprising the extensible bracket.

Abstract: A 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal and its use as an opioid antagonist are disclosed. The invention also relates to a drug-in-adhesive transdermal patch containing the analgesic fentanyl, a mu opioid agonist, or an analog thereof and a 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal, as an opioid antagonist. A transdermal patch of the invention is tamper-resistant and an abuse deterrent which protects against drug misuse or abuse. The invention also provides a method of treating pain, such as acute, chronic, or intermittent pain, by applying a drug-in-adhesive transdermal patch according to the invention to the skin of a patient in need thereof. Also disclosed is an improved transdermal patch for administering fentanyl or an analog thereof, or for administering a mu opioid agonist, the improvement wherein the transdermal patch contains a 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal in an abuse limiting amount.

Abstract: The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline genistein potassium salt dihydrate; crystalline genistein calcium salt; crystalline genistein magnesium salt; crystalline genistein L-lysine salt; crystalline genistein N-methylglucamine salt; crystalline genistein N-ethylglucamine salt; crystalline genistein diethylamine salt; and crystalline genistein monohydrate. The disclosure also relates to the novel genistein salts represented by these crystalline forms. Therapeutic compositions containing at least one of these crystalline forms of genistein and/or a genistein salt and a pharmaceutically acceptable carrier are described.

Abstract: A re-processing method for isolating a marketable free iron product and a non-metallic co-product from small-particulate metal production by-product is provided. The re-processing method may be adapted so that the resulting free iron product is marketable granules of various sizes and properties. The method may include refining the metal production by-product into a suitably sized and spaced feedstock. The feedstock may be fed into the system and, through exposure to a first magnetic field, isolated into a first free iron product and a first co-product. The first free iron product may continued through the system so as to further isolate into a second free iron product and a second co-product through exposure to a second magnetic field. The second free iron product may be the marketable granules of free iron product, while the first co-product and the second co-product may be combined and further isolated in the marketable non-metallic co-product.

Abstract: A 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal and its use as an opioid antagonist are disclosed. The invention also relates to a drug-in-adhesive transdermal patch containing the analgesic fentanyl, a mu opioid agonist, or an analog thereof and a 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal, as an opioid antagonist. A transdermal patch of the invention is tamper-resistant and an abuse deterrent which protects against drug misuse or abuse. The invention also provides a method of treating pain, such as acute, chronic, or intermittent pain, by applying a drug-in-adhesive transdermal patch according to the invention to the skin of a patient in need thereof. Also disclosed is an improved transdermal patch for administering fentanyl or an analog thereof, or for administering a mu opioid agonist, the improvement wherein the transdermal patch contains a 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal in an abuse limiting amount.

Abstract: The present invention is based upon the finding that certain conditions, diseases and/or disorders affecting the skin, are associated with reduced expression of an enzyme exhibiting oxidoreductase activity. Accordingly, the invention provides oxidoreductase enzymes and/or genes encoding the same for use in treating or preventing disorders of the skin and method for generating Type VII collagen suitable for use in treating disorders of the skin.