Patents by Inventor Stephen William Elson

Stephen William Elson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid
    Patent number: 6692950
    Abstract: A compound of formula (I), wherein R=H or Na, or a salt thereof and an enzyme, obtainable from Streptomyces species, having clavulanic acid dehydrogenase activity which is capable of converting (I) into clavulanic acid.
    Type: Grant
    Filed: April 3, 1996
    Date of Patent: February 17, 2004
    Assignee: SmithKline Beecham plc
    Inventors: Stephen William Elson, Neville Hubert Nicholson, Stefan Roland Woroniecki, Janice Arnell
  • Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid
    Publication number: 20030219867
    Abstract: An isolated DNA fragment encoding a protein with CAD activity wherein the protein is clavulanic acid dehydrogenase (CAD) from S. clavuligerus, with the proviso that the isolated DNA fragment is not: (a) the 13.1 kb BglII to SphI fragment of S. clavuligerus; (b) the 10.8 kb EcoRI to BamHI fragment of S. clavuligerus; (c) the 8.8 kb BclI to BclII fragment of S. clavuligerus; (d) the 2.5 kb BglII to BglII fragment of S. clavuligerus; (e) the 60 kb BglII to BamHI fragment of S. clavuligerus; or (f) the 18.0 BclI to SphI fragment of S. clavuligerus.
    Type: Application
    Filed: February 14, 2003
    Publication date: November 27, 2003
    Applicant: SmithKline Beecham plc
    Inventors: Janice Arnell, Stephen William Elson, Neville Hubert Nicholson, Stefan Roland Woroniecki
  • Process for producing clavulanic acid
    Patent number: 5869299
    Abstract: A process for preparing clavulanic acid and other clavam derivatives using an enzyme system from Streptomyces, particularly S. Clavuligerus.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: February 9, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Keith Howard Baggaley, Neville Hubert Nicholson, Stephen William Elson, Jeffrey Edwards, Alison Jane Earl, William Henry Holms, David Michael Mousdale, Jack Edward Baldwin, Christopher Schofield