Patents by Inventor Stephen Wrigley

Stephen Wrigley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYTOCHROME P450 ENZYME
    Publication number: 20240263208
    Abstract: The invention provides an enzyme with cytochrome P450 activity with mutations at the 109 and/or 198 positions based on P450SeuC10 from Streptomyces eurythermus NRRL 2539. The invention extends to related nucleic acid material and microorganisms, kits containing the enzyme, methods of producing the enzyme and methods of using the enzyme to generate oxidised organic compounds.
    Type: Application
    Filed: May 26, 2022
    Publication date: August 8, 2024
    Applicant: HYPHA DISCOVERY LTD.
    Inventors: Jonathan STEELE, Vincent POON, Stephen WRIGLEY, Emily HOPKINS, Aksana KHAN
  • Ultra-High Throughput Screening of Natural Products
    Publication number: 20100311107
    Abstract: The present invention provides cells having more than two drug resistance genes and at least two different resistance genes that have been recombined into the chromosome of a cell. It also teaches the processes for preparing cells by recombining two or more different drug resistance genes into the chromosome of a cell. The invention further shows a screening method using the cells of described herein that may be used to accomplish high throughput screening of, among other things, natural products and/or whole cells isolated from the environment.
    Type: Application
    Filed: July 27, 2010
    Publication date: December 9, 2010
    Inventors: Richard H. Baltz, Catherine Monahan, Christopher Murphy, Julia Penn, Daniel Ritz, Stephen Wrigley
  • Methods and Compositions for Ultra-High Throughput Screening of Natural Products
    Publication number: 20080318267
    Abstract: The present invention provides cells having more than two drug resistance genes and at least two different resistance genes that have been recombined into the chromosome of a cell. It also teaches the processes for preparing cells by recombining two or more different drug resistance genes into the chromosome of a cell. The invention further shows a screening method using the cells of described herein that may be used to accomplish high throughput screening of, among other things, natural products and/or whole cells isolated from the environment.
    Type: Application
    Filed: December 16, 2005
    Publication date: December 25, 2008
    Applicant: Cubist Pharmaceuticals, Inc.
    Inventors: Richard H. Baltz, Catherine Monahan, Christopher Murphy, Julia Penn, Daniel Ritz, Stephen Wrigley