Abstract: Methods and systems for monitoring and managing healthcare performance. The system comprises one or more network interfaces configured to provide access to a network and one or more data processing servers coupled to the one or more network interfaces to enable communication with one or more healthcare manager devices. The one or more data processing servers to execute instructions to receive healthcare data from a plurality of data source devices over the network, extract patient medical data from the received healthcare data, group the patient medical data according to episodes of care, analyze the patient medical data to determine variances, generate prescriptive opportunity scripts to reduce the determined variances, add the prescriptive opportunity scripts to a playbook, and generate output corresponding to the analysis and the playbook to the one or more healthcare manager devices.