Abstract: A base includes a central member adapted to rest on a flat horizontal surface. A distal handle end support member for supporting a distal handle end of a toothbrush is configured to rotate relative to the central member. An elongated member extends outward from the distal handle end support member and is fixedly connected to the distal handle end support member. A dome is connected to a distal end of the elongated member and has a completely uncovered open mouth facing the base. A resting member is positioned annularly about the elongated member for leaning the toothbrush there-against near a head of the toothbrush when the distal handle end is supported on the distal handle end support member. The dome is positioned to cover the head of the toothbrush when the distal handle end is supported on the distal handle end support member and the toothbrush is leaning against the resting member. In another embodiment, the toothbrush holder is configured to hang on a wall.