Patents by Inventor Steve Coats

Steve Coats has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-amino-quinazoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8383637
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: February 26, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Francois Paul Bischoff, Robert E. Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo D. Jordan, Chi Luo, Marc Hubert Mercken, Serge Maria Aloysius Pieters, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Brett A. Tounge, Mark J. Schulz, Hans Louis Jos De Winter
  • Tricyclic ?-opioid modulators
    Patent number: 7652005
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: January 26, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Steve Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • Tricyclic ?- opioid modulators
    Patent number: 7439239
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases and conditions, including pain. Such compounds are represented by Formula I as follows: wherein A, G, Y, R3-R5 are defined herein.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 21, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Steve Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135763
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: Steve Coats, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE)
    Publication number: 20060079687
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Application
    Filed: August 4, 2005
    Publication date: April 13, 2006
    Inventors: Ellen Baxter, Francois Bischoff, Robert Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo Jordan, Chi Luo, Marc Mercken, Serge Maria Pieters, Allen Reitz, Charles Reynolds, Tina Ross, Brett Tounge, Mark Schulz, Hans De Winter
  • Method of producing highly functionalized 1,3-diamino-propan-2-ols from solid support
    Publication number: 20050124001
    Abstract: The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.
    Type: Application
    Filed: December 7, 2004
    Publication date: June 9, 2005
    Inventors: Steve Coats, Dennis Hlasta, Mark Schulz