Patents by Inventor Steve Georas

Steve Georas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160025745
    Abstract: The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.
    Type: Application
    Filed: July 30, 2015
    Publication date: January 28, 2016
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Jia Guo, Xin Lin, Steve Georas, Patricia Sime
  • Patent number: 9107942
    Abstract: The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: August 18, 2015
    Assignee: University of Rochester
    Inventors: Jia Guo, Xin Lin, Steve Georas, Patricia Sime
  • Publication number: 20110286990
    Abstract: The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.
    Type: Application
    Filed: November 2, 2009
    Publication date: November 24, 2011
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Jia Guo, Xin Lin, Steve Georas, Patricia Sime