Patents by Inventor Steve Gerondakis

Steve Gerondakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATMENT AND AGENTS USEFUL FOR SAME
    Publication number: 20110052603
    Abstract: The present invention relates generally to a method of modulating tumor necrosis factor-mediated apoptosis and to agents useful for same. More particularly, the present invention contemplates a method of modulating tumor necrosis factor-mediated hepatocyte apoptosis by modulating an intracellular Bim and/or Bid-dependent signalling mechanism. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterized by aberrant, unwanted or otherwise inappropriate tumor necrosis factor-mediated apoptosis. The present invention is further directed to methods for identifying and/or designing agents capable of modulating the subject Bim and/or Bid-dependent signalling mechanism.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 3, 2011
    Applicant: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
    Inventors: Philippe Bouillet, Andreas Strasser, Steve Gerondakis, Fook Lin Tai, Thomas Kaufmann, Raffi Gugasyan