Abstract: Systems, media, and methods are provided to select advertisements for available impressions associated with a publisher's impression inventory. The selected advertisements may correspond to advertisement campaigns managed by buyers that seek to promote goods or services on web pages or media. The advertisement campaign is generated via an interface that receives a request for reserved or non-reserved portions of the publisher's impression inventory. The advertisement engine suggests a price for first chair access to the reserved portion or non-reserved portion via the interface. The advertisement engine selects advertisements based on the profiles of the advertisement campaigns. The profiles indicate placement preferences for advertisements and whether a portion of the impression inventory is reserved or non-reserved for the advertisement campaigns.