Patents by Inventor Steve H. Thorne

Steve H. Thorne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions concerning poxviruses and cancer
    Patent number: 8986674
    Abstract: The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: March 24, 2015
    Assignee: Sillajen Biotherapeutics, Inc.
    Inventors: David Kirn, Steve H. Thorne
  • Methods and compositions concerning poxviruses and cancer
    Patent number: 8329164
    Abstract: The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: December 11, 2012
    Assignee: Jennerex, Inc.
    Inventors: David Kirn, Steve H. Thorne
  • Methods and Compositions Concerning Poxviruses and Cancer
    Publication number: 20090004723
    Abstract: The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.
    Type: Application
    Filed: August 14, 2007
    Publication date: January 1, 2009
    Inventors: David Kirn, Steve H. Thorne