Abstract: A hand/wrist positioning splint to keep the hand positioned for radial artery access and to permit application of a hemostasis band to apply pressure to the radical artery puncture site to permit closing of said puncture site, is provided. The splint includes a rigid structure (12A) for positioning a patient's hand, and wrist in a fixed hyper-extended state, the structure (12A) having a distal end surface to support a patient's hand, and palm up, the end surface extends downwardly from the wrist position to make a first fixed angle with a horizontal plane. The rigid structure also has a wrist/forearm support surface also extending downwardly from the wrist position to make a second fixed angle with a horizontal plane. Straps (16A) are provided for securing the hand, and the wrist/forearm in fixed position on the rigid structure. An opening (20A) in the wrist/forearm surface of the rigid support below the point of arterial access permits application of a hemostasis band to the arterial puncture site.