Abstract: System and method for maintaining an organ and transporting the organ from a donor to a recipient, maintaining normothermic temperature of the organ. The system includes a circulation system providing oxygenated perfusate to the organ and enabling continuous monitoring of the perfusate moving through the organ. The tank can provide an inlet that can accept selected infusible materials, and an outlet that can enable sampling and waste removal. The system can continually monitor the solution bath in which the organ is bathed, and the system can manage the composition of the gas in the tank.