Patents by Inventor Steve Lefever

Steve Lefever has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of a lncRNA for treatment of neuroblastoma
    Patent number: 11357853
    Abstract: A treatment of cancer, particularly the treatment of neuroblastoma. Indeed, the discloses that a particular long non-coding RNA (lncRNA) is specifically up-regulated in neuroblastoma cells as compared to other cancer cells and that high expression of the lncRNA correlates with a lower survival probability. Inhibition of this lncRNA in neuroblastoma cells leads to a reduction in cell growth and induction of apoptosis and is a novel therapeutic strategy in the treatment of neuroblastoma.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: June 14, 2022
    Assignee: Universiteit Gent
    Inventors: Dries Rombaut, Pieter Mestdagh, Steve Lefever
  • INHIBITION OF A LNCRNA FOR TREATMENT OF NEUROBLASTOMA
    Publication number: 20210015921
    Abstract: A treatment of cancer, particularly the treatment of neuroblastoma. Indeed, the discloses that a particular long non-coding RNA (lncRNA) is specifically up-regulated in neuroblastoma cells as compared to other cancer cells and that high expression of the lncRNA correlates with a lower survival probability. Inhibition of this lncRNA in neuroblastoma cells leads to a reduction in cell growth and induction of apoptosis and is a novel therapeutic strategy in the treatment of neuroblastoma.
    Type: Application
    Filed: January 24, 2019
    Publication date: January 21, 2021
    Inventors: Dries Rombaut, Pieter Mestdagh, Steve Lefever