Patents by Inventor Steve Lockton

Steve Lockton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DISEASE ACTIVITY PROFILING FOR PERSONALIZED THERAPY MANAGEMENT
    Publication number: 20220096629
    Abstract: The present invention provides methods for personalized therapeutic management of a disease in order to optimize therapy and/or monitor therapeutic efficacy. In particular, the present invention comprises measuring an array of one or a plurality of biomarkers at a plurality of time points over the course of therapy with a therapeutic agent to determine a mucosal healing index for selecting therapy, optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment. In certain instances, the therapeutic agent is a TNF? inhibitor for the treatment of a TNF?-mediated disease or disorder.
    Type: Application
    Filed: September 24, 2021
    Publication date: March 31, 2022
    Inventors: Sharat Singh, Nicholas Hoe, Steve Lockton, Scott Hauenstein, Linda Ohrmund
  • Methods of disease activity profiling for personalized therapy management
    Patent number: 11160863
    Abstract: The present invention provides methods for personalized therapeutic management of a disease in order to optimize therapy and/or monitor therapeutic efficacy. In particular, the present invention comprises measuring an array of one or a plurality of biomarkers at a plurality of time points over the course of therapy with a therapeutic agent to determine a mucosal healing index for selecting therapy, optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment. In certain instances, the therapeutic agent is a TNF? inhibitor for the treatment of a TNF?-mediated disease or disorder.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: November 2, 2021
    Assignee: PROMETHEUS LABORATORIES INC.
    Inventors: Sharat Singh, Nicholas Hoe, Steve Lockton, Scott Hauenstein, Linda Ohrmund
  • METHODS OF DISEASE ACTIVITY PROFILING FOR PERSONALIZED THERAPY MANAGEMENT
    Publication number: 20190060449
    Abstract: The present invention provides methods for personalized therapeutic management of a disease in order to optimize therapy and/or monitor therapeutic efficacy. In particular, the present invention comprises measuring an array of one or a plurality of biomarkers at a plurality of time points over the course of therapy with a therapeutic agent to determine a mucosal healing index for selecting therapy, optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment. In certain instances, the therapeutic agent is a TNF? inhibitor for the treatment of a TNF?-mediated disease or disorder.
    Type: Application
    Filed: August 24, 2018
    Publication date: February 28, 2019
    Applicant: Nestec S.A.
    Inventors: Sharat Singh, Nicholas Hoe, Steve Lockton, Scott Hauenstein, Linda Ohrmund
  • Methods of disease activity profiling for personalized therapy management
    Patent number: 10086072
    Abstract: The present invention provides methods for personalized therapeutic management of a disease in order to optimize therapy and/or monitor therapeutic efficacy. In particular, the present invention comprises measuring an array of one or a plurality of biomarkers at a plurality of time points over the course of therapy with a therapeutic agent to determine a mucosal healing index for selecting therapy, optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment. In certain instances, the therapeutic agent is a TNF? inhibitor for the treatment of a TNF?-mediated disease or disorder.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: October 2, 2018
    Assignee: Nestec S.A.
    Inventors: Sharat Singh, Nicholas Hoe, Steve Lockton, Scott Hauenstein, Linda Ohrmund
  • METHODS OF DISEASE ACTIVITY PROFILING FOR PERSONALIZED THERAPY MANAGEMENT
    Publication number: 20140141983
    Abstract: The present invention provides methods for personalized therapeutic management of a disease in order to optimize therapy and/or monitor therapeutic efficacy. In particular, the present invention comprises measuring an array of one or a plurality of biomarkers at a plurality of time points over the course of therapy with a therapeutic agent to determine a mucosal healing index for selecting therapy, optimizing therapy, reducing toxicity, and/or monitoring the efficacy of therapeutic treatment. In certain instances, the therapeutic agent is a TNF? inhibitor for the treatment of a TNF?-mediated disease or disorder.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 22, 2014
    Applicant: NESTEC S.A.
    Inventors: Sharat Singh, Nicholas Hoe, Steve Lockton, Scott Hauenstein, Linda Ohrmund