Abstract: The present invention relates to a method of making a methionine preparation, for example for an animal feed additive. The invention also related to methods for increasing the solubility of a methionine preparation.

Abstract: An enzymatic synthesis and composition of oligomers and co-oligomers comprised of ?-hydroxy carboxylic acids and ?-amino acids or peptides is disclosed. In a preferred embodiment, a ?-hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a ?-amino acid specific with a specific chiral configuration or linked by an amide linkage to a peptide made up of ?-amino acid monomers having identical chiral configurations. Proteolytic enzymes catalyze oligomerization of the ?-hydroxy carboxylic acid and ?-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to animals such as ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen and other animals such as swine, poultry and aquatic animals.

Abstract: Simple, cost-effective and convenient compositions comprising basic amino acids and 2-hydroxy-4-methylthiobutanoic acid (HMBA) are disclosed. The compositions have many uses, including as food supplements for animal and human food.

Abstract: The present invention relates to a method of making a methionine preparation, for example for an animal feed additive. The invention also related to methods for increasing the solubility of a methionine preparation.