Patents by Inventor Steve Mark Harrison

Steve Mark Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mice overexpressing aspartyl protease 2 (ASP2)
    Patent number: 6958433
    Abstract: The present invention provides a recombinant DNA construct comprising a coding sequence encoding human ASP2 and a brain-specific calcium calmodulin kinase promoter sequence which is operably linked to the coding sequence. The present invention further provides a transgenic non-human animal whose genome incorporates a polynucleotide comprising a coding sequence which encodes the human ASP2 protein wherein the coding sequence is operably linked to a brain-specific calcium calmodulin kinase II promoter.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: October 25, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Martin Geppert, Alexander James Harper, Steve Mark Harrison, Haydn Prosser
  • Compounds
    Publication number: 20040154049
    Abstract: The present invention provides a recombinant DNA construct comprising a coding sequence encoding human ASP2 and a brain-specific calcium calmodulin kinase promoter sequence which is operably linked to the coding sequence. The present invention further provides a transgenic non-human animal whose genome incorporates a polynucleotide comprising a coding sequence which encodes the human ASP2 protein wherein said coding sequence is operably linked to a brain-specific calcium calmodulin kinase II promoter.
    Type: Application
    Filed: August 20, 2002
    Publication date: August 5, 2004
    Inventors: Martin Geppert, Alexander James Harper, Steve Mark Harrison, Haydn Prosser