Abstract: The present invention provides an improved process for the preparation of high purity glucagon comprising the use of Xmb-protected amino acids, wherein may Xmb include, e.g., 2,4,6-trimethoxybenzyl, 2,4-dimethoxybenzyl, or 2-hydroxy-4-methoxybenzyl. The process also comprises the use of building blocks such as pseudoprolines to avoid aggregation and obtain the product in high yield and purity.

Abstract: The present invention provides an improved process for the preparation of high purity glucagon comprising the use of Xmb-protected amino acids, wherein may Xmb include, e.g., 2,4,6-trimethoxybenzyl, 2,4-dimethoxybenzyl, or 2-hydroxy-4-methoxybenzyl. The process also comprises the use of building blocks such as pseudoprolines to avoid aggregation and obtain the product in high yield and purity.

Abstract: The present invention provides an ergonomic, rotational muscle stretching device and method for use by an individual to rehabilitate one or more muscles groups after injury or surgery, or for use by an individual for general muscle exercise purposes. The device and method allow for stretching, strengthening, and increasing flexibility of the one or more muscle groups while placing minimal stress and/or strain on associated joints due to the ability of the device to ergonomically rotate along x, y and z axes in tandem with the joints associated with the muscles being exercised, i.e., the device effectively mimics motion of the joints. This allows joints to move freely through their full range of motion so that a complete, symmetrical stretch of the exercised muscles is achieved without placing negative stress and/or strain on the joints.