Patents by Inventor Steve Paboojian
Steve Paboojian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11484671Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: GrantFiled: January 28, 2019Date of Patent: November 1, 2022Inventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Publication number: 20200197636Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: ApplicationFiled: January 28, 2019Publication date: June 25, 2020Applicant: BGP Products Operations GmbHInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Patent number: 10207066Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: GrantFiled: April 9, 2004Date of Patent: February 19, 2019Assignee: BGP Products Operations GmbHInventors: Michael John Dunkley, Jon David Tuckwell, Edward William Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Patent number: 8408200Abstract: The present invention is directed to methods and devices for delivering an active agent formulation to the lung of a human patient. The active agent formulation may be in dry powder form, it may be nebulized, or it may be in admixture with a propellant. The active agent formulation is delivered to a patient at a low inspiratory flow rate for an initial period of time to increase bioavailability of the active agent.Type: GrantFiled: October 7, 1999Date of Patent: April 2, 2013Assignee: Novartis AGInventors: Andrew Clark, Carlos Schuler, Steve Paboojian
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Publication number: 20050056275Abstract: A method for aerosolizing a powder utilizes a receptacle having a cavity containing a powder. An access end of an extraction tube is inserted into the cavity, and an inlet opening is formed in the receptacle. A pressurized gas is flowed through the inlet opening, through the cavity and through the extraction tube to move the powder in the cavity into the extraction tube where the powder is entrained in the gas to form an aerosol.Type: ApplicationFiled: December 2, 2003Publication date: March 17, 2005Inventors: Frank Ingle, Steve Paboojian, Carlos Schuler, Andrew Clark
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Publication number: 20050016533Abstract: Systems and methods are provided for aerosolizing a pharmaceutical formulation. According to one method, respiratory gases are prevented from flowing to the lungs when attempting to inhale. Then, respiratory gases are abruptly permitted to flow to the lungs. The flow of respiratory gases may then be used to extract a pharmaceutical formulation from a receptacle and to place the pharmaceutical formulation within the flow of respiratory gases to form an aerosol.Type: ApplicationFiled: June 19, 2003Publication date: January 27, 2005Applicant: Inhale Therapeutic SystemsInventors: Carlos Schuler, Steve Paboojian, Derrick Tuttle, Adrian Smith, Dennis Rasmussen, Aneesh Bakshi, Andrew Clark, Brian Ward, William Alston, Kevin Nason
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Publication number: 20050000518Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.Type: ApplicationFiled: April 9, 2004Publication date: January 6, 2005Applicant: Nektar TherapeuticsInventors: Michael Dunkley, Jon Tuckwell, Edward Vernon-Harcourt, Mark Glusker, Steve Paboojian
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Patent number: 6679256Abstract: A method for aerosolizing a powder utilizes a receptacle having a cavity containing a powder. An access end of an extraction tube is inserted into the cavity, and an inlet opening is formed in the receptacle. A pressurized gas is flowed through the inlet opening, through the cavity and through the extraction tube to move the powder in the cavity into the extraction tube where the powder is entrained in the gas to form an aerosol.Type: GrantFiled: December 6, 2000Date of Patent: January 20, 2004Assignee: Nektar TherapeuticsInventors: Frank W. Ingle, Steve Paboojian, Carlos Schuler, Andrew Clark
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Patent number: 6606992Abstract: Systems and methods are provided for aerosolizing a pharmaceutical formulation. According to one method, respiratory gases are prevented from flowing to the lungs when attempting to inhale. Then, respiratory gases are abruptly permitted to flow to the lungs. The flow of respiratory gases may then be used to extract a pharmaceutical formulation from a receptacle and to place the pharmaceutical formulation within the flow of respiratory gases to form an aerosol.Type: GrantFiled: May 30, 2000Date of Patent: August 19, 2003Assignee: Nektar TherapeuticsInventors: Carlos Schuler, Steve Paboojian, Derrick J. Tuttle, Adrian E. Smith, Dennis R. Rasmussen, Aneesh Bakshi, Andrew Clark, Brian R. S. Ward, William W. Alston, Jr., Kevin S. Nason
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Publication number: 20020168322Abstract: The present invention is directed to methods and devices for delivering an active agent formulation to the lung of a human patient. The active agent formulation may be in dry powder form, it may be nebulized, or it may be in admixture with a propellant. The active agent formulation is delivered to a patient at a low inspiratory flow rate for an initial period of time to increase bioavailability of the active agent.Type: ApplicationFiled: October 7, 1999Publication date: November 14, 2002Inventors: ANDREW CLARK, CARLOS SCHULER, STEVE PABOOJIAN
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Publication number: 20010035184Abstract: Systems and methods are provided for conditioning packaged powders. According to one method, a receptacle is provided having an enclosed chamber that contains a powder. At least one pulse of energy is applied to the receptacle to increase the efficiency at which the powder may be extracted from the chamber when flowing a gas through the chamber.Type: ApplicationFiled: December 6, 2000Publication date: November 1, 2001Inventors: Carlos Schuler, Steve Paboojian, Andrew Clark, Andrea Rourke, Joanne Curley, Don S. Minami, Derrick J. Tuttle
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Publication number: 20010029947Abstract: A receptacle for holding fine powders comprises a receptacle body that defines an enclosed cavity. The receptacle body has a top end and a bottom end. Further, the bottom end of the receptacle body includes a raised central region that extends upwardly into the cavity. In this way, the flow of air through the cavity will remain generally adjacent the walls of the cavity until exiting through an extraction tube.Type: ApplicationFiled: December 6, 2000Publication date: October 18, 2001Inventors: Steve Paboojian, Carlos Schuler, Andrew Clark
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Publication number: 20010029948Abstract: A method for aerosolizing a powder utilizes a receptacle having a cavity containing a powder. An access end of an extraction tube is inserted into the cavity, and an inlet opening is formed in the receptacle. A pressurized gas is flowed through the inlet opening, through the cavity and through the extraction tube to move the powder in the cavity into the extraction tube where the powder is entrained in the gas to form an aerosol.Type: ApplicationFiled: December 6, 2000Publication date: October 18, 2001Inventors: Frank W. Ingle, Steve Paboojian, Carlos Schuler, Andrew Clark