Abstract: A multi-modality diagnostic imaging system includes a first imaging subsystem, such as a computed tomographic (CT) system, for performing a first imaging procedure on a subject. The first imaging system has a gantry that slides along rails. A second imaging subsystem, such as a nuclear medicine system (NUC), performs a second imaging procedure on a subject. The second imaging subsystem is separate from the first imaging system, but in the same room. The second imaging subsystem has a gantry or is gantryless. A patient couch supports a subject. The patient couch is supported on a couch support having vertical adjustment and horizontally fixed. In this manner, the patient is maintained in the same position for multiple types of scans using the same couch support without horizontal translation of the patient couch and patient.