Abstract: Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/IER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.

Abstract: Example implementations may relate to methods and systems for detecting an event in a physical region within a physical space. Accordingly, a computing system may receive from a subscriber device an indication of a virtual region within a virtual representation of the physical space such that the virtual region corresponds to the physical region. The system may also receive from the subscriber a trigger condition associated with the virtual region, where the trigger condition corresponds to a particular physical change in the physical region. The system may also receive sensor data from sensors in the physical space and a portion of the sensor data may be associated with the physical region. Based on the sensor data, the system may detect an event in the physical region that satisfies the trigger condition and may responsively provide to the subscriber a notification that indicates that the trigger condition has been satisfied.

Abstract: A method includes receiving, from a subscriber device, a request including virtual region characteristics and an occupancy threshold, and determining, using image data captured by a camera and the virtual region characteristics, a virtual region corresponding to a portion of a physical region within a field of view of the camera. The virtual region is smaller than the physical region. The method also includes determining, using the image data, an occupancy of the virtual region and determining that the occupancy of the virtual region satisfies the occupancy threshold. In response to determining that the occupancy of the virtual region satisfies the occupancy threshold, the method also includes generating a notification to the subscriber device.

Abstract: Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.

Abstract: A medical system tracks the position of a portion of a medical instrument within a body of a patient. In some embodiments, the medical instrument includes a needle, a syringe, and a needle-position-tracking element positioned between the needle and the syringe and in fluid communication with both. The needle-position-tracking element includes an electromagnet structure that includes a core, a conductive coil wrapped around the core, and ancillary circuitry configured to pass a current through the conductive coil to thereby generate a magnetic field. A sensor device senses the magnetic field and generates corresponding sensor signals. A control circuit calculates the position of a portion of the medical instrument based on the sensor signals.

Abstract: An electronic control module of a light source includes at least one circuit card supporting electronic components and configured to be received by a first of its edges in a housing. The control module has in the vicinity of the first edge a connecting portion including at least one rib perpendicular or substantially perpendicular to the plane defined by the circuit card.

Abstract: An epoxy-based insulation material and a method of thermally insulating a subsea production apparatus are disclosed. The epoxy-based insulation material has an amine-cured epoxy elastomer matrix and a plurality of non-metallic beads suspended in the matrix. The epoxy-based insulation material is located on the subsea production apparatus to thermally insulate a hydrocarbon fluid from sea water.

Abstract: A medical system tracks the position of a portion of a medical instrument within a body of a patient. In some embodiments, the medical instrument includes a needle, a syringe, and a needle-position-tracking element positioned between the needle and the syringe and in fluid communication with both. The needle-position-tracking element includes an electromagnet structure that includes a core, a conductive coil wrapped around the core, and ancillary circuitry configured to pass a current through the conductive coil to thereby generate a magnetic field. A sensor device senses the magnetic field and generates corresponding sensor signals. A control circuit calculates the position of a portion of the medical instrument based on the sensor signals.

Abstract: A support structure device with an optional anti-skid/anti-tip structure is configured to assist a human patient to rise. The support structure with the optional anti-skid/anti-tip structure includes a tube bent into a shape described by way of a reference frustum such as a four-sided truncated pyramid. Each side of a top rectangular perimeter of the frustum is shorter than a corresponding side of the bottom rectangular perimeter, and each parallel side of a first trapezoidal perimeter of the frustum is shorter than a corresponding parallel side of a second trapezoidal perimeter. The anti-skid/anti-tip structure optionally includes a plurality of first coupling locations, an enclosure region, and anti-skid/anti-tip wings having anti-skid/anti-tip components.

Abstract: A support structure device is configured to assist a human patient to rise. The support structure includes a tube bent into a shape described by way of a reference frustum such as a four-sided truncated pyramid. Each side of a top rectangular perimeter of the frustum is shorter than a corresponding side of the bottom rectangular perimeter, and each parallel side of a first trapezoidal perimeter of the frustum is shorter than a corresponding parallel side of a second trapezoidal perimeter. The reference frustum has a height between 10 and 18 inches, the top rectangular perimeter has a length between 10 and 16 inches and a width between 6 and 14 inches, and the bottom rectangular perimeter has a length between 12 and 18 inches and a width between 8 and 16 inches.

Abstract: A multipart connector is employed in a system that tracks a medical device in the human body. The multipart connector includes a first connector portion and a second connector portion wherein the first connector portion pierces a contamination barrier to couple with the second connector portion. The medical device is a trackable structure having an integrated electromagnet circuit. The trackable structure is arranged to controllably produce a magnetic field. An interface is provided in the system to produce a positional representation of the trackable structure when the trackable structure is placed and moved within the human body. A magnetic field sensing device drives the integrated electromagnet circuit of the trackable structure tracks medical device and provides position information to the interface. The multipart connector electrically couples the magnetic field sensing device to the trackable structure.

Abstract: An electronic control module of a light source includes at least one circuit card supporting electronic components and configured to be received by a first of its edges in a housing. The control module has in the vicinity of the first edge a connecting portion including at least one rib perpendicular or substantially perpendicular to the plane defined by the circuit card.

Abstract: A support structure device is configured to assist a human patient to rise. The support structure includes a tube bent into a shape described by way of a reference frustum such as a four-sided truncated pyramid. Each side of a top rectangular perimeter of the frustum is shorter than a corresponding side of the bottom rectangular perimeter, and each parallel side of a first trapezoidal perimeter of the frustum is shorter than a corresponding parallel side of a second trapezoidal perimeter. The reference frustum has a height between 10 and 18 inches, the top rectangular perimeter has a length between 10 and 16 inches and a width between 6 and 14 inches, and the bottom rectangular perimeter has a length between 12 and 18 inches and a width between 8 and 16 inches.

Abstract: A housing for a lighting device, in particular for a motor vehicle, comprising a wall delimiting a cavity designed to receive one or more lighting modules, and an edge that delimits the cavity and is designed to be glued to a corresponding rim of an outer lens designed to cover the cavity. The edge has at least one portion with ribs that are designed to be in contact with the glue and are oriented such as to limit the flow of the glue during application of same. The invention also relates to a lighting device including the housing, and to a method for assembling the device.

Abstract: An epoxy-based insulation material and a method of thermally insulating a subsea production apparatus are disclosed. The epoxy-based insulation material has an amine-cured epoxy elastomer matrix and a plurality of non-metallic beads suspended in the matrix. The epoxy-based insulation material is located on the subsea production apparatus to thermally insulate a hydrocarbon fluid from sea water.

Abstract: An endoscopic device having a one-handed, either-handed steering mechanism is presented. The endoscopic device includes some components that are sterile and used on only a single patient. The single-use components are medically disposed of after exposure to a non-sterile environment such as an internal body cavity of a patient. The endoscopic device also includes some reusable components that are not exposed to a non-sterile environment.

Abstract: An endoscopic device has a tubular body with a retention channel substantially extending axially along the tube body. A medical tube is removably arranged in the retention channel and held in place by friction. A cable assembly is arranged between the medical tube and the surface of the retention channel. The cable assembly includes a shaped end fixture that is drawn between the medical tube and the retention channel when the cable is pulled, thereby releasing the medical tube from the tube body.

Abstract: The invention is directed toward a magnetic valve reader used as an indicator tool. The magnetic valve reader determines a location and an orientation for a magnetic indicator device to indicate a device setting of an implantable medical device. The implantable medical device includes the magnetic indicator device coupled to a valve on the implantable medical device. External magnetic fields, specifically the Earth's magnetic field, may interfere with the compass and create an incorrect device setting indication. The electronic reader estimates the external magnetic fields to subtract the estimate from received data to minimize any influence that external magnetic field has on the accuracy of the device setting measurement.

Abstract: The invention is directed toward a magnetic valve reader used as an indicator tool. The magnetic valve reader determines a location and an orientation for a magnetic indicator device to indicate a device setting of an implantable medical device. The implantable medical device includes the magnetic indicator device coupled to a valve on the implantable medical device. External magnetic fields, specifically the Earth's magnetic field, may interfere with the compass and create an incorrect device setting indication. The electronic reader estimates the external magnetic fields to subtract the estimate from received data to minimize any influence that external magnetic field has on the accuracy of the device setting measurement.

Abstract: The invention is directed toward a magnetic valve reader used as an indicator tool. The magnetic valve reader determines a location and an orientation for a magnetic indicator device to indicate a device setting of an implantable medical device. The implantable medical device includes the magnetic indicator device coupled to a valve on the implantable medical device. External magnetic fields, specifically the Earth's magnetic field, may interfere with the compass and create an incorrect device setting indication. The electronic reader estimates the external magnetic fields to subtract the estimate from received data to minimize any influence that external magnetic field has on the accuracy of the device setting measurement.