Patents by Inventor Steve Wu
Steve Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945181Abstract: Described herein is a method for producing photochromic silicone hydrogel contact lenses in a relatively efficient and consistent manner from a polymerizable composition under a controlled thermal curing scheme. The main polymerizable components in the polymerizable composition are a high radical-reactive hydrophilic (meth)acrylamido monomer, a high radical-reactive siloxane-containing (meth)acrylamido monomer, and a polysiloxane vinylic crosslinker(s) free of low-reactive ethylenically unsaturated group as the main crosslinker. The thermal free radical initiator having a 10 hour half-life temperature (T10h?) of from about 50° C. to about 90° C. The controlled thermal curing scheme includes maintaining a first curing temperature of from about (T10h??20)° C. to about T10h?° C. for a first curing time and maintaining a second curing temperature of from about (T10h?+10)° C. to about (T10h?+35)° C. for a second curing time.Type: GrantFiled: October 27, 2021Date of Patent: April 2, 2024Assignee: Alcon Inc.Inventors: Junhao Ge, Yuan Chang, Steve Yun Zhang, Michelle Plavnik, Augustine Twum Kumi, Daqing Wu
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Publication number: 20240091403Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.Type: ApplicationFiled: November 15, 2023Publication date: March 21, 2024Inventors: Gregory M. Cruise, Steve Plotkin, Xinping Wu
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Patent number: 11931454Abstract: The invention is generally related to a soft hydrogel ocular insert that is composed of at least one hydrogel material in fully hydrated state and can be comfortable for wearing. The hydrogel material comprises polymer chains, which are derived from at least one arylborono-containing hydrophilic copolymer and at least one mucoadhesive polymer, and cyclic boronic ester crosslinks for crosslinking those mucoadhesive polymer chains and arylborono-containing hydrophilic copolymer chains to form a 3-dimensional polymer network. Those cyclic boronic ester crosslinks can be hydrolyzed slowly in the tear of the eyes of a patient, resulting in the disintegration (dissolution) of the 3-dimensional polymer network and thereby providing mucoadhesisve polymers and optionally drugs impregnated in the hydrogel ocular insert in a controlled manner.Type: GrantFiled: September 17, 2020Date of Patent: March 19, 2024Assignee: Alcon Inc.Inventors: Junhao Ge, Steve Yun Zhang, Daqing Wu, Jing Cheng
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Patent number: 11912727Abstract: Disclosed are compounds of formula (Ia) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (Ia) and methods of using the same for treating cancer or a respiratory inflammatory disease and inhibiting arginase: wherein R1 is —NHR1a; R1a is —H or —C(O)CH(R1b)NHR1c; and R1b is selected from —H, —(C1-C4) alkyl and CH2OR1d and R1c is —H; or R1b and R1c, together with the atom to which they are attached, form a 5-membered heterocyclic ring; and R1d is H or —CH3.Type: GrantFiled: July 10, 2023Date of Patent: February 27, 2024Assignee: AstraZeneca ABInventors: Scott Nathan Mlynarski, Tyler Grebe, Sameer Kawatkar, Maurice Raymond Verschoyle Finlay, Iain Simpson, Jianyan Wang, Steve Cook, Dedong Wu
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Patent number: 11688826Abstract: A light emitting device, a method of fabricating a light emitting device and a method of controlling light emission. The light emitting device includes a plasmonic structure. The plasmonic structure is configured to have a plurality of localized surface plasmon resonances. The light emitting device also includes a broadband light emitting layer having an emission spectrum substantially overlapping wavelengths of the localized surface plasmon resonances. A spacer layer is disposed between the plasmonic structure and the broadband light emitting layer. A color of light emitted by the broadband light emitting layer is tunable by the localized surface plasmon resonances of the plasmonic structure.Type: GrantFiled: June 5, 2018Date of Patent: June 27, 2023Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Ee Jin Teo, Yi Shi, Chengyuan Yang, Qing Yang Steve Wu, Yin Thai Chan, Yang Xu, Chi Jin Darren Neo
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Publication number: 20220093810Abstract: A device which detects and/or emits infrared radiation in the mid-infrared to far- infrared region is disclosed herein. The device comprises a first layer comprising a first transition metal dichalcogenide, and a second layer comprising a second transition metal dichalcogenide, wherein the second layer is deposited adjacent to the first layer to form a first interface which interlayer excitons are producible from for rendering the device operable to detect and/or emit infrared radiation in the mid-infrared to far-infrared region.Type: ApplicationFiled: December 16, 2019Publication date: March 24, 2022Inventors: Steven LUKMAN, Jinghua TENG, Qing Yang Steve WU, Lu DING
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Publication number: 20220015785Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: ApplicationFiled: June 29, 2021Publication date: January 20, 2022Inventors: Doug HAKALA, John M. ADAMS, Khoi T. LE, Show-Mean Steve WU
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Patent number: 11076874Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: GrantFiled: January 4, 2019Date of Patent: August 3, 2021Assignee: Shockwave Medical, Inc.Inventors: Doug Hakala, John M. Adams, Khoi T. Le, Show-Mean Steve Wu
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Publication number: 20200203560Abstract: A light emitting device, a method of fabricating a light emitting device and a method of controlling light emission. The light emitting device includes a plasmonic structure. The plasmonic structure is configured to have a plurality of localized surface plasmon resonances. The light emitting device also includes a broadband light emitting layer having an emission spectrum substantially overlapping wavelengths of the localized surface plasmon resonances. A spacer layer is disposed between the plasmonic structure and the broadband light emitting layer. A color of light emitted by the broadband light emitting layer is tunable by the localized surface plasmon resonances of the plasmonic structure.Type: ApplicationFiled: June 5, 2018Publication date: June 25, 2020Inventors: Ee Jin Teo, Yi Shi, Chengyuan Yang, Qing Yang Steve Wu, Yin Thai Chan, Yang Xu, Chi Jin Darren Neo
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Publication number: 20190269426Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: ApplicationFiled: January 4, 2019Publication date: September 5, 2019Applicant: Shockwave Medical, Inc.Inventors: Doug HAKALA, John M. M. ADAMS, Khoi T. LE, Show-Mean Steve WU
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Patent number: 10206698Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: GrantFiled: July 27, 2016Date of Patent: February 19, 2019Assignee: SHOCKWAVE MEDICAL, INC.Inventors: Doug Hakala, John M. Adams, Khoi T. Le, Show-Mean Steve Wu
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Patent number: 9935355Abstract: A THz photomixer emitter is disclosed. The emitter comprises a photoconductive material, an antenna structure, and an electrode array. The electrode array is disposed such that an electric field associated with photocarriers generated in the photoconductive material is coupled to the antenna for emission of a THz wave via the antenna structure. The electrode array is configured such that an electric field resonance pattern of the electrode array is substantially aligned with an emission field pattern of the antenna structure.Type: GrantFiled: October 28, 2011Date of Patent: April 3, 2018Assignee: Agency for Science, Technology and ResearchInventors: Jinghua Teng, Hendrix Tanoto, Qing Yang Steve Wu
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Patent number: 9675137Abstract: An elastic coreless rope belt is a tubular braided rope of no core with stretch elasticity. Wherein the center part of the elastic rope belt along its length keep the same hollow shape, and at the periphery of the rope, it is provided with protruded knot parts of plural middle segment. At the plural middle segment, the diameter of the protruded knot can be changed with the changing of the axial tension. Once the axial tension is relived, the diameter and the shape will return to the origin. Thereby, it is convenient to make position limited buckling and loosening to the object hole.Type: GrantFiled: September 8, 2015Date of Patent: June 13, 2017Inventor: Steve Wu
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Publication number: 20170065026Abstract: An elastic coreless rope belt is a tubular braided rope of no core with stretch elasticity. Wherein the center part of the elastic rope belt along its length keep the same hollow shape, and at the periphery of the rope, it is provided with protruded knot parts of plural middle segment. At the plural middle segment, the diameter of the protruded knot can be changed with the changing of the axial tension. Once the axial tension is relived, the diameter and the shape will return to the origin. Thereby, it is convenient to make position limited buckling and loosening to the object hole.Type: ApplicationFiled: September 8, 2015Publication date: March 9, 2017Inventor: Steve Wu
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Publication number: 20160331389Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: ApplicationFiled: July 27, 2016Publication date: November 17, 2016Inventors: Doug HAKALA, John M. ADAMS, Khoi T. LE, Show-Mean Steve WU
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Patent number: 9433428Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: GrantFiled: October 15, 2014Date of Patent: September 6, 2016Assignee: Shockwave Medical, Inc.Inventors: Doug Hakala, John M. Adams, Khoi T. Le, Show-Mean Steve Wu
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Publication number: 20160135828Abstract: Described here are devices and methods that may facilitate treatment of a calcified heart valve with shock waves. A shock wave valvuloplasty device may be advanced through a patient's vasculature and self-align with cusps of a calcified aortic valve. Alignment may be facilitated by a central anchor and/or U-shaped distal bends of positioning wires. An elongated carrier may be slidably disposed over a portion of the positioning wire and carry one or more electrode assemblies that may generate shock waves. An inflatable balloon may sealably enclose the electrode assembles, and shock waves may propagate through the liquid-filled balloon and transfer energy to adjacent calcified valve cusps. The shock wave valvuloplasty device may comprise one or more features to direct shock waves to specific areas of calcified tissue. Some variations also comprise a central anchor configured to be positioned below the valve leaflets.Type: ApplicationFiled: November 12, 2015Publication date: May 19, 2016Inventors: Daniel HAWKINS, Mark C. T. HUANG, Show-Mean Steve WU, Arnel CASTRO, Rainier BETELIA, Adam R. TANNER
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Publication number: 20150355458Abstract: The present disclosure provides a micro-machined switchable optical mirror device with a fast response speed. The mirror device includes a substrate defining a gap space, and a mirror assembly disposed on the substrate and deflectable in the gap space, the mirror assembly including a free end cantilever and a reflector on the cantilever, wherein the cantilever is anchored on the substrate adjacent a side of the gap space through an elastic member. In one aspect, the mirror device further includes a stop spring at an end of the cantilever opposing the elastic member.Type: ApplicationFiled: June 10, 2014Publication date: December 10, 2015Inventors: Shuyun (Steve) Wu, Jing Zhao
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Publication number: 20150073430Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: ApplicationFiled: October 15, 2014Publication date: March 12, 2015Inventors: Doug HAKALA, John M. ADAMS, Khoi T. LE, Show-Mean Steve WU
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Patent number: 8888788Abstract: Described herein are low-profile electrodes for use with an angioplasty shockwave catheter. A low-profile electrode assembly may have an inner electrode, an insulating layer disposed over the inner electrode such that an opening in the insulating layer is aligned with the inner electrode, and an outer electrode sheath disposed over the insulating layer such that an opening in the outer electrode sheath is coaxially aligned with the opening in the insulating layer. This layered configuration allows for the generation of shockwaves that propagate outward from the side of the catheter. In some variations, the electrode assembly has a second inner electrode, and the insulating layer and outer electrode may each have a second opening that are coaxially aligned with the second inner electrode. An angioplasty shockwave catheter may have a plurality of such low-profile electrode assemblies along its length to break up calcified plaques along a length of a vessel.Type: GrantFiled: March 14, 2013Date of Patent: November 18, 2014Assignee: Shockwave Medical, Inc.Inventors: Doug Hakala, John M. Adams, Khoi T. Le, Show-Mean Steve Wu