Patents by Inventor Steven A. Bradley

Steven A. Bradley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20010036949
    Abstract: A pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal comprising administration of a nicotine receptor partial agonist or a pharmaceutically acceptable salt thereof; and an acetylcholinesterase inhibitor, butylcholinesterase inhibitor, an estrogenic agent, selective estrogen receptor modulator or muscarinic agonist or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier. The nicotine receptor partial agonist and acetylcholinesterase inhibitor, butylcholinesterase inhibitor, estrogen, selective estrogen receptor modulator or muscarinic agonist are present in amounts that render the composition effective enhancing cognition or in the treatment of diseases of cognitive dysfunction including but not limited to Alzheimer's Disease, mild cognitive impairment, age-related cognitive decline, vascular dementia, Parkinson's disease dementia, Huntington's Disease, Stroke, TBI, AIDS associated dementia and schizophrenia.
    Type: Application
    Filed: January 16, 2001
    Publication date: November 1, 2001
    Inventors: Jotham Wadsworth Coe, Steven Bradley Sands, Edmund Patrick Harrigan, Brian Thomas O'Neill, Eric Jacob Watsky
  • Patent number: 6013474
    Abstract: Calcium channel (alpha).sub.1 -subunit and (alpha).sub.2 -subunit-encoding DNA, and related compositions and methods, are provided.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: January 11, 2000
    Assignee: Sibia Neurosciences, Inc.
    Inventors: Steven Bradley Ellis, Mark E. Williams, Michael Miller Harpold, Arnold Schwartz, Robert Brenner
  • Patent number: 5981193
    Abstract: Human neuronal nicotinic acetylcholine receptor subunits are described, as are methods for producing cells containing functional receptors employing such subunits. Also described are assay methods for determining the presence of functional HnAChRs in transfected cells, and for determining the agonist or antagonist activity of compounds with respect to such cells.
    Type: Grant
    Filed: November 30, 1992
    Date of Patent: November 9, 1999
    Assignee: Sibia Neurosciences, Inc.
    Inventors: Michael Miller Harpold, Steven Bradley Ellis, Paul Brust, Michael Akong, Gonul Velicelebi
  • Patent number: 5726035
    Abstract: Calcium channel .gamma.-subunit-encoding cDNAs, and related compositions and methods, are provided.
    Type: Grant
    Filed: November 7, 1994
    Date of Patent: March 10, 1998
    Assignees: SIBIA Neurosciences, Inc., University of Iowa Research Foundation
    Inventors: Scott David Jay, Steven Bradley Ellis, Michael Miller Harpold, Kevin Peter Campbell
  • Patent number: 5710250
    Abstract: .alpha..sub.1 - and .alpha..sub.2 - protein subunits of voltage-dependent calcium channels are provided.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: January 20, 1998
    Assignee: SIBIA Neurosciences, Inc.
    Inventors: Steven Bradley Ellis, Mark E. Williams, Michael Miller Harpold, Jean Sartor, Robert Brenner
  • Patent number: 5686241
    Abstract: Calcium channel (alpha).sub.1 -subunit and (alpha).sub.2 -subunit-encoding DNA, and related compositions and methods, are provided.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: November 11, 1997
    Assignee: Sibia Neurosciences, Inc.
    Inventors: Steven Bradley Ellis, Mark E. Williams, Michael Miller Harpold, Arnold Schwartz, Robert Brenner
  • Patent number: 5461016
    Abstract: Reforming selective for the dehydrocyclization of paraffins to aromatics, is effected using a catalyst containing a platinum-group metal, a nonacidic large-pore molecular sieve, and a metal modifier which is positioned on the catalyst to be extrinsic to the pores of the molecular sieve. The use of this catalyst results in greater selectivity converting paraffins to aromatics and improved catalyst stability particularly when processing feedstocks containing small amounts of sulfur compounds.
    Type: Grant
    Filed: August 17, 1994
    Date of Patent: October 24, 1995
    Assignee: UOP
    Inventors: Steven A. Bradley, Leonid B. Galperin
  • Patent number: 5439864
    Abstract: This invention relates to a shaped composition composed of a carbonaceous pyropolymer having recurring units containing at least carbon and hydrogen atoms. The composition is characterized by a crush strength of at least 6 kg and has a bimodal pore distribution having maxima at pore diameters of about 60 to 900 .ANG. and about 120 to 160 .ANG..
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: August 8, 1995
    Assignee: UOP
    Inventors: Richard R. Rosin, Steven A. Bradley
  • Patent number: 5366617
    Abstract: A reforming process, selective for the dehydrocyclization of paraffins to aromatics, is effected using a catalyst containing a platinum-group metal, a nonacidic large-pore molecular sieve, and a metal modifier which is positioned on the catalyst to be extrinsic to the pores of the molecular sieve. The use of this catalyst results in greater selectivity converting paraffins to aromatics and improved catalyst stability particularly when processing feedstocks containing small amounts of sulfur compounds.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: November 22, 1994
    Assignee: UOP
    Inventors: Steven A. Bradley, Leonid B. Galperin
  • Patent number: 5170673
    Abstract: Fume hood controller apparatus includes a computing means, together with associated memory, which can be configured for horizontally and/or vertically moveable sash doors by inputting the necessary dimensions of the sash doors and other structural features, such as the upper lip height, frame widths and the like. The apparatus rapidly calculates the size of the uncovered area of the fume hood as a functions of the position of the sash doors.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: December 15, 1992
    Assignee: Landis & Gyr Powers, Inc.
    Inventors: Osman Ahmed, Steven A. Bradley, Steven L. Fritsche
  • Patent number: 5115728
    Abstract: A system whereby the pressure of a room containing one or more fume hoods, such as a laboratory, is to maintained at a predetermined level relative to the pressure of a reference space in the building, which may be the pressure in an adjacent corridor or an adjacent room or the like. The system involves a room controller which is part of the heating, ventilating and air conditioning apparatus of the building. The room controller is of the type which can receive electrical signals from each fume hood controller, which signals are proportional to the volume of air that is being exhausted through each fume hood. The volume indicating signals communicated from each of the fume hood controllers to the room controller enable the system to modulate the volume of air that is being supplied to the room and thereby maintain the differential pressure at the desired level with relatively quick response times.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: May 26, 1992
    Assignee: Landis & Gyr Powers, Inc.
    Inventors: Osman Ahmed, Steven A. Bradley
  • Patent number: 5092227
    Abstract: Apparatus for controlling the air flow through a fume hood to maintain a predetermined average face velocity through an uncovered portion of an opening of a fume hood of the type which has at least one movable sash door adapted to cover the opening as the fume hood sash door is moved. The apparatus detects the position of each moveable sash door and calculates the size of the uncovered portion of the opening, measures the actual flow of air through the exhaust duct, and varies the flow of air through the exhaust duct responsive to door position signals and the actual flow signal for controlling a flow modulating means to maintain the predetermined average face velocity through the uncovered portion of the opening.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: March 3, 1992
    Assignee: Landis & Gyr Powers, Inc.
    Inventors: Osman Ahmed, Steven A. Bradley, Steven L. Fritsche, Steven D. Jacob
  • Patent number: 4485153
    Abstract: Conductive thick film pigment-coated surfaces which possess desirable conductivity and solderability characteristics are formed from an alloy comprising a mixture of a nonnoble conductive metal, a noble metal and at least one oxidizable material. The oxidizable material is present in the alloy in an amount in the range of from about 5% to about 25% by weight, the nonnoble metal in an amount in the range of from about 94% to about 60% by weight and the noble metal in an amount in the range of from about 1% to about 15% by weight of the alloy. The desired product is prepared by admixing a nonnoble metal, an oxidizable material and a noble metal, arc-melting the mixture to form an alloy, grinding the arc-melted alloy to a powdered form, admixing the powder with the carrier binder, depositing said admixture on an inert surface, firing the admixture and surface in an oxygen-containing atmosphere at a temperature in the range of from about 500.degree. to about 950.degree. C.
    Type: Grant
    Filed: April 30, 1984
    Date of Patent: November 27, 1984
    Assignee: UOP Inc.
    Inventors: Daniel S. Janikowski, Steven A. Bradley
  • Patent number: 4388347
    Abstract: Conductive pigment-coated surfaces may be prepared by alloying a nonnoble conductive metal with an oxidizable material, admixing the alloy with an organic vehicle and a binder to form an ink followed by firing the ink in an oxidizing atmosphere containing about 20% by volume of oxygen at a temperature in excess of 1000.degree. F. If so desired, a vitreous frit may also be present in the mixture. The resulting ink will possess desirable characteristics such as increased resistivity to oxidation, and increased firing strength when the oxidizable material such as boron is present in the alloy in an amount in the range of from about 12% to about 25% by weight.
    Type: Grant
    Filed: May 17, 1982
    Date of Patent: June 14, 1983
    Assignee: UOP Inc.
    Inventors: Ming S. Shum, Daniel S. Janikowski, Steven A. Bradley
  • Patent number: 4246057
    Abstract: The invention relates to improving the heat transfer properties in boiling liquids of tubes and other surfaces by applying a very porous reticulated organic foam layer in contact with the tube surface, and then plating a thin metal coating on the foam substrate. Preferably, the tube is copper and the plating consists of a first electrolessly applied layer of copper and a second electroplated layer. The foam is preferably in the form of a thin tape which is spirally wound about the tube. Pyrolization of the foam after plating improves the heat transfer performance of the tube.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: January 20, 1981
    Assignee: UOP Inc.
    Inventors: Kenneth R. Janowski, Ming S. Shum, Steven A. Bradley
  • Patent number: 4129181
    Abstract: The invention relates to improving the heat transfer properties in boiling liquids of tubes and other surfaces by applying a very porous reticulated organic foam layer in contact with the tube surface, and then plating a thin metal coating on the foam substrate. Preferably, the tube is copper and the plating consists of a first electrolessly applied layer of copper and a second electroplated layer. The foam is preferably in the form of a thin tape which is spirally wound about the tube. Pyrolization of the foam after plating improves the heat transfer performance of the tube.
    Type: Grant
    Filed: February 16, 1977
    Date of Patent: December 12, 1978
    Assignee: UOP Inc.
    Inventors: Kenneth R. Janowski, Ming S. Shum, Steven A. Bradley
  • Patent number: 4079156
    Abstract: Conductive metal pigments which may be used in electrical devices are prepared by forming an alloy of a non-noble conductive metal and at least one oxidizable material, mixing the resulting alloy with a vitreous frit and an organic vehicle to form an ink, screening said ink onto a substrate, firing the alloy in an air atmosphere at a temperature in excess of about 500.degree. C. and cooling the ink to produce a conductive pigment. The oxidizable material is preferentially oxidized during the firing with a concomitant non-oxidation of the non-noble conductive metal.
    Type: Grant
    Filed: July 19, 1976
    Date of Patent: March 14, 1978
    Assignee: UOP Inc.
    Inventors: Karl J. Youtsey, Steven A. Bradley