Abstract: A method is provided for preparing a tissue implant for implantation. The method includes treating a pericardium tissue material, which has been harvested from a donor and rendered essentially acellular, with a chlorine dioxide treatment solution; and thereafter treating the pericardium tissue material with an antioxidant solution, which comprises ascorbic acid or a salt thereof.

Abstract: A method for administering an audio message to a user of an earpiece can include receiving event information from a paired communication device, updating a personal event calendar by ordering event information to generate a first event list, generating a modified event list by grouping events in the first event list according to acceptance criteria based on event priority of event types, and generating an audio token for collective events in the modified event list for audible delivery to the ear canal. Events can be ordered by event name, event location, event data, event importance, event invitees, or event category.

Abstract: An earpiece can include an Ambient Sound Microphone (ASM), an Ear Canal Receiver (ECR), a transceiver, an illumination element, and a processor to provide visual operational mode indication via the illumination element. The operational mode can correspond to an active phone call, an incoming phone call, a terminated phone, a caller-on-hold condition, a recording mode, a voice mail mode, a mute mode, an audible transparency mode or an ear-plug mode. The intensity, frequency, amplitude, color or duration of the lighting can be adjusted according to the operational mode.

Abstract: A system and method for accessing and utilizing ancillary data with an electronic camera device includes a data source that stores various selectable ancillary data files such as image template files, text overlay files, image background files, and special program instruction files. The data source may be implemented in any effective manner, including as a service on an distributed computer network like the Internet, as a discrete electronic device such as a personal computer, or as a removable, non-volatile memory device such as a flash memory. The electronic camera device may then utilize an ancillary data module to access, select, and download the ancillary data files from the data source for subsequently combining with other captured image data to thereby produce new composite images.

Abstract: An earpiece is provided containing a thermal activator layer comprised of a first polymer, the thermal activator layer being separated from the tympanic membrane of the user's ear by an air gap, and an acoustical reflector layer, containing a second polymer and pigment particles, adjacent to the thermal activator layer. The earpiece may be produced by sequential introduction of various liquefied components in layers within the ear canal, with the components being cured to provide the thermal activator layer and the acoustical reflector layer.

Abstract: In a method for diagnosing or helping to diagnose a bone tissue condition of a patient, a portion of bone tissue of the patient is irradiated using a light source. The bone tissue may be irradiated in vivo through the skin or via an incision, for example. Alternatively, a biopsy of the bone tissue may be irradiated. Then, spectral content information for light scattered, reflected, or transmitted by the bone tissue is determined, and is used, at least in part, to determine whether the patient has a bone tissue condition.

Abstract: Earpieces and methods for an earpiece to manage a delivery of a message are provided. A method can include receiving a notice that a message is available at a communication device, parsing the notice for header information that identifies at least a portion of the message, and requesting a subsequent delivery of at least a portion of the message from the communication device if at least one keyword in the header information is in an acceptance list.

Abstract: A method to automatically adjust listening levels to safe listening levels is provided. The method can include the steps of monitoring an audio content level, monitoring a sound pressure level within an ear canal, and gradually reducing over time a volume of the audio content responsive to detecting intermittent manual volume increases of the audio content.

Abstract: The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of interest. The invention is based on the discovery that mammalian repair cells proliferate and migrate into a wound site where they actively take up and express DNA. The invention further relates to pharmaceutical compositions that may be used in the practice of the invention to transfer the DNA of interest. Such compositions include any suitable matrix in combination with the DNA of interest.

Abstract: A method is provided for preparing a tissue implant for implantation. The method includes harvesting a tissue material from a human or an animal donor, treating the tissue material with water or a hypotonic solution to lyse native cells of the tissue material, treating the tissue material in a nuclease-containing solution which includes an antimicrobial, treating the tissue material with an alkaline alcohol solution, treating the tissue material with a chlorine dioxide treatment solution, and sterilizing the tissue material.

Abstract: A method is provided for preparing a tissue implant for implantation. The method includes treating a pericardium tissue material, which has been harvested from a donor and rendered essentially acellular, with a chlorine dioxide treatment solution; and thereafter treating the pericardium tissue material with an antioxidant solution, which comprises ascorbic acid or a salt thereof.

Abstract: An earpiece is provided containing a thermal activator layer comprised of a first polymer, the thermal activator layer being separated from the tympanic membrane of the user's ear by an air gap, and an acoustical reflector layer, containing a second polymer and pigment particles, adjacent to the thermal activator layer. The earpiece may be produced by sequential introduction of various liquefied components in layers within the ear canal, with the components being cured to provide the thermal activator layer and the acoustical reflector layer.

Abstract: Methods and systems are provided which generate an alarm signal that alerts individuals who may be in the vicinity of a reversing vehicle and that alerts a vehicle operator when the alarm signal is not audible due to high ambient sound levels or detritus covering the alarm transducer. A background noise level in proximity to the vehicle is monitored. A level of the alarm signal is increased as the ambient (or background) sound level rises. Conversely, the level of the alarm signal is reduced as the background noise level decreases. The alarm signal is changed in volume, frequency, or both based on a velocity of the vehicle. A frequency content of the alarm signal may be modified if a spectral profile of an ambient sound field contains spectral components that may mask the alarm signal.

Abstract: The disclosure relates to a method and system of screening for ligands which specifically bind to receptors. The method comprises expressing at least one receptor. The at least one receptor is contacted with a sample comprising at least one ligand. Whether the ligand selectively binds to the receptor is determined.

Abstract: A method of preparing a tissue graft material is disclosed. The disclosure also relates to a multipurpose tissue graft material and to methods of using same as a replacement for vascular and non-vascular tissue.

Abstract: At least one exemplary embodiment is directed to a method of generating a Personalized Audio Content (PAC) comprising: selecting Audio Content (AC) to personalize; selecting an Earprint; and generating a PAC using the Earprint to modify the AC.

Abstract: The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of interest. The invention is based on the discovery that mammalian repair cells proliferate and migrate into a wound site where they actively take up and express DNA. The invention further relates to pharmaceutical compositions that may be used in the practice of the invention to transfer the DNA of interest. Such compositions include any suitable matrix in combination with the DNA of interest.

Abstract: The present invention relates to a method of preparing a tissue graft material. The invention also relates to a multipurpose tissue graft material and to methods of using same as a replacement for vascular and non-vascular tissue.

Abstract: At least one exemplary embodiment is directed to a website configured to collect sound signatures from around the world and beyond. A communication device automatically stores acoustic information received by a microphone of the communication device. The acoustic information is analyzed for a trigger event. The trigger event stores the acoustic information, attaches metadata, creates a Gaussian Mixture Model, and measures sound pressure level. The communication device automatically sends the sound signature to a database when a communication path is opened to communication device. Each sound signature has associated metadata including a time stamp and geocode. Automatically collecting sounds using a communication device adapted for the process enables a database that captures sounds globally on a continuous basis.

Abstract: A method for using an earpiece (800) in a work environment is provided. The earpiece (800) attenuates sound from the work environment to the user's ear. The earpiece (800) includes an ear canal microphone (820) for measuring a sound pressure level in an ear canal of the user. Sound pressure levels are measured periodically while in the work environment. Each measured sound pressure levels is stored in memory (127) of the earpiece with time and location information. The sound pressure level information is downloaded to a database (1704) when the earpiece is removed from the user ear for recharging. The sound pressure level information is analyzed and any potential noise compliance issues in the work environment are identified.