Patents by Inventor Steven A. Jacobs

Steven A. Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160259491
    Abstract: A method for enabling a third party to dynamically reskin information displayed at a primary user device associated with a user account includes: transmitting a user interface template to a third party device, receiving assets from the third party device, delivering a bundle to a user device, and presenting the user interface based on the bundle.
    Type: Application
    Filed: March 2, 2016
    Publication date: September 8, 2016
    Inventors: Steven Jacobs, Evan Wilson, Michael Smith
  • Publication number: 20160244744
    Abstract: A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof, exhibit enhanced thermal and chemical stability while presenting six modifiable loop domains which can be engineered to form a binding partner capable of binding to a target for applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: December 15, 2015
    Publication date: August 25, 2016
    Inventor: Steven Jacobs
  • Publication number: 20160146869
    Abstract: Embodiments of the invention include methods and devices for determining a phase angle offset between a phase angle of a local oscillator relative to a phase angle of a signal input of a Device Under Test (DUT). Some embodiments include a laser source and an optical phase adjustor, which may be embodied by a loop stretcher structured to controllably stretch a length of fiber optic cable, driven by a phase adjust driver. In other embodiments the phase angle offset information is conveyed to an oscilloscope for internal compensation.
    Type: Application
    Filed: November 18, 2015
    Publication date: May 26, 2016
    Inventors: Robert A. Marsland, JR., Steven A. Jacobs
  • Publication number: 20160083436
    Abstract: Non-natural albumin binding domains, polynucleotides encoding thereof and methods of making and using these domains and polynucleotides are useful in controlling the half-life of therapeutic molecules for patients.
    Type: Application
    Filed: September 1, 2015
    Publication date: March 24, 2016
    Inventor: Steven Jacobs
  • Publication number: 20160041182
    Abstract: Protein scaffolds and scaffold libraries based on a fibronectin type III (FN3) repeat with an alternative binding surface design, isolated nucleic acids encoding the protein scaffolds, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
    Type: Application
    Filed: August 10, 2015
    Publication date: February 11, 2016
    Inventors: Michael Diem, Steven Jacobs
  • Publication number: 20160039909
    Abstract: A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.
    Type: Application
    Filed: October 23, 2015
    Publication date: February 11, 2016
    Inventors: Steven Jacobs, Karyn O'Neil
  • Patent number: 9234029
    Abstract: A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof, exhibit enhanced thermal and chemical stability while presenting six modifiable loop domains which can be engineered to form a binding partner capable of binding to a target for applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: January 12, 2016
    Assignee: Janssen Biotech, Inc.
    Inventor: Steven Jacobs
  • Patent number: 9206244
    Abstract: IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: December 8, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Michael Baumann, Gaby Tresch, Steven Jacobs, Karyn O'Neil
  • Patent number: 9200273
    Abstract: Protein scaffolds and scaffold libraries based on a fibronectin type III (FN3) repeat with an alternative binding surface design, isolated nucleic acids encoding the protein scaffolds, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: December 1, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Michael Diem, Steven Jacobs
  • Publication number: 20150337579
    Abstract: A hinge assembly is disclosed herein. An example includes a first knuckle including a first wall that defines a first cavity and second knuckle including a second wall that defines a second cavity. The example also includes a friction element disposed in both the first cavity defined by the first wall of the first knuckle and the second cavity defined by the second wall of the second knuckle to both rotatably and resistively couple the first knuckle to the second knuckle by application of a force directed toward the first wall and the second wall, the friction element including a third wall that defines a third cavity. Modifications and additions to, as well as other examples of, the hinge assembly are also disclosed herein.
    Type: Application
    Filed: December 17, 2012
    Publication date: November 26, 2015
    Inventor: Steven Jacobs
  • Patent number: 9156887
    Abstract: Non-natural albumin binding domains, polynucleotides encoding thereof and methods of making and using these domains and polynucleotides are useful in controlling the half-life of therapeutic molecules for patients.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: October 13, 2015
    Assignee: Janssen Biotech, Inc.
    Inventor: Steven Jacobs
  • Publication number: 20150286391
    Abstract: A method for smartwatch control, including: displaying content from a first content stream at face of the smartwatch, the face including a touchscreen coaxially arranged with a display; tracking a user gesture at the touchscreen; in response to user gesture categorization as a radially inward gesture, setting a second content stream as active, wherein the second content stream is different from the first content stream; and in response to user gesture categorization as a radially outward gesture, determining a direction of the user gesture, in response to the direction being a first direction, performing a positive action on the displayed content and in response to the direction being a second direction opposing the first, performing a negative action on the displayed content.
    Type: Application
    Filed: March 11, 2015
    Publication date: October 8, 2015
    Inventors: Steven Jacobs, Bruce Trip Vest, Kyle Dell'Aquila, Evan Wilson, AJ Cooper, Michael Miller, Michael Smith
  • Publication number: 20150102879
    Abstract: A magnetic coupling system for electromagnetically connecting an electric device to a mounting system, including: a first interface comprising a first plurality of magnetic elements and a first induction coil defining a first central axis, the first interface connected to the electric device; and a second interface comprising a second plurality of magnetic elements and a second induction coil defining a second central axis, the second interface connected to the mounting system, wherein magnetic attraction between the first and second plurality of magnetic elements biases the first interface toward the second interface and transiently retains the first and second induction coils in a substantially coaxial relationship.
    Type: Application
    Filed: October 13, 2014
    Publication date: April 16, 2015
    Inventors: Steven Jacobs, John McCarthy, Evan Wilson, Bruce Vest
  • Publication number: 20150104808
    Abstract: Cysteine engineered monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules comprising one or more free cysteine amino acids are prepared by mutagenizing a nucleic acid sequence of a parent molecule and replacing one or more amino acid residues by cysteine to encode the cysteine engineered FN3 domain containing monospecific or bispecific molecules; expressing the cysteine engineered FN3 domain containing molecules; and recovering the cysteine engineered FN3 domain containing molecule. Isolated cysteine engineered monospecific or bispecific FN3 domain containing molecules may be covalently attached to a detection label or a drug moiety and used therapeutically.
    Type: Application
    Filed: October 13, 2014
    Publication date: April 16, 2015
    Inventors: Shalom Goldberg, Steven Jacobs, Tricia Lin
  • Publication number: 20140313665
    Abstract: A first housing with a polar magnet on a first side. The first housing can include an opening on the first side. A second housing can include a sliding latch. An opposite polar magnet attached to the sliding latch. The polar magnet attracts the opposite polar magnet on the sliding latch to move the sliding latch to a latched position.
    Type: Application
    Filed: December 5, 2011
    Publication date: October 23, 2014
    Inventors: Michael Delpier, Stacy L. Wolff, Kevin L. Massaro, Daniel Koelker, Steven Jacobs, Dimitre Mehandjiysky
  • Publication number: 20140206599
    Abstract: IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.
    Type: Application
    Filed: March 26, 2014
    Publication date: July 24, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Michael Baumann, Gaby Tresch, Steven Jacobs, Karyn O'Neil
  • Patent number: 8761561
    Abstract: In general, in one aspect, the disclosure features a system that includes a flexible waveguide having a hollow core extending along a waveguide axis and a region surrounding the core, the region being configured to guide radiation from the CO2 laser along the waveguide axis from an input end to an output end of the waveguide. The system also includes a handpiece attached to the waveguide, wherein the handpiece allows an operator to control the orientation of the output end to direct the radiation to a target location of a patient and the handpiece includes a tip extending past the output end that provides a minimum standoff distance between the output end and the target location.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: June 24, 2014
    Assignee: OmniGuide, Inc.
    Inventors: Burak Temelkuran, Charalambos Anastassiou, David Torres, Gil Shapira, Max Shurgalin, Gregor Dellemann, Ori Weisberg, Steven A. Jacobs, Tairan Wang, Uri Kolodny, Jesse Rusk, Robert Payne, Yoel Fink
  • Publication number: 20140155325
    Abstract: Monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
    Type: Application
    Filed: November 20, 2013
    Publication date: June 5, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Anderson Mark, Ricardo Attar, Michael Diem, Linus Hyun, Steven Jacobs, Alastair King, Donna Klein, Sheri Moores, Karyn O'Neil, Kristen Picha
  • Publication number: 20140155326
    Abstract: Monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
    Type: Application
    Filed: November 21, 2013
    Publication date: June 5, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Anderson Mark, Ricardo Attar, Michael Diem, Linus Hyun, Steven Jacobs, Alastair King, Donna Klein, Sheri Moores, Karyn O'Neil, Kristen Picha
  • Patent number: D760614
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: July 5, 2016
    Assignee: Olio Devices, Inc.
    Inventors: Steven Jacobs, Trip Vest, Kyle Dell'Aquila, Evan Wilson, AJ Cooper, Michael Miller, Michael Smith