Abstract: Systems and methods for managing third party data are provided. A third party data management system includes a processing circuit. The processing circuit is configured to receive first third party activity data from a source computing system and via a cybersecurity correlation and analytics computing system, determine a computing entity external to the third party data management system associated with the third party activity data based on at least one item extracted from the first third party activity data, periodically monitor third party activity associated with the computing entity, comprising operations to collect second third party activity data, and correlate the monitored second third party activity data to an entity profile.

Abstract: Provided herein are, inter alia, methods and composition for the treatment of cancers that are recalcitrant to treatment and/or become resistant to certain drug treatments. The methods provided may, inter alia, be used to treat cancer in subjects having elevated STAT1 activity levels.

Abstract: A system for administering a status check to a medical device. The system includes a medical device unit comprising a control system, a writing device, and one or more components, the control system configured to transmit to the one or more components a request for status data regarding a status of the one or more components, receive status data from the one or more components, and write, using the writing device, the status data to a transmitting device, the transmitting device configured to store and transmit the status data.

Abstract: A system for administering a status check to a medical device. The system includes a medical device unit comprising a control system, a writing device, and one or more components, the control system configured to transmit to the one or more components a request for status data regarding a status of the one or more components, receive status data from the one or more components, and write, using the writing device, the status data to a transmitting device, the transmitting device configured to store and transmit the status data.

Abstract: A system for administering a status check to a medical device. The system includes a medical device unit comprising a control system, a writing device, and one or more components, the control system configured to transmit to the one or more components a request for status data regarding a status of the one or more components, receive status data from the one or more components, and write, using the writing device, the status data to a transmitting device, the transmitting device configured to store and transmit the status data.

Abstract: A system for administering a status check to a medical device. The system includes a medical device unit comprising a control system, a writing device, and one or more components, the control system configured to transmit to the one or more components a request for status data regarding a status of the one or more components, receive status data from the one or more components, and write, using the writing device, the status data to a transmitting device, the transmitting device configured to store and transmit the status data.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: A device for removable attachment to a bone of a living patient, useful as a mounting support for a trackable part of a computerized surgical navigation system and a method for attaching an object removably to a bone of a living patient. A shaft having a self drilling, self-tapping screw tip can be inserted transversely of the bone and securely screwed into the cortex. A screw drives a sharp-edged sleeve along the shaft to engage the near cortex. A stepping mechanism allows incremental angular movement of a portion of an adjustment mechanism and indicates when the sleeve is securely engaged by resisting further tightening.

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

Abstract: The pedicle screw extension system may include a removable cannulated extension provided to a pedicle screw tulip head. The cannulated extension may permit percutaneous implantation of pedicle screws followed by rod placement that may be guided by slots running along the length of the extension. The cannulation may allow for passage and attachment of secondary instruments, such as for example: a screw driving device, a rod measuring device, and a set screw driving device. The screw extension may also include secondary device attachment features allowing the rod to be pushed down in a screw tulip head and for extension removal as needed.

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

Abstract: Methods and apparatus are provided for allowing an operating system to automatically configure and operate multiple types of the same component. According to various embodiments, characteristic information associated with a particular component, such as a tuner, can be written to a nonvolatile memory. An operating system can be configured to read characteristic information from the nonvolatile memory associated with the component. In one example, the characteristic information includes power characteristics associated with the component. By providing characteristic information in a nonvolatile memory, a single version of an operating system can configure and operate many different versions and types of the same component.