Patents by Inventor Steven A. Jones

Steven A. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Antibody and antibody fragments for inhibiting the growth of tumors

Publication number: 20070116707

Abstract: Chimerized and humanized versions of anti EGF receptor antibody 225 and fragments thereof for treatment of tumors.

Type: Application

Filed: June 13, 2006

Publication date: May 24, 2007

Inventors: Neil Goldstein, Nicholas Giorgio, Steven Jones, Jose Saldanha
Blind rivet method

Publication number: 20070110540

Abstract: There is provided a blind rivet comprising an axially extending hollow tubular body having a tail end face at one end and a pre-formed radially enlarged flange at the other end, together with a mandrel having a stem which extends co-axially though the body and having enlarged head adjacent the tail end of the body, the stem having a weakened region immediately adjacent the head, whereby the mandrel head having an outer diameter greater than an outer diameter of said body, usually by between 4% and 9%, and which has a uniform conical shoulder extending between said outer diameter of the head and the stem, so as to exert a setting force having an axial component for compressing the rivet body axially and an angular component effecting conical deformation of the tail end radially.

Type: Application

Filed: January 12, 2007

Publication date: May 17, 2007

Inventors: Steven Jones, Stephen Morris, James Hughes
Method, apparatus and computer program product for implementing scan-chain-specific control signals as part of a scan chain

Publication number: 20070101221

Abstract: A method, apparatus and computer program product are provided for implementing scan-chain-specific control signals as an integral part of a scan chain. A scan input vector including scan data input and a scan control signal is applied to a register latch that forms the scan chain. The register latch includes a logic gate for combining a global clock control (THOLD) signal and the scan control signal. The scan control signal is routed around the register latch and including in a scan output vector including scan data output. Chain-specific control signals are eliminated from a clock control signal distribution tree used with the scan chain of the invention.

Type: Application

Filed: November 3, 2005

Publication date: May 3, 2007

Applicant: International Business Machines Corporation

Inventors: Mark Fredrickson, Scott Frei, Steven Jones
Use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases

Publication number: 20070093438

Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in spindle formation or microtubule function during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.

Type: Application

Filed: September 15, 2004

Publication date: April 26, 2007

Applicant: Cenix BioScience GMbH

Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski
Compositions comprising and methods of using norfluoxetine

Publication number: 20070078188

Abstract: The invention encompasses methods of using racemic and enantiomerically pure norfluoxetine, as well as pharmaceutical compositions, pharmaceutical unit dosage forms, and kits comprising racemic and enantiomerically pure norfluoxetine. In particular, the invention encompasses a method of inhibiting or reducing the production of PGE2. The invention further encompasses a method of treating or preventing inflammation in a patient, as well as a method of treating or preventing a disease or disorder such as, but not limited to, autoimmune diseases, arthritis, neurologic diseases, inflammatory diseases, fibromyalgia, pain resulting from inflammation, neuropathic pain, and cancer.

Type: Application

Filed: April 20, 2006

Publication date: April 5, 2007

Inventors: Mark Currie, Steven Jones, Chrisantha Senanayake, Zhi-Hiu Lu
Fatty acid modified forms of glucocorticoids

Publication number: 20070060555

Abstract: Compounds are disclosed of the formula in which R3 is C8 to C24 hydrocarbon or the residue of misoprostol. The compounds are useful for treating rhinitis and asthma, particularly by inhalation, and for treating inflammation, particularly by local or topical administration.

Type: Application

Filed: November 14, 2006

Publication date: March 15, 2007

Applicant: Sepracor Inc.

Inventors: Mark Currie, Steven Jones, Charles Zepp
Blind rivet and method

Publication number: 20070059120

Abstract: A blind rivet includes a hollow rivet body having a longitudinally extending indented groove. The groove may be shaped to impart rivet setting characteristics that may be varied to provide desirable fastening characteristics for joints in a number of industries. The shape of the indentation on the rivet body may be varied to cause a portion of the rivet body to collapse and form a secondary head at a predetermined longitudinal location.

Type: Application

Filed: September 15, 2005

Publication date: March 15, 2007

Inventors: Daniel Vigliotti, Edward McCusker, Jerry Robertson, Steven Jones, Daniel Smith
Carbon coated high luster materials

Patent number: 7189454

Abstract: A platy pigment substrate having a carbon-containing coating thereon is provided wherein the coating comprises a pyrolyzed carbon-containing ionic species. The products of the present invention may be used in any application where pearlescent pigments have been used heretofore including but not limited to automotive and industrial paint applications.

Type: Grant

Filed: May 7, 2004

Date of Patent: March 13, 2007

Assignee: Engelhard Corporation

Inventors: Geoffrey M. Johnson, Steven A. Jones, Ahmad Moini, Gerald S. Koermer, William M. Jaglowski
Low visibility laser marking additive

Patent number: 7187396

Abstract: Laser marking of plastic material is achieved by incorporating into the plastic a laser marking particulate additive having a particle size of less than 100 nm. A mixed oxide particle of tin and antimony having a particle size of 10–70 nm is useful as a laser marking additive when using a YAG laser. A metallic powder can further be added to improve marking contrast.

Type: Grant

Filed: November 1, 2004

Date of Patent: March 6, 2007

Assignee: Engelhard Corporation

Inventors: James B. Carroll, Jr., Steven A. Jones
Use of eukaryotic genes affecting chromatin separation for diagnosis and treatment of proliferative diseases

Publication number: 20070042981

Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in chromatin separation during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.

Type: Application

Filed: September 15, 2004

Publication date: February 22, 2007

Applicant: Cenix BioScience GmbH

Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski
Carbon coated high luster materials

Publication number: 20070026229

Abstract: A platy pigment substrate having a carbon-containing coating thereon is provided wherein the coating comprises a pyrolyzed carbon-containing ionic species. The products of the present invention may be used in any application where pearlescent pigments have been used heretofore including but not limited to automotive and industrial paint applications.

Type: Application

Filed: October 4, 2006

Publication date: February 1, 2007

Inventors: Geoffrey Johnson, Steven Jones, Ahmad Moini, Gerald Koermer, William Jaglowski
Use of eukaryotic genes affecting cell cycle control or cell cycle progression for diagnosis and treatment of proliferative diseases

Publication number: 20070015161

Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in cell cycle progression during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.

Type: Application

Filed: September 15, 2004

Publication date: January 18, 2007

Applicant: Cenix BioScience GmbH

Inventors: Christophe Echeverri, Anthony Hynan, Pierry Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski
Dual hybrid propulsion system

Publication number: 20070012493

Abstract: With the growing demand of oil products in the world, this invention can help curb the fuel consumption rate of trucks/large motor vehicles without reducing peak power outputs. A vehicle having a “dual series” hybrid power systems includes two liquid fueled internal combustion engines, each engine having a generator directly connected. There is an electric motor for drivability directly connected to one or more ground engaging wheels. A first electrical storage device (battery pack) stores electricity that powers the electric motor. Two voltage reducers are coupled between both of the generators and the first electrical storage device and has an accessory voltage output, which has a lower voltage than the charging power output of the generators, to keep the accessory second electrical storage device fully charged.

Type: Application

Filed: June 19, 2006

Publication date: January 18, 2007

Inventor: Steven Jones
Blind rivet, removal system and related method

Publication number: 20070003389

Abstract: The invention relates to a blind rivet, related method of removal and a tool. The removable blind rivet has a rivet body that receives a mandrel. The rivet body has a flange with a line of weakness formed therein. The line of weakness is adapted to shear under an axial load, whereby the flange is severed, substantially as a single item, from the rivet body. The invention extends to a tool for removing the rivet, the tool having: a body and a punch surface, the punch surface adapted to apply an axial force to a region of the flange, whereby the flange is severed from the rivet body in the form of an annulus, leaving a hollow rivet body that may be removed from a workpiece. The advantage of the invention is that it enables the flange to be removed form the rivet body as a single item.

Type: Application

Filed: June 12, 2006

Publication date: January 4, 2007

Inventors: Steven Jones, John Davies
Carbon coated high luster materials

Publication number: 20060292371

Abstract: A platy pigment substrate having a carbon-containing coating thereon is provided wherein the coating comprises a pyrolyzed carbon-containing ionic species. The products of the present invention may be used in any application where pearlescent pigments have been used heretofore including but not limited to automotive and industrial paint applications.

Type: Application

Filed: April 25, 2006

Publication date: December 28, 2006

Applicant: ENGELHARD CORPORATION

Inventors: Geoffrey Johnson, Steven Jones, Ahmad Moini, Gerald Koermer, William Jaglowski
Use of CR1-binding molecules in clearance and induction of immune responses

Publication number: 20060263792

Abstract: The present invention provides methods and compositions related to the discovery of molecules capable of both inducing an immune response to an antigen in a mammal and also effecting clearance of the antigen, with such molecules comprising a first moiety comprising an antigen binding portion which binds specifically to complement receptor 1 (CR1) and does not substantially bind to complement receptor 2 (CR2), linked to a second moiety which comprises the antigen or binds to the antigen. Methods of producing such molecules and their therapeutic and/or prophylactic uses are also featured.

Type: Application

Filed: October 31, 2005

Publication date: November 23, 2006

Applicant: EluSys Therapeutics, Inc.

Inventors: Nehal Mohamed, George Spitalny, Leslie Casey, Steven Jones, Steven Pincus
Honing guide assembly

Publication number: 20060211348

Abstract: A honing guide and bevel setting jig for removable attachment to the honing guide to properly position the angle and projection of a tool to be sharpened in the jig to enable the tool to be honed at the proper angle and position. An adjustable roller that contacts an abrasive surface during use of the guide facilitates formation of micro bevels. A tool securing bar having a generally triangular shape in the bar's middle section forces the arris-defining back of the tool being honed against a reference surface in the guide by tightening thumb nuts around threaded studs projecting from the bar. Jigs for use with both square and skew edge chisel and blades are described. A concave surface clamp bar honing guide provides enhanced gripping of the tool being honed, and wedges and adjustable structures expand the range of bevel angles that can be honed.

Type: Application

Filed: April 16, 2004

Publication date: September 21, 2006

Inventors: Brent Hyde, Steven Jones, Robin Lee, Scott Roger, Terry Saunders, Matthew Siemers
Recombinant vesicular stomatitis virus vaccines for viral hemorrhagic fevers

Publication number: 20060193872

Abstract: Recombinant VSV viral particles and the use thereof as vaccines for immunization are described.

Type: Application

Filed: July 28, 2003

Publication date: August 31, 2006

Inventors: Steven Jones, Heinz Feldman, Ute Stroeher
Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the NHE-inhibitory efficacy of compounds

Publication number: 20060183928

Abstract: Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.

Type: Application

Filed: April 15, 2004

Publication date: August 17, 2006

Inventors: Michael Zasloff, Ann Shinnar, William Kinney, Steven Jones
Treatment of neovascularization disorders with squalamine

Publication number: 20060166950

Abstract: Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.

Type: Application

Filed: March 16, 2006

Publication date: July 27, 2006

Inventors: Michael Zasloff, Ann Shinnar, William Kinney, Steven Jones

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