Patents by Inventor Steven A. N. Goldstein

Steven A. N. Goldstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of reducing neuronal electrical activity with a potassium channel subunit
    Patent number: 7192773
    Abstract: Methods of reducing the excitability of an excitable cell by transforming an excitable cell with a nucleic acid construct encoding an open rectifier K+ channel (dORK) (SEQ ID NO:2) or a modified open rectifier K+ channel (dORK?) (SEQ ID NO:4), and expressing the open rectifier K+ channel in the excitable cell, wherein the excitability of the transformed cell is reduced. Also featured are transgenic animals expressing dORK or dORK?.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: March 20, 2007
    Assignee: New York University
    Inventors: Michael N. Nitabach, Justin Blau, Todd C. Holmes, Steven A. N. Goldstein
  • Polymorphisms associated with cardiac arrythmia
    Publication number: 20040086886
    Abstract: The invention relates generally to the discovery of specific nucleotide polymorphisms in the KCNE2 gene and the association of these polymorphisms with antibiotic-induced LQTS. Related composition screening systems and diagnostic and prognostic assays are provided.
    Type: Application
    Filed: July 23, 2003
    Publication date: May 6, 2004
    Inventor: Steven A.N. Goldstein
  • Method of reducing neuronal electrical activity with a potassium channel subunit
    Publication number: 20030237102
    Abstract: Methods of reducing the excitability of an excitable cell by transforming an excitable cell with a nucleic acid construct encoding an open rectifier K+ channel (dORK) (SEQ ID NO:2) or a modified open rectifier K+ channel (dORK&Dgr;) (SEQ ID NO:4), and expressing the open rectifier K+ channel in the excitable cell, wherein the excitability of the transformed cell is reduced. Also featured are transgenic animals expressing dORK or dORK&Dgr;.
    Type: Application
    Filed: May 15, 2003
    Publication date: December 25, 2003
    Inventors: Michael N. Nitabach, Justin Blau, Todd C. Holmes, Steven A. N. Goldstein