Patents by Inventor Steven A. ROSENZWEIG

Steven A. ROSENZWEIG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE NANOTUBES LINKED BY DISULFIDE BONDS FOR TARGETED DELIVERY OF CYTOTOXIC THERAPIES
    Publication number: 20200206313
    Abstract: Provided herein is a self-assembling polypeptide-based nanotube system having the ability to target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help of multiple RGD units present along their surface and release their drug payload in a sustained manner. In addition, the nanotubes can be utilized for cellular imaging using any covalently tagged fluorescent dye. Provided herein is a self-assembling polypeptide-based nanotube system having the ability to target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help of multiple RGD units present along their surface and release their drug payload in a sustained manner. In addition, the nanotubes can be utilized for cellular imaging using any covalently tagged fluorescent dye.
    Type: Application
    Filed: December 23, 2019
    Publication date: July 2, 2020
    Applicants: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT, INDIAN INSTITUTE OF SCIENCE
    Inventors: Steven A. ROSENZWEIG, Hanudatta S. ATREYA, Asampilli GITANJALI, Paturu KONDAIAH