Patents by Inventor Steven A. Scampini
Steven A. Scampini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10271826Abstract: A swab assembly for collecting a specimen from a patient includes an elongated shaft having a proximal end, a distal end, and a notch between its proximal and distal ends; a sheath having a proximal end, a distal end, and a lumen extending between its proximal and distal ends, wherein a portion of the elongated shaft is disposed within the sheath lumen, and the sheath is slidable relative to the elongated shaft; and a collection tip coupled to the distal end of the elongated shaft and configured for obtaining the specimen. The sheath is slidable between a first position in which the shaft notch is disposed within the sheath lumen and wherein the sheath protects the elongated shaft from breaking at the notch, and a second position in which the shaft notch is exposed out of the sheath lumen.Type: GrantFiled: January 10, 2013Date of Patent: April 30, 2019Assignee: HOLOGIC, INC.Inventors: Steven A. Scampini, Ryan P. Oliva
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Publication number: 20140255940Abstract: A biological sample well plate includes a plate member having a top surface and a plurality of wells therein, each well being defined by an opening in the plate member top surface and an inner well surface that slopes downwardly to a well bottom having an upwardly extending projection, such that each well bottom of the plurality of wells defines a circumferential trough.Type: ApplicationFiled: March 7, 2013Publication date: September 11, 2014Applicant: HOLOGIC, INC.Inventors: Raymond A. Jenoski, Steven A. Scampini
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Publication number: 20140194777Abstract: A swab assembly for collecting a specimen from a patient includes an elongated shaft having a proximal end, a distal end, and a notch between its proximal and distal ends; a sheath having a proximal end, a distal end, and a lumen extending between its proximal and distal ends, wherein a portion of the elongated shaft is disposed within the sheath lumen, and the sheath is slidable relative to the elongated shaft; and a collection tip coupled to the distal end of the elongated shaft and configured for obtaining the specimen. The sheath is slidable between a first position in which the shaft notch is disposed within the sheath lumen and wherein the sheath protects the elongated shaft from breaking at the notch, and a second position in which the shaft notch is exposed out of the sheath lumen.Type: ApplicationFiled: January 10, 2013Publication date: July 10, 2014Applicant: HOLOGIC, INC.Inventors: Steven A. Scampini, Ryan P. Oliva
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Publication number: 20120112384Abstract: Methods and apparatus for bonding block of paraffin having cellular material embedded at one end thereof with an additional amount of paraffin are disclosed, including a method comprising placing the paraffin block in a well of a mold with the paraffin-embedded cellular material positioned on a support structure that elevates the cellular matter from a bottom surface of the well; heating the mold to thereby soften and at least partially melt and blend together the embedding paraffin and additional paraffin located in the well, the support structure sized such that some of the additional paraffin flows on the bottom surface of the well at least partially surrounding the support structure; and cooling the mold to thereby bond the additional paraffin to the embedding paraffin and re-solidify the paraffin block, wherein the retained cellular matter is spaced apart from an end of the re-solidified paraffin block defined by the bottom surface of the well.Type: ApplicationFiled: January 18, 2012Publication date: May 10, 2012Applicant: Cytyc CorporationInventors: Eric BAUR, Steven SCAMPINI
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Patent number: 8137642Abstract: A bubble point of a combination of a filter and a liquid is calibrated by applying an initial back pressure through the filter toward the liquid; taking a first plurality of measurements of the level of the liquid in the container; calculating a first variance of the first plurality of measurements; and comparing the first calculated variance with a known threshold variance. Then a second plurality of measurements of the level of the liquid in the container is taken; a second variance of the second plurality of measurements is calculated; and the second calculated variance is compared with a known threshold variance. The above described steps are repeated at incrementally increased back pressures until the first and second calculated variances are each greater than or equal to the known threshold variance, which is about 0.01. The bubble point is determined to be the back pressure at that point. If the determined bubble point is less than or equal to the known threshold bubble point, which is about 0.Type: GrantFiled: June 11, 2009Date of Patent: March 20, 2012Assignee: Cytyc CorporationInventors: Timothy Hutchins, Steven Scampini, Eric Baur
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Patent number: 8137958Abstract: A system for collecting a biological sample includes a collection device comprising a cylindrical body having a bore extending there through and a filter membrane disposed at one end thereof; a filter plug having an insert configured for insertion into the bore; a collar concentrically mounted about the exterior surface of the insert and configured for insertion into the bore; and a gasket disposed about the exterior surface of the insert, wherein an outer dimension of the gasket is variable in response to relative movement between the collar and the insert, and wherein the gasket has a cross section with two end portions and a mid portion that is located radially further away from the insert than the two end portions.Type: GrantFiled: December 19, 2008Date of Patent: March 20, 2012Assignee: Cytyc CorporationInventors: Eric E. Grimes, Steven A. Scampini, Ryan Oliva, Tuan Ha
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Patent number: 8118962Abstract: Methods and apparatus for bonding block of paraffin having cellular material embedded at one end thereof with an additional amount of paraffin are disclosed, including a method comprising placing the paraffin block in a well of a mold with the paraffin-embedded cellular material positioned on a support structure that elevates the cellular matter from a bottom surface of the well; heating the mold to thereby soften and at least partially melt and blend together the embedding paraffin and additional paraffin located in the well, the support structure sized such that some of the additional paraffin flows on the bottom surface of the well at least partially surrounding the support structure; and cooling the mold to thereby bond the additional paraffin to the embedding paraffin and re-solidify the paraffin block, wherein the retained cellular matter is spaced apart from an end of the re-solidified paraffin block defined by the bottom surface of the well.Type: GrantFiled: November 10, 2008Date of Patent: February 21, 2012Assignee: CYTYC CorporationInventors: Eric Baur, Steven A. Scampini
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Patent number: 8088329Abstract: A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well.Type: GrantFiled: September 7, 2010Date of Patent: January 3, 2012Assignee: Cytyc CorporationInventors: Timothy Hutchins, Hal Watts, Steven A. Scampini, Eric Grimes, Andrew H. Fischer
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Patent number: 7914738Abstract: A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well.Type: GrantFiled: August 15, 2007Date of Patent: March 29, 2011Assignee: Cytyc CorporationInventors: Timothy Hutchins, Hal Watts, Steven A. Scampini, Eric Grimes
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Patent number: 7914462Abstract: A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well.Type: GrantFiled: August 15, 2007Date of Patent: March 29, 2011Assignee: Cytyc CorporationInventors: Timothy Hutchins, Hal Watts, Steven Scampini, Eric Grimes, Andrew H. Fischer
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Patent number: 7901946Abstract: A tissue cassette assembly includes a housing having a recess formed therein, and a compressible reservoir disposed partially or wholly inside of, or otherwise attached in fluid communication with, the housing recess, the compressible reservoir containing a tissue embedding material. The tissue cassette further includes a port disposed in the housing, the port in fluid communication with the compressible reservoir at one end and terminating in a sample cavity at another end. During operation, the compressible reservoir is compressed or squeezed to release the tissue embedding material into the sample cavity containing the biological sample.Type: GrantFiled: January 7, 2010Date of Patent: March 8, 2011Assignee: Cytyc CorporationInventor: Steven A. Scampini
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Publication number: 20100330660Abstract: A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well.Type: ApplicationFiled: September 7, 2010Publication date: December 30, 2010Applicant: CYTYC CORPORATIONInventors: Timothy Hutchins, Hal Watts, Steven A. Scampini, Eric Grimes, Andrew H. Fischer
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Patent number: 7859667Abstract: A system and method for determining whether one or more slides are loaded properly within a cassette. Each slide includes one or more transparent regions and one or more non-transparent regions. The slides are between a light source and a sensor. The light source generates light that is directed towards the sensor through the slides. If the sensor is able to detect light from the light source, then the slides are properly loaded in the cassette. Slides are not properly loaded if the light is blocked by a non-transparent region before reaching the sensor. The sensor or a separate controller can generate a signal or data to provide an indication to a user or to processing equipment that the slides are or are not properly loaded. For example, a speaker or an indicator light can be used to provide an indication to the user. The signal or data can also be used for other functions, such as displaying a message on a screen indicating whether the slides are properly loaded.Type: GrantFiled: November 1, 2007Date of Patent: December 28, 2010Assignee: Cytyc CorporationInventor: Steven A. Scampini
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Patent number: 7829021Abstract: A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well.Type: GrantFiled: August 15, 2007Date of Patent: November 9, 2010Assignee: CYTYC CorporationInventors: Timothy Hutchins, Hal Watts, Steven Scampini, Eric Grimes, Andrew H. Fischer
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Patent number: 7796789Abstract: A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. An interventional system (20) is used to operate the invasive medical device (30) and produces spatially-based information relating to the activity of the invasive medical device (30). The spatially-based information from the interventional system (20) is merged into the three dimensional ultrasonic image data to produce a live three dimensional image of the invasive medical device (30) or its activity. In one embodiment the locations where the activity of the invasive medical device (30) is performed is recorded and displayed in the three dimensional ultrasonic image. The three dimensional ultrasonic image may be shown as an anatomical volume rendered image or as a wire frame model (130) of the anatomy. In another embodiment an integrated three dimensional ultrasonic imaging and invasive device system is described.Type: GrantFiled: March 4, 2004Date of Patent: September 14, 2010Assignee: Koninklijke Philips Electronics N.V.Inventors: Ivan Salgo, Bernard Savord, Steven Scampini, Michael Peszynski
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Publication number: 20100112629Abstract: A tissue cassette assembly includes a housing having a recess formed therein, and a compressible reservoir disposed partially or wholly inside of, or otherwise attached in fluid communication with, the housing recess, the compressible reservoir containing a tissue embedding material. The tissue cassette further includes a port disposed in the housing, the port in fluid communication with the compressible reservoir at one end and terminating in a sample cavity at another end. During operation, the compressible reservoir is compressed or squeezed to release the tissue embedding material into the sample cavity containing the biological sample.Type: ApplicationFiled: January 7, 2010Publication date: May 6, 2010Applicant: CYTYC CORPORATIONInventor: Steven A. Scampini
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Patent number: 7666358Abstract: A tissue cassette assembly includes a housing having a recess formed therein, and a compressible reservoir disposed partially or wholly inside of, or otherwise attached in fluid communication with, the housing recess, the compressible reservoir containing a tissue embedding material. The tissue cassette further includes a port disposed in the housing, the port in fluid communication with the compressible reservoir at one end and terminating in a sample cavity at another end. During operation, the compressible reservoir is compressed or squeezed to release the tissue embedding material into the sample cavity containing the biological sample.Type: GrantFiled: October 20, 2006Date of Patent: February 23, 2010Assignee: Cytyc CorporationInventor: Steven A. Scampini
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Publication number: 20090312955Abstract: A bubble point of a combination of a filter and a liquid is calibrated by applying an initial back pressure through the filter toward the liquid; taking a first plurality of measurements of the level of the liquid in the container; calculating a first variance of the first plurality of measurements; and comparing the first calculated variance with a known threshold variance. Then a second plurality of measurements of the level of the liquid in the container is taken; a second variance of the second plurality of measurements is calculated; and the second calculated variance is compared with a known threshold variance. The above described steps are repeated at incrementally increased back pressures until the first and second calculated variances are each greater than or equal to the known threshold variance, which is about 0.01. The bubble point is determined to be the back pressure at that point. If the determined bubble point is less than or equal to the known threshold bubble point, which is about 0.Type: ApplicationFiled: June 11, 2009Publication date: December 17, 2009Applicant: CYTYC CORPORATIONInventors: Timothy Hutchins, Steven A. Scampini, Eric Baur
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Publication number: 20090165940Abstract: Methods and apparatus for bonding block of paraffin having cellular material embedded at one end thereof with an additional amount of paraffin are disclosed, including a method comprising placing the paraffin block in a well of a mold with the paraffin-embedded cellular material positioned on a support structure that elevates the cellular matter from a bottom surface of the well; heating the mold to thereby soften and at least partially melt and blend together the embedding paraffin and additional paraffin located in the well, the support structure sized such that some of the additional paraffin flows on the bottom surface of the well at least partially surrounding the support structure; and cooling the mold to thereby bond the additional paraffin to the embedding paraffin and re-solidify the paraffin block, wherein the retained cellular matter is spaced apart from an end of the re-solidified paraffin block defined by the bottom surface of the well.Type: ApplicationFiled: November 10, 2008Publication date: July 2, 2009Applicant: CYTYC CORPORATIONInventors: Eric Baur, Steven Scampini
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Publication number: 20090162930Abstract: A system for collecting a biological sample includes a collection device comprising a cylindrical body having a bore extending there through and a filter membrane disposed at one end thereof; a filter plug having an insert configured for insertion into the bore; a collar concentrically mounted about the exterior surface of the insert and configured for insertion into the bore; and a gasket disposed about the exterior surface of the insert, wherein an outer dimension of the gasket is variable in response to relative movement between the collar and the insert, and wherein the gasket has a cross section with two end portions and a mid portion that is located radially further away from the insert than the two end portions.Type: ApplicationFiled: December 19, 2008Publication date: June 25, 2009Applicant: CYTYC CORPORATIONInventors: Eric E. Grimes, Steven A. Scampini, Ryan Oliva, Tuan Ha