Patents by Inventor Steven A. Seelig

Steven A. Seelig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10351912
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: July 16, 2019
    Assignee: Abbott Molecular Inc.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Patent number: 9790558
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: October 17, 2017
    Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Patent number: 9534254
    Abstract: The method of the invention comprises the stratification of a cancer patient population into various cancer therapy groups based on analysis by genomic DNA microarray of multiple gene amplifications or deletions present or absent in the diseased tissue of each patient. In particular, the invention involves patient stratification into one of at least four cancer therapy groups based on the microarray analysis of gene amplification or gene deletion at multiple chromosome locations.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: January 3, 2017
    Assignee: Abbott Molecular Inc.
    Inventor: Steven A. Seelig
  • Publication number: 20150337391
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: June 1, 2015
    Publication date: November 26, 2015
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Patent number: 9045802
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: June 2, 2015
    Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20150072884
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: July 15, 2014
    Publication date: March 12, 2015
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Patent number: 8785129
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: July 22, 2014
    Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20130316344
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: May 13, 2013
    Publication date: November 28, 2013
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20120276540
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: July 2, 2012
    Publication date: November 1, 2012
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20120164626
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Application
    Filed: October 24, 2011
    Publication date: June 28, 2012
    Applicant: VYSIS, INC.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Publication number: 20120141987
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: July 14, 2011
    Publication date: June 7, 2012
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Patent number: 8043805
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: October 25, 2011
    Assignee: Vysis, Inc.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Patent number: 7998678
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: August 16, 2011
    Assignees: VYSIS, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Patent number: 7998670
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: August 16, 2011
    Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20110177510
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 21, 2011
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
  • Publication number: 20090298087
    Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.
    Type: Application
    Filed: August 6, 2009
    Publication date: December 3, 2009
    Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
  • Publication number: 20090269768
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Application
    Filed: April 13, 2009
    Publication date: October 29, 2009
    Applicant: Vysis, Inc.
    Inventors: IRINA A. SOKOLOVA, STEVEN A. SEELIG, LARRY E. MORRISON, WALTER KING, ALICIA ALGECIRAS-SCHIMNICH
  • Patent number: 7517645
    Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: April 14, 2009
    Assignee: VYSIS, Inc.
    Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
  • Publication number: 20080032302
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Application
    Filed: May 21, 2007
    Publication date: February 7, 2008
    Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, VYSIS, INC.
    Inventors: Kevin Halling, Robert Jenkins, Walter King, Irina Sokolova, Steven Seelig
  • Patent number: 7232655
    Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: June 19, 2007
    Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.
    Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig