Patents by Inventor Steven A. Seelig
Steven A. Seelig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10351912Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.Type: GrantFiled: October 24, 2011Date of Patent: July 16, 2019Assignee: Abbott Molecular Inc.Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
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Patent number: 9790558Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: GrantFiled: June 1, 2015Date of Patent: October 17, 2017Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Patent number: 9534254Abstract: The method of the invention comprises the stratification of a cancer patient population into various cancer therapy groups based on analysis by genomic DNA microarray of multiple gene amplifications or deletions present or absent in the diseased tissue of each patient. In particular, the invention involves patient stratification into one of at least four cancer therapy groups based on the microarray analysis of gene amplification or gene deletion at multiple chromosome locations.Type: GrantFiled: March 31, 2000Date of Patent: January 3, 2017Assignee: Abbott Molecular Inc.Inventor: Steven A. Seelig
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Publication number: 20150337391Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: June 1, 2015Publication date: November 26, 2015Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Patent number: 9045802Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: GrantFiled: July 15, 2014Date of Patent: June 2, 2015Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20150072884Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: July 15, 2014Publication date: March 12, 2015Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Patent number: 8785129Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: GrantFiled: May 13, 2013Date of Patent: July 22, 2014Assignees: Mayo Foundation for Medical Education and Research, Abbott Molecular Inc.Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20130316344Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: May 13, 2013Publication date: November 28, 2013Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20120276540Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: July 2, 2012Publication date: November 1, 2012Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20120164626Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.Type: ApplicationFiled: October 24, 2011Publication date: June 28, 2012Applicant: VYSIS, INC.Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
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Publication number: 20120141987Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.Type: ApplicationFiled: July 14, 2011Publication date: June 7, 2012Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
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Patent number: 8043805Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.Type: GrantFiled: April 13, 2009Date of Patent: October 25, 2011Assignee: Vysis, Inc.Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
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Patent number: 7998678Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.Type: GrantFiled: August 6, 2009Date of Patent: August 16, 2011Assignees: VYSIS, Inc., Mayo Foundation for Medical Education and ResearchInventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
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Patent number: 7998670Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: GrantFiled: May 21, 2007Date of Patent: August 16, 2011Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20110177510Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: March 31, 2011Publication date: July 21, 2011Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
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Publication number: 20090298087Abstract: Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are present the sample. Also included are methods of selecting a combination of probes for the detection of cancer.Type: ApplicationFiled: August 6, 2009Publication date: December 3, 2009Inventors: Larry E. Morrison, Irina A. Sokolova, Steven A. Seelig, Kevin C. Halling
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Publication number: 20090269768Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.Type: ApplicationFiled: April 13, 2009Publication date: October 29, 2009Applicant: Vysis, Inc.Inventors: IRINA A. SOKOLOVA, STEVEN A. SEELIG, LARRY E. MORRISON, WALTER KING, ALICIA ALGECIRAS-SCHIMNICH
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Patent number: 7517645Abstract: Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.Type: GrantFiled: June 2, 2004Date of Patent: April 14, 2009Assignee: VYSIS, Inc.Inventors: Irina A. Sokolova, Steven A. Seelig, Larry E. Morrison, Walter King, Alicia Algeciras-Schimnich
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Publication number: 20080032302Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: ApplicationFiled: May 21, 2007Publication date: February 7, 2008Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, VYSIS, INC.Inventors: Kevin Halling, Robert Jenkins, Walter King, Irina Sokolova, Steven Seelig
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Patent number: 7232655Abstract: Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.Type: GrantFiled: April 12, 2002Date of Patent: June 19, 2007Assignees: Mayo Foundation for Medical Education and Research, Vysis, Inc.Inventors: Kevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig