Patents by Inventor Steven A. Titus

Steven A. Titus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARYLTHIAZOLYL PIPERIDINES AND RELATED COMPOUNDS AS MODULATORS OF SURVIVAL MOTOR NEURON (SMN) PROTEIN PRODUCTION
    Publication number: 20130096160
    Abstract: Aryl substituted thiazol-2-yl-piperidines and related compounds useful as modulators of survival motor neuron (SMN) protein production are provided herein. Without being bound to any particular theory it is believed the aryl substituted thiazol-2-yl-piperidines and related compounds provided herein act to increase production of the SMN2 form of survival motor neuron protein. These compounds are useful for treating spinal muscular atrophy. Pharmaceutical compositions containing a carrier and one or more of the aryl substituted thiazol-2-yl-piperidine or related compounds described herein are also provided. Methods of treating spinal muscular atrophy are also provided by this disclosure.
    Type: Application
    Filed: April 14, 2011
    Publication date: April 18, 2013
    Applicants: Secretary, Department of Health and Human Services
    Inventors: Juan Jose Marugan, Jingbo Xiao, Steven A. Titus, Noel Southall, Wei Zheng, Elliot J. Androphy, Jonathan Cherry
  • Potassium ion channel genes and proteins
    Patent number: 6087488
    Abstract: Novel genes in the erg subfamily of potassium channel proteins in humans are described. This family of proteins, and the genes encoding the proteins, are implicated in the development of long Q-T syndrome, a rare, but often fatal, cardiac arrhythmia.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: July 11, 2000
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Barry S. Ganetzky, Steven A. Titus
  • Polynucleotides encoding herg-3
    Patent number: 5986081
    Abstract: Novel genes in the erg subfamily of potassium channel proteins in humans are described. This family of proteins, and the genes encoding the proteins, are implicated in the development of long Q-T syndrome rare, but often fatal, cardiac arrhythmia.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: November 16, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Barry S. Ganetzky, Steven A. Titus