Abstract: Described herein are polymers prepared from multifunctional monomers, according to a defined sequential reaction scheme in a one-pot system, along with methods of making the same. Also described herein are tunable, 3D printed materials prepared from resin mixtures described herein. The 3D printed materials possess a large range of material properties, including tunable elastic moduli properties.

Abstract: The present disclosure features non-canonical or heavy isotope-containing amino acids, where the alpha-amino terminus and/or carboxylic acid terminus is modified with molecular cages. The molecular cage-modified amino acids are precluded from metabolic incorporation into proteins within living bacterial, plant, or mammalian cells, or from cell-free protein expression. Once uncaged, the amino acids are readily recognized by native and/or engineered tRNA synthetases, and can subsequently be incorporated into newly-synthesized proteins during protein translation.