Patents by Inventor Steven B. Jung
Steven B. Jung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9456890Abstract: A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.Type: GrantFiled: January 14, 2013Date of Patent: October 4, 2016Assignee: The Curators of the University of MissouriInventors: Delbert E. Day, Steven B. Jung
-
Patent number: 9402724Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.Type: GrantFiled: December 20, 2012Date of Patent: August 2, 2016Assignee: MO-SCI CORPORATIONInventors: Thomas E. Day, Steven B. Jung, Charanpreet S. Bagga
-
Publication number: 20160008133Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.Type: ApplicationFiled: December 20, 2012Publication date: January 14, 2016Inventors: Thomas E. Day, Erik M. Erbe, Steven B. Jung
-
Patent number: 8821919Abstract: A method for debridement of wound on the skin by placing against the wound a glass-based borate-based composition to release dissolution products which support neutrophilic activity into the wound by dissolution.Type: GrantFiled: May 18, 2012Date of Patent: September 2, 2014Assignees: Mo/Sci Corporation, The Curators of the University of MissouriInventor: Steven B. Jung
-
Publication number: 20140214173Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.Type: ApplicationFiled: March 27, 2014Publication date: July 31, 2014Inventors: Thomas E. Day, Erik M. Erbe, Steven B. Jung
-
Publication number: 20140180434Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.Type: ApplicationFiled: December 20, 2012Publication date: June 26, 2014Inventors: Thomas E. Day, Erik M. Erbe, Steven B. Jung
-
Publication number: 20140037756Abstract: A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B2O3, and two or more other oxides, wherein the scaffold body has a porosity between about 15 and about 90 vol %.Type: ApplicationFiled: July 8, 2013Publication date: February 6, 2014Applicant: The Curators of the University of MissouriInventors: Delbert E. Day, Steven B. Jung, Roger F. Brown
-
Publication number: 20140017320Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.Type: ApplicationFiled: September 16, 2013Publication date: January 16, 2014Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
-
Publication number: 20130309274Abstract: A method for debridement of wound on the skin by placing against the wound a glass-based borate-based composition to release dissolution products which support neutrophilic activity into the wound by dissolution.Type: ApplicationFiled: May 18, 2012Publication date: November 21, 2013Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventor: Steven B. Jung
-
Patent number: 8551513Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Si, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.Type: GrantFiled: October 1, 2012Date of Patent: October 8, 2013Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
-
Patent number: 8535710Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.Type: GrantFiled: April 9, 2012Date of Patent: September 17, 2013Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
-
Patent number: 8481066Abstract: A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B2O3, and two or more other oxides, wherein the scaffold body has a porosity between about 15 and about 90 vol %.Type: GrantFiled: July 16, 2009Date of Patent: July 9, 2013Assignee: The Curators of the University of MissouriInventors: Delbert E. Day, Steven B. Jung, Roger F. Brown
-
Patent number: 8353966Abstract: A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.Type: GrantFiled: January 15, 2009Date of Patent: January 15, 2013Assignee: The Curators of the University of MissouriInventors: Delbert E. Day, Steven B. Jung
-
Patent number: 8337875Abstract: A method for directing vessel growth toward a blood-deficient site in a mammal comprising implanting into the mammal an assembly of at glass fibers to form a vascular bridge with a first end of the vascular bridge in contact with the blood-deficient site and a second end of the vascular bridge remote from the blood-deficient site. Over time the bridge biodegrades and promotes vascularity in the direction of the bridge.Type: GrantFiled: January 6, 2010Date of Patent: December 25, 2012Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
-
Publication number: 20120276218Abstract: A biocompatible composition for tissue repair or regeneration in mammals comprising one or more glass former compounds selected from the group consisting of B2O3, P2O5, and SiO2 and director elements selected from the group consisting of Cu, Sr, Zn, Fe, Mn, Cr, V, Nb, Mo, W, Ba, Co, S, Al, Ti, Y, Mg, Si and/or Ni to promote in vivo calcium compound formation of calcium carbonate or other calcium compounds other than hydroxyapatite. Upon direct application of the biocompatible composition to a mammalian host, calcium carbonate or other calcium compounds other than hydroxyapatite form upon bioreaction of the composition with bodily fluids.Type: ApplicationFiled: July 6, 2012Publication date: November 1, 2012Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
-
Patent number: 8287896Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.Type: GrantFiled: January 6, 2010Date of Patent: October 16, 2012Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
-
Publication number: 20120220911Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.Type: ApplicationFiled: April 9, 2012Publication date: August 30, 2012Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
-
Patent number: 8173154Abstract: A method and compositions for wound care management comprising a dressing comprising a three-dimensional body of glass-based fibers comprising 40 to 80 weight % B2O3, wherein at least 25 wt. % of the fibers have a diameter between 200 nm and 4000 nm, and a length:width aspect ratio of at least 10. The glasses may also be used for wound care as fibers formed into sutures, as particles in surgical glue to close a wound, or as particles in an ointment or cream to apply to a wound. The compositions may comprise glass formers P2O5 and/or SiO2; alkali oxides selected from Li2O, Na2O, K2O, and Rb2O; and/or alkaline earth oxides selected from MgO, SrO, BaO and CaO. The compositions may further comprise 0.05 to 10 wt. % of one or more trace elements selected from Ag, Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn.Type: GrantFiled: January 6, 2010Date of Patent: May 8, 2012Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
-
Publication number: 20110165217Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.Type: ApplicationFiled: January 6, 2010Publication date: July 7, 2011Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
-
Publication number: 20110165221Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.Type: ApplicationFiled: January 6, 2010Publication date: July 7, 2011Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day