Patents by Inventor Steven B. Silbering

Steven B. Silbering has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7256216
    Abstract: A liquid pharmaceutical composition of a GABA analog comprising at least one polyhydric alcohol containing 2 to 6 carbon atoms having a pH of about 5.5 to about 7.0 and additionally a two-component liquid pharmaceutical composition comprising a first component comprising a powder mixture comprising a GABA analog and a solid polyhydric alcohol, and a second component comprising a liquid base are described, as well as methods to prepare the compositions and a method for treating cerebral diseases, including epilepsy, faintness attacks, hypokinesia and cranial traumas, neurodegenerative disorders, depression, mania and bipolar disorders, anxiety, panic, inflammation, renal colic, insomnia, gastrointestinal damage, incontinence, pain, including neuropathic pain, muscular pain, skeletal pain, and migraine using a therapeutically effective amount of the pharmaceutical compositions.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: August 14, 2007
    Inventors: Neema M. Kulkarni, Michael Schneider, Steven B. Silbering, Hans Meyer-Wonnay, Nahid Sanii-Yahyai
  • Publication number: 20040072904
    Abstract: A liquid pharmaceutical composition of a GABA analog comprising at least one polyhydric alcohol containing 2 to 6 carbon atoms having a pH of about 5.5 to about 7.0 and additionally a two-component liquid pharmaceutical composition comprising a first component comprising a powder mixture comprising a GABA analog and a solid polyhydric alcohol, and a second component comprising a liquid base are described, as well as methods to prepare the compositions and a method for treating cerebral diseases, including epilepsy, faintness attacks, hypokinesia and cranial traumas, neurodegenerative disorders, depression, mania and bipolar disorders, anxiety, panic, inflammation, renal colic, insomnia, gastrointestinal damage, incontinence, pain, including neuropathic pain, muscular pain, skeletal pain, and migraine using a therapeutically effective amount of the pharmaceutical compositions.
    Type: Application
    Filed: June 24, 2003
    Publication date: April 15, 2004
    Inventors: Neema M. Kulkarni, Michael Schneider, Steven B. Silbering, Hans Meyer-Wonnay, Nahid Sanii-Yahyai
  • Publication number: 20020198261
    Abstract: A liquid pharmaceutical composition of a GABA analog comprising at least one polyhydric alcohol containing 2 to 6 carbon atoms having a pH of about 5.5 to about 7.0 and additionally a two-component liquid pharmaceutical composition comprising a first component comprising a powder mixture comprising a GABA analog and a solid polyhydric alcohol, and a second component comprising a liquid base are described, as well as methods to prepare the compositions and a method for treating cerebral diseases, including epilepsy, faintness attacks, hypokinesia and cranial traumas, neurodegenerative disorders, depression, mania and bipolar disorders, anxiety, panic, inflammation, renal colic, insomnia, gastrointestinal damage, incontinence, pain, including neuropathic pain, muscular pain, skeletal pain, and migraine using a therapeutically effective amount of the pharmaceutical compositions.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 26, 2002
    Inventors: Neema M. Kulkarni, Michael Schneider, Steven B. Silbering, Hans Meyer-Wonnay
  • Patent number: 4965203
    Abstract: Improved thrombin formulations, stable at room temperature using stabilizing quantities of a polyol and a buffer at specific pHs are described wherein crude thrombin is first purified by two-stage ion exchange chromatography.
    Type: Grant
    Filed: June 13, 1989
    Date of Patent: October 23, 1990
    Assignee: Warner-Lambert Company
    Inventors: Steven B. Silbering, Rowland P. Blythe, Jr., Russell U. Nesbitt, Jr., Mahdi B. Fawzi
  • Patent number: 4696812
    Abstract: Thrombin solutions can be rendered storage stable using stabilizing quantities of an anti-autolytic buffer in combination with low levels of saline and glycerol to prevent denaturation.
    Type: Grant
    Filed: October 28, 1985
    Date of Patent: September 29, 1987
    Assignee: Warner-Lambert Company
    Inventors: Steven B. Silbering, Russell U. Nesbitt, Mahdi B. Fawzi
  • Patent number: 4499068
    Abstract: Oral hygiene formulations incorporating N.sup.G -alkyl derivatives of arginine, or the pharmaceutically acceptable salts thereof, optionally in combination with fluoride compounds, are effective in combatting microorganisms, inhibiting acid production and reducing dental caries.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: February 12, 1985
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Steven B. Silbering, Tibor Sipos
  • Patent number: 4499067
    Abstract: Oral hygiene formulations incorporating N.sup.G -acyl derivatives of arginine, or the pharmaceutically acceptable salts thereof, optionally in combination with fluoride compounds, are effective in combatting microorganisms, inhibiting acid production and reducing dental caries.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: February 12, 1985
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Steven B. Silbering, Tibor Sipos
  • Patent number: 4477429
    Abstract: Oral hygiene formulations incorporating N.sup..alpha. -alkyl derivatives of arginine, or the pharmaceutically acceptable salts thereof, optionally in combination with fluoride compounds, are effective in combatting microorganisms, inhibiting acid production and reducing dental caries.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: October 16, 1984
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Steven B. Silbering, Tibor Sipos
  • Patent number: 4477428
    Abstract: Oral hygiene formulations incorporating N.sup..alpha.,N.sup.G -diacyl derivatives of arginine, or the pharmaceutically acceptable salts thereof, optionally in combination with fluoride compounds, are effective in combatting microorganisms, inhibiting acid production and reducing dental caries.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: October 16, 1984
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Steven B. Silbering, Tibor Sipos