Patents by Inventor Steven B. Zimmerman

Steven B. Zimmerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MANUFACTURING A PRODUCT USING CAUSAL MODELS
    Publication number: 20250036112
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for optimizing a process of manufacturing a product. In one aspect, the method comprises repeatedly performing the following: i) selecting a configuration of input settings for manufacturing a product, based on a causal model that measures causal relationships between input settings and a measure of a quality of the product; ii) determining the measure of the quality of the product manufactured using the configuration of input settings; and iii) adjusting, based on the measure of the quality of the product manufactured using the configuration of input settings, the causal model.
    Type: Application
    Filed: October 16, 2024
    Publication date: January 30, 2025
    Inventors: Brian E. Brooks, Gilles J. Benoit, Peter O. Olson, Tyler W. Olson, Himanshu Nayar, Frederick J. Arsenault, Nicholas A. Johnson, Brett R. Hemes, Thomas J. Strey, Jonathan B. Arthur, Nathan J. Herbst, Aaron K. Nienaber, Sarah M. Mullins, Mark W. Orlando, Cory D. Sauer, Timothy J. Clemens, Scott L. Barnett, Zachary M. Schaeffer, Patrick G. Zimmerman, Gregory P. Moriarty, Jeffrey P. Adolf, Steven P. Floeder, Andreas Backes, Peter J. Schneider, Maureen A. Kavanagh, Glenn E. Casner, Miaoding Dai, Christopher M. Brown, Lori A. Sjolund, Jon A. Kirschhoffer, Carter C. Hughes
  • Stimulation of enzymatic ligation of DNA by high concentrations of nonspecific polymers
    Patent number: 4582802
    Abstract: DNA ligase activity is strongly accelerated in the presence of high concentrations of non-specific polymers, with an accompanying change in product distribution characteristics. The rate of blunt-end ligation of DNA substrate by T4 DNA ligase is particularly affected, with a product shift from closed circular species to linear oligomers. The method provides a way to increase the rate of enzymatic DNA ligation and the size of the linear products. It may be useful when preparing large amounts of polymers by ligation of oligomers or when ligating amounts of DNA or deoxyribooligomers so low in concentration that a reduced yield would otherwise result.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: April 15, 1986
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Steven B. Zimmerman, Barbara H. Pheiffer