Patents by Inventor Steven Ballet

Steven Ballet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • G PROTEIN PEPTIDOMIMETICS
    Publication number: 20240083958
    Abstract: The present invention relates to G protein peptidomimetics capable of stabilizing a GPCR in an active conformational state. The G protein peptidomimetics are derived from the G protein epitope interacting with the GPCR, in particular from the C-terminus of the as helix comprising the amino acid sequence FNDCRDIIQRMHLRQYELL (SEQ ID NO:117). The invention further provides complexes of the G protein peptidomimetics and a GPCR, fusion polypeptides of a GPCR and the G protein peptidomimetics and compositions comprising the same. Further disclosed herein are uses of the G protein peptidomimetics, complexes, fusion polypeptides and compositions for determining the structure of the GPCR conformer and for screening for compounds capable of specifically binding to the GPCR conformer.
    Type: Application
    Filed: December 20, 2021
    Publication date: March 14, 2024
    Inventors: Steven Ballet, Charlotte Martin, Morgane Mannes
  • HYBRID MU OPIOID RECEPTOR AND NEUROPEPTIDE FF RECEPTOR BINDING MOLECULES, THEIR METHODS OF PREPARATION AND APPLICATIONS IN THERAPEUTIC TREATMENT
    Publication number: 20210002231
    Abstract: Molecules binding the mu opioid receptor (MOR) and the neuropeptide FF receptor (NPFFR), in particular molecules having a MOR agonist and NPFFR modulatory activity, and pharmaceutical compositions useful in the treatment of pain and/or hyperalgesia.
    Type: Application
    Filed: March 11, 2019
    Publication date: January 7, 2021
    Inventors: Frédéric Simonin, Armand Drieu la Rochelle, Frédéric Bihel, Steven Ballet
  • HYDROGEL-FORMING COMPOSITION FOR CONTROLLED RELEASE
    Publication number: 20200246472
    Abstract: The present invention provides peptide hydrogelators capable of forming hydrogels as carriers of active ingredients and acting as sustained or controlled release drug delivery systems.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 6, 2020
    Inventors: Charlotte Martin, Annemieke Madder, Steven Ballet, Richard Hoogenboom
  • Hydrogel-forming peptides
    Patent number: 10526371
    Abstract: Provided are hydrogel-forming peptides that comprise at least one dyad of hydrophobic amino acid residues in which one is a ?3- or ?2-homo amino acid residue. The hydrogels derived from these peptides can be loaded with biological materials and can be used in physiological conditions.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: January 7, 2020
    Assignees: Universiteit Gent, Vrije Universiteit Brussel
    Inventors: Richard Hoogenboom, Annemieke Madder, Steven Ballet
  • HYDROGEL-FORMING PEPTIDES
    Publication number: 20180201648
    Abstract: Provided are hydrogel-forming peptides that comprise at least one dyad of hydrophobic amino acid residues in which one is a ?3- or ?2-homo amino acid residue. The hydrogels derived from these peptides can be loaded with biological materials and can be used in physiological conditions.
    Type: Application
    Filed: July 13, 2016
    Publication date: July 19, 2018
    Inventors: Richard Hoogenboom, Annemieke Madder, Steven Ballet