Abstract: A method for reworking an electrically conductive layer of a composite skin is disclosed in which a patch replaces the altered section of the electrically conductive layer. The method is performed by removing a portion of the electrically conductive layer to reveal the underlying composite skin. A patch is formed, having an electrically conductive section coupled to an adhesive having a low dielectric breakdown strength, and is then introduced over the underlying composite skin such that the adhesive layer covers the underlying composite skin and overlaps an unremoved portion of the electrically conductive layer. The patch is applied such that the electrically conductive section within the patch covers the adhesive layer and overlaps the unremoved section of the electrically conductive layer. The adhesive layer preferably has a low dielectric breakdown strength, so that electricity from lightning which strikes the composite skin may be conducted through the adhesive.

Abstract: A method for reworking an electrically conductive layer of a composite skin is disclosed in which a patch replaces the altered section of the electrically conductive layer. The method is performed by removing a portion of the electrically conductive layer to reveal the underlying composite skin. A patch is formed, having an electrically conductive section coupled to an adhesive having a low dielectric breakdown strength, and is then introduced over the underlying composite skin such that the adhesive layer covers the underlying composite skin and overlaps an unremoved portion of the electrically conductive layer. The patch is applied such that the electrically conductive section within the patch covers the adhesive layer and overlaps the unremoved section of the electrically conductive layer. The adhesive layer preferably has a low dielectric breakdown strength, so that electricity from lightning which strikes the composite skin may be conducted through the adhesive.

Abstract: Method and apparatus for providing an electrical energy dissipation path from an area of a composite structure. A bonding site may be prepared on the composite structure that surrounds the area, and an adhesive may be applied to the prepared bonding site. An electrical energy dissipation patch may be placed on the adhesive, a caul plate may be placed over the electrical energy dissipation patch, and a heat pack may be placed over the caul plate. A compaction force may be applied to the heat pack for affixing the electrical energy dissipation patch to the bonding site. The electrical energy dissipation patch may include inner and outer electrically non-conductive layers and an electrically conductive central layer, the electrically conductive central layer including an extended portion that is electrically connected to the composite structure when the electrical energy dissipation patch is affixed to the composite structure.

Abstract: A method for reestablishing the electrical continuity of an electrically conductive layer of a composite aircraft wing damaged by a lightning strike or other mechanical event is disclosed in which a copper patch replaced the damaged section of the electrically conductive layer contained. The repair is performed by first removing any surfacers, fasteners, and damaged electrically conductive layer to expose a portion of the underlying composite skin. A copper patch having a copper foil section coupled to an unsupported film adhesive is then introduced onto an underlying composite skin opening contained within an undamaged section of a copper foil grid and covered with resin-impregnated fiberglass material. The film adhesive and resin-impregnated fiberglass material are then cured and fasteners are then reinserted within the fiberglass material, copper patch and underlying composite skin. The surface of the composite wing is then reprimed and repainted to complete the repair.

Abstract: A fast line maintenance repair process for damaged composite structures includes the application of a pre-cured patch that uses a quick curing paste adhesive to bond the patch to the structure. The adhesive is cured at relatively low elevated temperatures provided by a chemical heat pack. The low temperature cure eliminates the need to dry out the part and permits the application of the repair in a hazardous environment. In a typical commercial airline application, airline maintenance personnel can install the repair at the flight gate. The repair is intended to restore the structure to a desired load capability in approximately one hour. The repair can be removed if need be with less overall damage than would occur upon removal of typical mechanically fastened repairs. All or some of the repair materials and tools can be provided in a portable kit.

Abstract: Isolated corepressor peptides derived from a nuclear receptor interacting motif of corepressor Nuclear Receptor Corepressor (NCoR) or Silencing Mediator of Retinoid and Thyroid receptors (SMRT) are provided which binds to nuclear receptor ligand binding domains. Methods of using these peptides to evaluating selectivity of a ligand for a nuclear receptor subtype and quantitatively profiling selectivity of a test compound for a nuclear receptor are also provided.

Abstract: Methods of identifying compounds that interact with ERR? and are useful in the treatment of ERR?- and ER-mediated diseases, risk factors, and conditions are provided. Pharmaceutical compositions containing compounds that interact directly with ERR? and methods of using these compositions in the treatment of ERR?- and ER-mediated diseases, risk factors, and conditions are also provided.