Abstract: Techniques discussed herein relate to improved data recovery techniques within cloud computing environments. The disclosed techniques utilize consistency groups that are identified for volumes corresponding to a compute instance. A plurality of resource identifiers uniquely identifying a respective cloud computing resource of the cloud computing environment can be maintained. A cloud computing instance corresponding to a resource identifier may be identified and volume metadata associated with that resource identifier is obtained. The volume metadata identifying at least one of a block volume or boot volume. A consistency group is generated for the identified volume devices for the computing instance and one or more schedules can be generated with which various snapshots of the volume devices of the group are to be subsequently generated.

Abstract: Techniques discussed herein relate to improved data recovery techniques within cloud computing environments. The disclosed techniques utilize consistency groups that are identified for volumes corresponding to a compute instance. A plurality of resource identifiers uniquely identifying a respective cloud computing resource of the cloud computing environment can be maintained. A cloud computing instance corresponding to a resource identifier may be identified and volume metadata associated with that resource identifier is obtained. The volume metadata identifying at least one of a block volume or boot volume. A consistency group is generated for the identified volume devices for the computing instance and one or more schedules can be generated with which various snapshots of the volume devices of the group are to be subsequently generated.

Abstract: Image analytics systems, methods, and computer program products to autonomously analyze an image to identify and detect features in the image, such as the horizon, and/or identify and detect objects of interest therein, such as, smoke or possible smoke. The image is captured, for example, by RGB cameras, and depicts a scene to be analyzed. The intelligent image analytic system is configured to provide alerts and/or other information to one or more concerned parties and/or computing systems to take an appropriate response.

Abstract: Data objects can be migrated, while live, to virtualized clustered storage arrays in an efficient manner to allow for efficient transition from non-clustered storage to the virtualized clustered storage arrays. A data migration specification indicates data objects to be migrated and parameters for the migration. The parameters include a source of a data object, a destination of the data object in the virtualized clustered storage arrays, and a transfer space. A migration engine validates and parses the data migration specification. For each unique association of source, destination, and transfer space, the migration engine instantiates a migration process that drives and monitors migration of the corresponding data object. The migration processes operate in parallel for migration of the specified data objects into the virtualized clustered storage arrays.

Abstract: Data objects can be migrated, while live, to virtualized clustered storage arrays in an efficient manner to allow for efficient transition from non-clustered storage to the virtualized clustered storage arrays. A data migration specification indicates data objects to be migrated and parameters for the migration. The parameters include a source of a data object, a destination of the data object in the virtualized clustered storage arrays, and a transfer space. A migration engine validates and parses the data migration specification. For each unique association of source, destination, and transfer space, the migration engine instantiates a migration process that drives and monitors migration of the corresponding data object. The migration processes operate in parallel for migration of the specified data objects into the virtualized clustered storage arrays.

Abstract: Data objects can be migrated, while live, to virtualized clustered storage arrays in an efficient manner to allow for efficient transition from non-clustered storage to the virtualized clustered storage arrays. A data migration specification indicates data objects to be migrated and parameters for the migration. The parameters include a source of a data object, a destination of the data object in the virtualized clustered storage arrays, and a transfer space. A migration engine validates and parses the data migration specification. For each unique association of source, destination, and transfer space, the migration engine instantiates a migration process that drives and monitors migration of the corresponding data object. The migration processes operate in parallel for migration of the specified data objects into the virtualized clustered storage arrays.

Abstract: Compounds having the formula I wherein Z, Z1 Z2 Z3, R3a, R3b and Rb and as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

Abstract: Data objects can be migrated, while live, to virtualized clustered storage arrays in an efficient manner to allow for efficient transition from non-clustered storage to the virtualized clustered storage arrays. A data migration specification indicates data objects to be migrated and parameters for the migration. The parameters include a source of a data object, a destination of the data object in the virtualized clustered storage arrays, and a transfer space. A migration engine validates and parses the data migration specification. For each unique association of source, destination, and transfer space, the migration engine instantiates a migration process that drives and monitors migration of the corresponding data object. The migration processes operate in parallel for migration of the specified data objects into the virtualized clustered storage arrays.

Abstract: Articles and methods of manufacture are provided for using laser energy in an automated bonding machine to effect laser welding of ribbons to electronic components, particularly conductive ribbons comprising titanium for microelectronic circuits. Bonding and connection of microelectronic circuits with discrete heating avoids heat damage to peripheral microelectronic components. Bonding of flexible materials and low-resistance materials are possible, and are less dependant on substrate and terminal stability in comparison to other bonding methods. The ribbon-connections can forgo the use of blocks, bond pads, and bond pad arrays for attaching ribbon to a printed wiring board. Profile height of the ribbon-connection is decreased and the density of ribbons and bonding sites can be increased compared to ribbon-connections employing bonding pads.

Abstract: A system includes a storage engine node that includes a processor and a memory coupled to the processor. The memory stores a protocol mapper executable by the processor to convert storage access requests from a local storage protocol to a cloud storage protocol.

Abstract: Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Abstract: Articles and methods of manufacture are provided for using laser energy in an automated bonding machine to effect laser welding of ribbons to electronic components, particularly conductive ribbons comprising titanium for microelectronic circuits. Bonding and connection of microelectronic circuits with discrete heating avoids heat damage to peripheral microelectronic components. Bonding of flexible materials and low-resistance materials are possible, and are less dependant on substrate and terminal stability in comparison to other bonding methods. The ribbon-connections can forgo the use of blocks, bond pads, and bond pad arrays for attaching ribbon to a printed wiring board. Profile height of the ribbon-connection is decreased and the density of ribbons and bonding sites can be increased compared to ribbon-connections employing bonding pads.

Abstract: The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R1, R2, R3, R4, R5, R6, Ra-Rd, n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.

Abstract: Compounds of Formulas Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Abstract: Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Abstract: There is provided a CRF receptor antagonist comprising a compound of the formula (I): A-W—Ar??(I) wherein, A is a group represented by the formula (A1) or (A2): (wherein, ring Aa is a 5- or 6-membered ring which may be further substituted; ring Ab is a 5- or 6-membered ring which may be further substituted; ring Ac is a 5- or 6-membered ring which may be substituted; R1 is optionally substituted alkyl, substituted amino, substituted hydroxy, etc.; X is carbonyl, —O—, —S—, etc.; Y1, Y2 and Q are independently optionally substituted carbon or nitrogen; is a single or double bond); W is a bond, optionally substituted methylene, optionally substituted imino, —O—, —S—, etc.; Ar is optionally substituted aryl or optionally substituted heteroaryl; or a salt thereof or a prodrug thereof.

Abstract: Scaleable bacterial injection, aeration and filtration system to effectively control microbial community function of aquatic systems. The present invention is a substantially simplified system with respect to handling growth and dispersion of microorganisms in solution and is also adaptable to many different end-use applications, including treatment of ornamental fish and aquaculture, pond and streams and sewage treatment systems. Initial microorganism materials are provided in the form of aqueous suspensions, which are incorporated into a large volume of water in a vessel. Microorganisms are entrapped inside a carrier that serves as a physical enclosure for cell retention. It has a porous structure to facilitate the diffusion of substances, such as ammonia, nitrate, nutrients, fuels and organic carbon, into its internal void volume, where substrate reduction is accomplished by entrapped cells.

Abstract: A compound of the formula (I): or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.

Abstract: The present invention relates to selective NK-1 receptor antagonists of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of disorders associated with an excess of tachykinins.

Abstract: A method and system for assembling a component within a medical device that includes a test station to determine whether the component is in a predetermined working state, and an orientation sensor to sense an orientation vector of the component. A first sensor senses a position of the component within an aperture of the device and plots a weld path associated with the component. An installation head obtains the component, advances the component between the test station, the orientation sensor and the first sensor, and through the aperture, and a weld head generates a weld along a generated weld path.