Abstract: A package having an additive that does not adhere to a medical device enclosed therein.

Abstract: The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry.

Abstract: A package having an additive that does not adhere to a medical device enclosed therein.

Abstract: The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry.

Abstract: The present invention is directed to medical devices, pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.

Abstract: The present invention is directed to microdispersions and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry, and a synthetic, bioabsorbable, biocompatible polymeric wax comprising the reaction product of a polybasic acid or derivative thereof, a fatty acid and a polyol, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.

Abstract: The present invention is directed to microdispersions and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry, and a synthetic, bioabsorbable, biocompatible polymeric wax comprising the reaction product of a polybasic acid or derivative thereof, a fatty acid and a polyol, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.

Abstract: The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry.

Abstract: A fuel injector includes a spool control valve, a plunger which moves in a fuel pressure chamber between retracted and full stroke positions. The fuel injector may include a spill port for spilling fuel from the fuel pressure chamber, the spill port being open at the start and closed by the translating motion of the plunger to delay the start of injection. The fuel injector chamber may further include a control port which is closed at the start of plunger motion and is opened by the plunger to connect the pressure chamber to a needle back chamber to bias the needle valve closed. The needle back chamber becomes isolated from the pressure chamber by further movement of the plunger and includes a pressure control passage to allow the pressure therein to decay upon control port closure, thereby effecting split injection or rate shaping.

Abstract: The present invention is directed to medical devices, pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.

Abstract: The present invention provides surgical article and suture coated with bioabsorbable microdispersions which contains a fluid carrier that is a liquid polymer and a particular material.

Abstract: The present invention provides injectable, bioabsorbable liquid copolymers suitable for use as a soft tissue repair or augmentation material in animals comprising a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and liquid polymers of a plurality of first lactone and second lactone repeating units; wherein the first lactone repeating units are selected from the group consisting of .epsilon.-caprolactone repeating units, trimethylene carbonate repeating units, ether lactone repeating units (which for the purpose of this invention shall mean 1,4-dioxepan-2-one and 1,5-dioxepan-2-one) and combinations thereof and the second lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units (which for the purpose of this invention are defined to be L-lactide, D-lactide, or D,L-lactide repeating units), p-dioxanone repeating units and combinations thereof.

Abstract: The present invention provides injectable, bioabsorbable microdispersions suitable for use as a soft tissue repair or augmentation material in animals comprising a fluid carrier that is a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and other liquid polymers; and a particulate material. Additionally, the present invention also discloses methods of using these microdispersions for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.

Abstract: Absorbable binary and tertiary blends of homopolymers and copolymers of poly(lactide), poly(glycolide), poly(.epsilon.-caprolactone), and poly(p-dioxanone) are described. The blends when used to manufacture medical devices exhibit shape retention, dimensional stability and palpability without loss of the strength, stiffness and BSR found for poly(lactide) homopolyers and/or poly(lactide-co-glycolide) copolymers.

Abstract: This invention provides various copolymers comprising a first repeating unit of the chemical formula: ##STR1## in which R.sub.1 and/or R.sub.2 are alkyl groups and a second repeating units generally having the chemical formula: ##STR2## and combinations of two or more thereof wherein R is a hydrogen atom or a methyl group and the first repeating unit is less than 45 weight percent of the total weight of the copolymer. This invention also relates to use of these copolymers in the fabrication of absorbable surgical devices such as sutures and as coatings for medical devices. Additionally, described are blends and polyoxaesters containing the first repeating unit.

Abstract: Absorbable biocompatible polymer blends useful to manufacture medical devices. The blends have a first major phase including polymers such as poly(lactide homopolymers and poly(lactide-co-glycolide) copolymers and combination thereof. The blends have a second minor phase include copolymers of poly(.epsilon.-caprolactone-co-p-dioxanone).

Abstract: The present invention provides injectable, bioabsorbable microdispersions suitable for use as a soft tissue repair or augmentation material in animals comprising a fluid carrier that is a liquid polymer selected from the group consisting of liquid polymers and a particulate material. Additionally, the present invention also discloses methods of using these microdispersions for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.

Abstract: A composition of an absorbable polymer and a filler to increase the stiffness of the polymer is disclosed. The filler is a poly[succinimide], which is a bioabsorbable polymer that degrades into a nontoxic, simple amino acid. The composition can be melt processed to prepare medical and surgical devices, particularly those devices which are designed to penetrate bodily tissue or to withstand heavy loads. Typical surgical devices which can be made from the composition include surgical staples and ligating clips.

Abstract: This invention provides various copolymers comprising a repeating unit of the chemical formula:(CH.sub.2 CH.sub.2 CH.sub.2 OCH.sub.2 CO.sub.2)and other repeating units having a chemical formula selected from the group consisting of:(CHRCO.sub.2),([CH.sub.2 ].sub.5 CO.sub.2),(CH.sub.2 CH.sub.2 OCH.sub.2 CO.sub.2),(CH.sub.2 CH.sub.2 CH.sub.2 OCO.sub.2), andcombinations of two or mope thereof wherein R is a hydrogen atom or a methyl group and the first repeating unit is less than 45 weight percent of the total weight of the copolymer. This invention also relates to use of these copolymers in the fabrication of absorbable surgical devices such as sutures and as coatings for medical devices.

Abstract: A composition of an absorbable polymer and a filler to increase the stiffness of the polymer is disclosed. The filler is a poly[succinimide], which is a bioabsorbable polymer that degrades into a nontoxic, simple amino acid. The composition can be melt processed to prepare medical and surgical devices, particularly those devices which are designed to penetrate bodily tissue or to withstand heavy loads. Typical surgical devices which can be made from the composition include surgical staples and ligating clips.