Abstract: A bedsore reduction system for beds includes a generally rectangular base plate, a mattress support plate and a diagonal connecting plate extending between said base plate and said mattress support plate and pivotably connecting the opposite side edges of the base plate and the mattress support plate. An inflatable upper wedge-shaped air chamber having a generally triangular cross-sectional shape is positioned between the mattress support plate and the diagonal connecting plate and an inflatable lower wedge-shaped air chamber having a generally triangular cross-sectional shape is positioned between the base plate and the diagonal connecting plate. Finally, a controllable inflation device such as a set of air pumps is operatively connected to the upper and lower wedge-shaped air chambers for inflating and deflating them such that the mattress support plate is adjustable in the yaw orientation relative to horizontal thereby tilting a mattress supported on thereon for prevention of bedsores.