Abstract: A heat exchanger including an array of tubes and fins is configured to reside in a centrifugal fan enabling the centrifugal fan to operate as a cooling and or heating source.

Abstract: A portable system for transferring liquids such as fuels from a first tank to a second tank. The first tank may be, for example, a railcar and the second tank a transport trailer. The portable system is separated into multiple compartments with an engine compartment and a pump compartment. A wall separates the engine and pump compartments and may be sealed to prevent the passage of air or vapor therethrough. The pump is utilized to transfer liquid from the first tank to the second tank.

Abstract: A switch element includes a switch device having a drain, a source and a plurality of gates, and at least one additional interconnect located between the plurality of gates, the additional interconnect operative to establish a constant potential between the at least two gates.

Abstract: Method and apparatus for ablating target tissue adjacent pulmonary veins of a patient. A clamping ablation tool can include an upper arm having an upper neck, a link assembly, and an upper actuator. The link assembly can include a distal electrode and a proximal electrode. The clamping ablation tool can include a lower arm that mates with the upper arm. The lower arm can include a lower neck, a distal jaw, and a lower actuator. The distal jaw can include a jaw electrode, and the lower actuator can control movement of the distal jaw.

Abstract: A port assembly includes a valve housing with an inlet opening, a valve disposed in the valve housing to control access through the inlet opening, and a base joined to the valve housing and having a bore therethrough. The bore has a closed end defined by a frangible barrier, and a pushrod is disposed in the bore between the valve and the frangible barrier, axial movement of the pushrod causing rupture of the frangible barrier. The port assembly may be used in a fluid container that includes a receptacle for retaining a fluid, and at least one conduit in communication with the receptacle. The at least one conduit is defined, at least in part, by a port assembly.

Abstract: A portable, small-footprint laser device contains one or more housings in which a laser energy source and an optical arrangement are disposed. The housing produces a laser beam spot that may be rotated and scanned to apply laser energy to a target area. The laser device receives treatment parameters and uses them to program a treatment regimen in which activation and movement of the housings is automated. The laser device may be used to apply a treatment regimen to a patient's hands or feet that are infected by Onychomycosis. In the treatment regimen, certain wavelengths of laser energy are applied at a predetermined duration. The treatment may be repeated, and a topical anti-fungal medication may be applied to aid in the efficacy of the treatment.

Abstract: Methods and compositions containing huperzine are used to prevent and alleviate seizures. The invention is also directed to methods and compositions for using huperzine for the prevention and/or treatment of orthostatic hypotension.

Abstract: A memory bus with a first bus segment coupled to a memory controller that includes control logic and a first memory device, a second bus segment coupled to a second memory device, and a switch between the first bus segment and the second bus segment. The control logic outputs control information to the switch to selectively decouple the first bus segment and the second bus segment to effect a change in the length of the memory bus to enable data transfer with respect to the first memory device at a first data rate. Additionally, the control logic may output control information to the switch to selectively couple the first bus segment and the second bus segment to increase the length of the memory bus to enable data transfer with respect to the second memory device at a second data rate that is slower than the first data rate.

Abstract: An eccentric rail mounting system is disclosed. In various embodiments, this system comprises an eccentric rail nut for off-center mounting of a rail on a firearm. The eccentric rail nut has an exterior surface that defines a central axis of the nut and a main bore that defines a central axis of the main bore that is displaced from the central axis of the nut. Components and methods are disclosed in a variety of embodiments.

Abstract: A method predicts and quantifies the threat posed to a human-operated device based on an optimal device trajectory through a constraint-bounded corridor. A model of the device together with a model of anticipated hazards and the current state of both the device and the hazards are used to iteratively generate an optimal device trajectory through a constraint-bounded corridor or region within state space. Device dynamics are forward-simulated over a time horizon. A method generates a threat assessment metric from the resulting sequence of optimal vehicle states. This threat assessment may be used to devise various types and levels of operator assistance. The human operator can control the device within a safe corridor or region. Threat assessment is based on the nearness of successive optimal trajectory predictions to limits of safe device handling rather than on deviation from a predefined path.

Abstract: Elongated side rails for attachment to a sidewall of a truck cargo box as a portion of a tonneau cover assembly. Each assembly includes a flexible cover that can be operatively secured to side rails. One side rail includes a securing portion that can be operatively connected to the sidewall; an inclined portion extending from the securing portion, the inclined portion having first and second sides; a connecting member extending downwardly away from the inclined portion from a position located between the first and second sides; and a longitudinal portion extending from the connecting member opposite the inclined portion. To secure the cover to the side rails, hook fastener is preferably attached to loop fastener on the cover. One preferred side rail has a ridge to prevent premature engagement of the fasteners. Another preferred side rail has directional hook fastener to prevent premature engagement of the fasteners.

Abstract: The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The present invention further provides polynucleotide and polypeptide sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use.

Abstract: The present invention provides a pre-formed bi-layer thermoplastic film or sheet comprising a first surface layer made of acid copolymers, or ionomers, or combinations thereof and a second surface layer made of ethylene acrylate ester copolymers, a solar cell pre-laminate assembly comprising the same, and a simplified process for manufacturing a solar cell module derived therefrom.

Abstract: A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.

Abstract: A tonneau cover apparatus for securing a flexible cover about a cargo box of a pickup truck. The apparatus comprises the cover and a support frame for attachment to the cargo box. The frame has two opposing side rails, each of which has a lock engaging surface. The support frame further includes a pair of securing plate engagement members, each of which is secured to one of the respective opposing side rails. The apparatus further comprises a flexible cover securing plate attached to the cover. The flexible cover securing plate includes a channel and least one locking member. Each locking member is secured within the channel and each respective locking member is engagable with the lock engaging surface of the respective side rail such that the flexible cover securing plate is prevented from disengaging with respect to the respective side rail when it is in a first position.

Abstract: The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.

Abstract: System, device and method for ablating target tissue adjacent pulmonary veins of a patient through an incision. An ablation device can include a hinge including a cam assembly, a moving arm, a floating jaw, and a lower jaw. Fingers can engage the floating jaw to hold the floating jaw in a first position with respect to the moving arm. Some embodiments of the invention can provide an ablation device including a central support, an upper four-bar linkage coupled to the central support, an upper jaw coupled to the upper linkage, a lower four-bar linkage coupled to the central support, and a lower jaw coupled to the lower linkage. Some embodiments of the invention can provide an ablation device having an upper jaw including a first cannula connection and a lower jaw including a second cannula connection. The system can include a first catheter coupled to the first cannula connection and a second catheter coupled to the second cannula connection.

Abstract: Lapping guides for use in fabrication of a magnetic recording head are provided. The lapping guides comprise a first differential electronic lapping guide (ELG) disposed in a first layer of the magnetic recording head. The first differential ELG has a first resistive element and a second resistive element between which is disposed a first common electrical lead. The lapping guides further comprise a second differential ELG disposed in a second layer of the magnetic recording head. The second differential ELG has a third resistive element and a fourth resistive element between which is disposed a second common electrical lead. The first and second differential ELGs share a common ground and a common current injection source. Remaining lapping distances at the first and second layers of the magnetic recording head are determined by measuring changing voltages across the first, second, third and fourth resistive elements, respectively.

Abstract: A storage cartridge for dispensing biosensors used in the determination of an analyte in body fluid comprises a hollow body for housing a stack of biosensors having an open top, a flexible conveying member disposed over the open top of the body, the flexible conveying member having an aperture formed therein for receiving a biosensor from the stack of biosensors, a plate adapted to press the sliding conveying member against the open top to form a substantially moisture-impervious seal around the open top of the body and to permit the conveying member to slide between the plate and the open top, and a biasing mechanism the stack of biosensors towards the open top.

Abstract: Embodiments of methods for creating and taking a driving tour using information derived from crowd sourcing are disclosed herein. A method includes, but is not limited to accessing an Internet website that is configured to enable a user to compose a driving tour based in part on the information derived from crowd sourcing and in part on a user-specified criterion. The method further includes inputting the user-specified criterion into the Internet website. The method further includes creating the driving tour using the Internet website, the driving tour having a point of interest. The method further includes obtaining an electronic file from the Internet website containing the driving tour. The method further includes loading the electronic file into a mobile device. The method still further includes utilizing the mobile device and the electronic file to take the driving tour.