Patents by Inventor Steven Charlebois
Steven Charlebois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20210308342Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Applicants: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Rhonda Peck, Bhavin B. Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
-
Patent number: 11065368Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: GrantFiled: March 14, 2014Date of Patent: July 20, 2021Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLCInventors: Rhonda Peck, Bhavin Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
-
Patent number: 10426623Abstract: A hip stem prosthesis is provided for treating a deficient hip joint.Type: GrantFiled: April 7, 2017Date of Patent: October 1, 2019Assignee: Zimmer, Inc.Inventors: Natalia Fridshtand, Douglas W. Gabel, Steven Charlebois, David L. Glass, Steven Zawadzki, Jeffrey P. Matney
-
Publication number: 20190269808Abstract: Disclosed are methods for treating platelet compositions (e.g. platelet concentrates and/or platelet lysates) with electron beam radiation, where the compositions are in a frozen state during irradiation with the e-beam radiation. The methods can be conducted using e-beam radiation at doses effective to reduce the pathogen content of the compositions while retaining highly beneficial bioactivities of the compositions. Also disclosed are compositions preparable by the methods, and methods and compositions involving the use of the e-beam treated materials.Type: ApplicationFiled: December 20, 2018Publication date: September 5, 2019Applicant: Cook Regentec LLCInventors: Steven Charlebois, Sreedhar Thirumala
-
Patent number: 10328213Abstract: Methods and apparatus are provided for treating tissue with apparatus that includes an priming portion for initiating a healing response in the tissue to be treated, and which delivers a bioactive agent during or after preparing tissue adjacent the apparatus, as by generating or aiding a healing, regeneration or repair response in the tissue. The priming portion may comprise an abrasive surface, fluid ejection ports, and/or stimulation by electrical, thermal, or light energy.Type: GrantFiled: March 14, 2014Date of Patent: June 25, 2019Assignee: Muffin IncorporatedInventors: Richard B. Sisken, Ryan Pruchnic, Frank J. Fischer, Jr., Steven Charlebois
-
Patent number: 9993580Abstract: Osteogenic compositions include a decellularized extracellular matrix tissue and bone morphogenic protein, preferably BMP-2. The compositions make beneficial use of the BMP, which can be used at relatively low doses and can bind to native components (e.g., native sulfated glycosaminoglycans such as heparin and/or heparan sulfate) remaining in the decellularized extracellular matrix tissue. Methods for preparation and use of such compositions are also described. The compositions and related methods can be used in the treatment of diseased or damaged bone tissue.Type: GrantFiled: March 2, 2016Date of Patent: June 12, 2018Assignee: Muffin IncorporatedInventors: Shelley Lynn Scoville, Amanda F. Taylor, Steven Charlebois, Christine M. Steinhart, Neal E. Fearnot
-
Patent number: 9956384Abstract: Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon.Type: GrantFiled: January 23, 2015Date of Patent: May 1, 2018Assignee: COOK MEDICAL TECHNOLOGIES LLCInventors: Steven Charlebois, Sara Sherman
-
Patent number: 9931439Abstract: Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. The medical graft materials and devices can have a first outer surface and a second outer surface and can define an internal chamber between the first outer surface and the second outer surface. The medical graft materials and devices can also have at least one region of the graft material interrupting the chamber and surrounded by the chamber. Also described are methods for making and using these medical graft materials and devices.Type: GrantFiled: November 25, 2013Date of Patent: April 3, 2018Assignees: Cook Biotech Incorporated, Muffin IncorporatedInventors: Neal E. Fearnot, Michael C. Hiles, Jeremy Metz, F. Joseph Obermiller, Andrew J. Kaucher, Steven Charlebois
-
Publication number: 20170209276Abstract: A hip stem prosthesis is provided for treating a deficient hip joint.Type: ApplicationFiled: April 7, 2017Publication date: July 27, 2017Inventors: Natalia Fridshtand, Douglas W. Gabel, Steven Charlebois, David L. Glass, Steven Zawadzki, Jeffrey P. Matney
-
Patent number: 9656358Abstract: A method for attaching a porous metal layer to a dense metal substrate, wherein the method is particularly useful in forming orthopedic implants such as femoral knee components, femoral hip components, and/or acetabular cups. The method, in one embodiment thereof, comprises providing a solid metal substrate; providing a porous metal structure; contouring a surface of the porous metal structure; placing the porous structure against the substrate such that the contoured surface of the porous metal structure is disposed against the substrate, thereby forming an assembly; applying heat and pressure to the assembly in conjunction with thermal expansion of the substrate in order to metallurgically bond the porous structure and the substrate; and removing mass from the substrate after the porous structure is bonded to the substrate, thereby finish processing the assembly.Type: GrantFiled: April 15, 2013Date of Patent: May 23, 2017Assignee: Zimmer, Inc.Inventors: Steven Charlebois, Leslie N. Gilbertson, Michael E Hawkins, Dana Medlin, H. Ravindranath Shetty, Steven Zawadzki
-
Patent number: 9636227Abstract: A hip stem prosthesis is provided for treating a deficient hip joint.Type: GrantFiled: October 9, 2014Date of Patent: May 2, 2017Assignee: Zimmer, Inc.Inventors: Natalia Fridshtand, Douglas W. Gabel, Steven Charlebois, David L. Glass, Steven Zawadzki, Jeffrey P. Matney
-
Publication number: 20170007754Abstract: An endovascular assembly for improving vessel compliance by reducing the blood pressure needed to eject a given volume of blood. The assembly comprises a first expandable container, a balloon for example, positioned in the vascular system. The first container has a variable volume in response to blood flow in the vessel, and is fixed to at least one expandable attachment member. When the attachment member is expanded inside of the vasculature, the attachment member is preferably fixed inside the vessel. The assembly further comprises a second container, preferably having a fixed volume that forms a closed fluid system when fluidly connected to the first container. The connection between the first and second container permits a change in volume in the first container to flow fluid into the second container. The second container can be placed in a different location inside of the patient, preferably outside of the vessel.Type: ApplicationFiled: July 6, 2015Publication date: January 12, 2017Inventors: Charles F. Babbs, Steven Charlebois, Kenneth Haselby, Jarin Kratzberg, Justin Metcalf, Richard B. Sisken
-
Publication number: 20160346432Abstract: Described are sheet-form cell growth scaffold particles, and methods for preparing and using them. The particles can be prepared using punch or other cutting operations to provide relatively uniform populations of particles in terms of shape and size, desirably employing a stack of multiple sheets of starting material and multiple punches. Cellularized grafts and/or cell conditioned media can be prepared using the sheet-form cell growth scaffold particles.Type: ApplicationFiled: May 27, 2016Publication date: December 1, 2016Inventors: Shelly J. Zacharias, Steven Charlebois, Charles Leland Baxter
-
Publication number: 20160263282Abstract: Osteogenic compositions include a decellularized extracellular matrix tissue and bone morphogenic protein, preferably BMP-2. The compositions make beneficial use of the BMP, which can be used at relatively low doses and can bind to native components (e.g., native sulfated glycosaminoglycans such as heparin and/or heparan sulfate) remaining in the decellularized extracellular matrix tissue. Methods for preparation and use of such compositions are also described. The compositions and related methods can be used in the treatment of diseased or damaged bone tissue.Type: ApplicationFiled: March 2, 2016Publication date: September 15, 2016Inventors: Shelly L. Wallace, Amanda F. Taylor, Steven Charlebois, Christine M. Steinhart, Neal E. Fearnot
-
Patent number: 9149585Abstract: A medical device and a method of treating stress urinary incontinence are provided. The device includes a cannula with a plurality of apertures. A plurality of needles is disposed within a lumen of the cannula. A handle includes a housing and a shifter mechanism to translate the plurality of needles from a first position in which the needles are disposed within the lumen of the cannula, to a second position in which a distal portion of each needle extends out of the lumen through respective apertures. The handle also includes a slot including a transversal track defining a potential range of rotational motion of the shifter mechanism with respect to the housing, and a plurality of longitudinal tracks defining a potential range of translational motion of the shifter mechanism with respect to the housing. The shifter mechanism may also rotate the cannula with respect to the handle.Type: GrantFiled: April 19, 2013Date of Patent: October 6, 2015Assignee: Cook Medical Technologies LLCInventors: Jennifer Rodenberg, William Bourdeau, Charles Baxter, Steven Charlebois, Zach Wagner, Sara Sherman
-
Publication number: 20150209483Abstract: One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.Type: ApplicationFiled: April 10, 2015Publication date: July 30, 2015Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Keith R. Milner, James M. Carlson, Steven Charlebois, Krista N. Gearhart, Richard A. Swift
-
Publication number: 20150209558Abstract: Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon.Type: ApplicationFiled: January 23, 2015Publication date: July 30, 2015Inventors: Steven Charlebois, Sara Sherman
-
Publication number: 20150065425Abstract: Osteogenic compositions include a decellularized extracellular matrix tissue and bone morphogenic protein, preferably BMP-2. The compositions make beneficial use of the BMP, which can be used at relatively low doses and can bind to native components (e.g., native sulfated glycosaminoglycans such as heparin and/or heparan sulfate) remaining in the decellularized extracellular matrix tissue. Methods for preparation and use of such compositions are also described. The compositions and related methods can be used in the treatment of diseased or damaged bone tissue.Type: ApplicationFiled: September 2, 2014Publication date: March 5, 2015Inventors: Shelley L. Wallace, Amanda F. Taylor, Steven Charlebois, Christine M. Steinhart, Neal E. Fearnot
-
Publication number: 20150065947Abstract: Compositions and methods for treating diseased or damaged bone, preferably ischemic and/or necrotic bone, include the use of a combination of endothelial progenitor cells and mesenchymal stem cells, desirably also in conjunction with a collagenous extracellular matrix tissue. Methods for preparation of such compositions are also described.Type: ApplicationFiled: August 29, 2014Publication date: March 5, 2015Inventors: Shelley L. Wallace, Amanda F. Taylor, Steven Charlebois, Christine M. Steinhart, Neal E. Fearnot
-
Publication number: 20150025649Abstract: A hip stem prosthesis is provided for treating a deficient hip joint.Type: ApplicationFiled: October 9, 2014Publication date: January 22, 2015Inventors: Natalia Fridshtand, Douglas W. Gabel, Steven Charlebois, David L. Glass, Steven Zawadzki, Jeffrey P. Matney