Patents by Inventor STEVEN CHARLES LEY

STEVEN CHARLES LEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TPL-2/COT KINASE AND METHODS OF USE
    Publication number: 20020099169
    Abstract: It is shown that TPL-2 is responsible for phosphorylation of p105 and its resultant proteolysis, which leads to p50 Rel translocation to the nucleus. Accordingly, the invention provides TPL-2 as a specific regulator of the activation of NF&kgr;B, and thus as a modulator of inflammatory responses in which p105 is involved, and as a target for the development of compounds capable of influencing NF&kgr;B activation.
    Type: Application
    Filed: August 13, 1999
    Publication date: July 25, 2002
    Applicant: BASF AKTIENGESELLCHAFT
    Inventors: HAMISH JOHN ALLEN, RICHARD WOODWARD DIXON, JOANNE SARA KAMENS, DINELI WICKRAMASINGHE, YAJUN XU, MONICA POLIDORO BELICH, LELAND HERRIES JOHNSTON, STEVEN CHARLES LEY, ANDRES SALMERON