Patents by Inventor Steven Chu

Steven Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11409748
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for context scoring adjustments for candidate answer passages. In one aspect, a method includes scoring candidate answer passages. For each candidate answer passage, the system determines a heading vector that describes a path in the heading hierarchy from the root heading to the respective heading to which the candidate answer passage is subordinate; determines a context score based, at least in part, on the heading vector; and adjusts answer score of the candidate answer passage at least in part by the context score to form an adjusted answer score. The system then selects an answer passage from the candidate answer passages based on the adjusted answer scores.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: August 9, 2022
    Assignee: GOOGLE LLC
    Inventors: Nitin Gupta, Srinivasan Venkatachary, Lingkun Chu, Steven D. Baker
  • Patent number: 11369343
    Abstract: Nonlinear ultrasound imaging systems and methods are disclose. In one aspect, a nonlinear ultrasound imaging system includes a first transducer configured to transmit a first ultrasound signal along a scan line, a second transducer configured to sweep a second ultrasound signal along the scan line such that the first and second ultrasound signals intersect at a plurality of voxels, and a third transducer configured to receive echoes associated with interactions of the first and second ultrasound signals at the plurality of voxels. The nonlinear ultrasound imaging system further includes a processor configured to generate an ultrasound image based on the echoes.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: June 28, 2022
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yilei Li, Steven Chu
  • Patent number: 11273443
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: March 15, 2022
    Assignee: Visby Medical, Inc.
    Inventors: Boris Andreyev, Keith E. Moravick, Brian Ciopyk, Victor Briones, Gregory Loney, Adam De La Zerda, Jesus Ching, Steven Chu, David Swenson, Helen Huang, Colin Kelly
  • Publication number: 20220055032
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: October 22, 2021
    Publication date: February 24, 2022
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Publication number: 20220041926
    Abstract: An upconversion single molecule probe is provided that includes a core having a nanoparticle seed crystal, where the nanoparticle seed crystal is an upconversion seed crystal, a first shell enveloping the core, and a second shell enveloping the first shell.
    Type: Application
    Filed: May 9, 2019
    Publication date: February 10, 2022
    Inventors: Steven Chu, Qian Liu, Yunxiang Zhang, Chunte Peng
  • Publication number: 20210354131
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: September 11, 2020
    Publication date: November 18, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Publication number: 20210354132
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: October 14, 2020
    Publication date: November 18, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Patent number: 11167285
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: November 9, 2021
    Assignee: Visby Medical, Inc.
    Inventors: Boris Andreyev, Keith E. Moravick, Brian Ciopyk, Victor Briones, Gregory Loney, Adam De La Zerda, Jesus Ching, Steven Chu, David Swenson, Helen Huang, Colin Kelly
  • Publication number: 20210331159
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: August 23, 2018
    Publication date: October 28, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Publication number: 20210283616
    Abstract: An apparatus includes a substrate, a first heating element, and a second heating element. The substrate includes a first portion, a second portion, and a third portion that is between the first portion and the second portion. The first portion is characterized by a first thermal conductivity, the second portion is characterized by a second thermal conductivity, and the third portion is characterized by a third thermal conductivity. The third thermal conductivity is less than the first thermal conductivity and the second thermal conductivity. The first heating element is coupled to the first portion of the substrate, and is configured to produce a first thermal output. The second heating element is coupled to the second portion of the substrate, and configured to produce a second thermal output. The second thermal output is different from the first thermal output.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 16, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Brian CIOPYK, Victor BRIONES, Jonathan HONG, David SWENSON, Gregory LONEY, Adam DE LA ZERDA, Steven CHU
  • Publication number: 20210251612
    Abstract: Ultrasound imaging systems and methods with frequency (spectral) compounding for speckle reduction are disclosed. In one aspect, an ultrasound imaging system includes a transducer probe with interleaved transmit and receive arrays. The system may utilize ultrasound pulses having an optimized time-bandwidth product. In one aspect, a transducer probe with separate transmit and receive elements can enable transmission and reception of multiple ultrasound pulses, each centered at a different frequency, during the time of one A-scan. Thus, such a system can capture multiple independent speckle images without reducing overall B-mode framerate. In another aspect, the system may transmit a broadband pulse and may obtain separate speckle images by filtering the received echo using multiple spectral filters. The system may compound multiple images captured at different frequencies to provide speckle reduction.
    Type: Application
    Filed: December 18, 2020
    Publication date: August 19, 2021
    Inventors: Yilei Li, Steven CHU
  • Publication number: 20210237090
    Abstract: An apparatus includes a substrate, a first heating element, and a second heating element. The substrate includes a first portion, a second portion, and a third portion that is between the first portion and the second portion. The first portion is characterized by a first thermal conductivity, the second portion is characterized by a second thermal conductivity, and the third portion is characterized by a third thermal conductivity. The third thermal conductivity is less than the first thermal conductivity and the second thermal conductivity. The first heating element is coupled to the first portion of the substrate, and is configured to produce a first thermal output. The second heating element is coupled to the second portion of the substrate, and configured to produce a second thermal output. The second thermal output is different from the first thermal output.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Brian CIOPYK, Victor BRIONES, Jonathan HONG, David SWENSON, Gregory LONEY, Adam DE LA ZERDA, Steven CHU
  • Publication number: 20210219961
    Abstract: This disclosure relates to ultrasound imaging with reduced speckle. Ultrasound imaging with frequency compounding and angle compounding is disclosed. Techniques are disclosed to make ultrasound imaging with frequency and angle compounding more robust. One such technique is non-rigid image registration to align ultrasound images for angle compounding. Another disclosed technique includes selecting a subset of ultrasound images for non-rigid ultrasound image registration.
    Type: Application
    Filed: June 18, 2019
    Publication date: July 22, 2021
    Inventors: Noah Yuzo TOYONAGA, Yilei LI, Steven CHU
  • Publication number: 20210212668
    Abstract: This disclosure relates to combined frequency and angle compounding for speckle reduction in ultrasound imaging Such combined frequency and angle compounding can result in a multiplicative speckle reduction compared to using either frequency compounding or angle compounding alone. Compounding methods of this disclosure can make use of the full aperture of the ultrasound probe when acquiring individual images, hence there can be no compromise in resolution. In disclosed embodiments, ultrasound images can be obtained while an ultrasound probe is moving and the relative position and orientation of the ultrasound images can be determined from a measurement of the position and orientation of the ultrasound probe. Certain embodiments can correct for the movement and distortion of an object being imaged during the image acquisition.
    Type: Application
    Filed: May 21, 2019
    Publication date: July 15, 2021
    Inventors: Yilei LI, Steven CHU, Noah Yuzo TOYONAGA, James Y. JIANG, Alex E. CABLE
  • Publication number: 20210198795
    Abstract: An electrochemical gas conversion device is provided, that includes a flexible membrane formed in a sack-shape, where the membrane includes a gas permeable and liquid-impermeable membrane, where at least a portion of the flexible membrane is surrounded by a liquid electrolyte held by a housing, where the flexible membrane includes a gas interior, an electrically conductive catalyst coating on an exterior surface of the flexible membrane, where the flexible membrane and the electrically conductive catalyst coating are configured as a anode or a cathode, and an inlet/outlet tube configured to flow the gas to the interior, from the interior, or to and from the interior of the flexible membrane.
    Type: Application
    Filed: November 7, 2018
    Publication date: July 1, 2021
    Inventors: Yi Cui, Jun Li, Steven Chu
  • Patent number: 10987674
    Abstract: An apparatus includes a substrate, a first heating element, and a second heating element. The substrate includes a first portion, a second portion, and a third portion that is between the first portion and the second portion. The first portion is characterized by a first thermal conductivity, the second portion is characterized by a second thermal conductivity, and the third portion is characterized by a third thermal conductivity. The third thermal conductivity is less than the first thermal conductivity and the second thermal conductivity. The first heating element is coupled to the first portion of the substrate, and is configured to produce a first thermal output. The second heating element is coupled to the second portion of the substrate, and configured to produce a second thermal output. The second thermal output is different from the first thermal output.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: April 27, 2021
    Assignee: Visby Medical, Inc.
    Inventors: Boris Andreyev, Brian Ciopyk, Victor Briones, Jonathan Hong, David Swenson, Gregory Loney, Adam De La Zerda, Steven Chu
  • Publication number: 20210039097
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: October 14, 2020
    Publication date: February 11, 2021
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Patent number: 10905401
    Abstract: Ultrasound imaging systems and methods with frequency (spectral) compounding for speckle reduction are disclosed. In one aspect, an ultrasound imaging system includes a transducer probe with interleaved transmit and receive arrays. The system may utilize ultrasound pulses having an optimized time-bandwidth product. In one aspect, a transducer probe with separate transmit and receive elements can enable transmission and reception of multiple ultrasound pulses, each centered at a different frequency, during the time of one A-scan. Thus, such a system can capture multiple independent speckle images without reducing overall B-mode framerate. In another aspect, the system may transmit a broadband pulse and may obtain separate speckle images by filtering the received echo using multiple spectral filters. The system may compound multiple images captured at different frequencies to provide speckle reduction.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: February 2, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yilei Li, Steven Chu
  • Publication number: 20200406256
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Patent number: 10842358
    Abstract: Example embodiments relate to endoscopic systems. The system includes an outer assembly and main assembly. The outer assembly may include proximal and distal ends and outer anchor assembly. The outer anchor assembly may include a first expandable member and first outer pressure opening. The first expandable member may expand radially outwards. The main assembly may include proximal and distal ends and a navigation assembly. The navigation assembly may include an instrument, second expandable member, bendable section, extendible section, and first pressure opening. The extendible section may include proximal and distal ends. The proximal end of the extendible section may be secured in position relative to the distal end of the outer assembly. The extendible section may be configurable to extend and contract. The first main pressure opening may be configurable to apply a negative pressure.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: November 24, 2020
    Assignee: Bio-Medical Engineering (HK) Limited
    Inventors: Chung-Kwong Yeung, Steven Chu, Wing Fai Lam